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2018 Korean Heart Rhythm Society Guidelines for Antiarrhythmic Drug Therapy in Non-valvular Atrial Fibrillation

2018 대한부정맥학회 비판막성 심방세동 환자의 동율동 조절 약제 지침

  • Kang, Ki-Woon (Department of Cardiology, Eulji University Hospital School of Medicine) ;
  • Shim, Jaemin (Department of Cardiology, Korea University Anam Hospital, Korea University College of Medicine) ;
  • Ahn, Jinhee (Department of Cardiology, Busan National University College of Medicine) ;
  • Lee, Dae In (Department of Cardiology, Chungbuk National University College of Medicine) ;
  • Kim, Jun (Department of Cardiology, Asan Medical Center, Ulsan University College of Medicine) ;
  • Joung, Boyoung (Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Choi, Kee-Joon (Department of Cardiology, Asan Medical Center, Ulsan University College of Medicine)
  • 강기운 (을지대학교 의과대학 을지대학교병원 심장내과) ;
  • 심재민 (고려대학교 의과대학 고려대학교 안암병원 순환기내과) ;
  • 안진희 (부산대학교 의과대학 부산대학교병원 순환기내과) ;
  • 이대인 (충북대학교 의과대학 충북대학교 병원 심장내과) ;
  • 김준 (울산대학교 의과대학 서울아산병원 심장내과) ;
  • 정보영 (연세대학교 의과대학 세브란스병원 심장내과) ;
  • 최기준 (울산대학교 의과대학 서울아산병원 심장내과)
  • Published : 2018.04.01

Abstract

Rhythm control therapy is the main strategy for restoring and maintaining sinus rhythm in patients with non-valvular atrial fibrillation (NVAF). Sinus rhythm is better restored and maintained with antiarrhythmic drugs than with placebo treatment. In addition, catheter ablation or combination therapy is more effective than antiarrhythmic drugs for treating NVAF. However, in most clinical trials to date, rhythm control therapy has resulted in neutral clinical outcomes compared with rate control therapy. The decision to undergo rhythm control therapy should be based on age, atrial fibrillation (AF)-related symptoms, type of AF, structural heart disease, and underlying comorbidities. For now, rhythm control therapy is indicated to improve symptoms in patients with NVAF who have refractory symptoms after adequate rate control therapy. The Korean Heart Rhythm Society organized the Korean AF Management Guideline Committee and analyzed all available data, including South Korean patients with NVAF. This review article provides general principles and detailed methodology for rhythm control therapy in South Korean patients with NVAF.

Keywords

References

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