The Korean Journal of Medicine

  • 제93권1호
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  • Pages.50-54
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  • 2018
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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진행 담낭암에서 포트시스템을 이용한 간동맥항암제 주입 요법

Hepatic Arterial Infusion Chemotherapy Using the Port System in Advanced Gallbladder Cancer

  • 은종렬 (서남대학교 의과대학 명지병원 내과) ;
  • 김재운 (영남대학교 의과대학 영상의학과학교실) ;
  • 최준혁 (영남대학교 의과대학 병리학교실)
  • Eun, Jong Ryeol (Department of Internal Medicine, Myongji Hospital, Seonam University College of Medicine) ;
  • Kim, Jae Woon (Department of Radiology, Yeungnam University College of Medicine) ;
  • Choi, Joon Hyuk (Department of Pathology, Yeungnam University College of Medicine)
  • 투고 : 2011.02.08
  • 심사 : 2011.03.31
  • 발행 : 2018.02.01
⟨ 이전 논문 다음 논문 ⟩

초록

Gallbladder (GB) cancer is relatively rare and has a poor prognosis, with a median survival time of less than 3 months. It is resistant to chemotherapy. Therefore, the role of systemic chemotherapy is limited. However, administering the anticancer agent directly into the hepatic artery can result in a higher drug concentration in the cancer tissue. In this paper, we report a case of advanced GB cancer treated with hepatic arterial infusion chemotherapy (HAIC) using the port system. The patient received six cycles of HAIC with 5-fluorouracil ($750mg/m^2$) and cisplatin ($25mg/m^2$); each cycle lasted for 4 days every month. The tumor showed objective response during HAIC, and the patient survived for 15 months from the first therapy. HAIC using the port system might be a promising therapeutic modality for treating locally advanced GB cancer.

키워드

참고문헌

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