The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Fundamental role of dendritic cells in inducing Th2 responses

  • Kim, Byoungjae (Department of Otorhinolaryngology-Head & Neck Surgery, Korea University College of Medicine) ;
  • Kim, Tae Hoon (Department of Otorhinolaryngology-Head & Neck Surgery, Korea University College of Medicine)
  • Received : 2016.06.30
  • Accepted : 2017.09.05
  • Published : 2018.05.01
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Abstract

A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.

Keywords

Acknowledgement

Supported by : National Research Foundation of Korea, Korea Health Industry Development Institute (KHIDI), Korea University Medical Center and Korea University Anam Hospital

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