참고문헌
- James OH, Edward LM, Holly TW. Dietary fat intake and regulation of energy balance: implications for obesity. J Nutr. 2000 ; 130 : 284S-8S. https://doi.org/10.1093/jn/130.2.284S
- Korea centers for disease control and prevention. Korea health statistics 2014: Korea national health and nutrition examination survey (KNHANES VI). 2016.
- Shin HY, Kang HT. Recent trends in the prevalence of underweight, overweight, and obesity in Korean adults: The korean national health and nutrition examination survey from 1998 to 2014. J Epidemiol. 2017 ; 27(9) : 413-9. https://doi.org/10.1016/j.je.2016.08.014
- Scott MG. Obesity, metabolic syndrome, and cardiovascular disease. J Clin Endocrinol Metab. 2004 ; 89(6) : 2595-600. https://doi.org/10.1210/jc.2004-0372
- Tseng YH, Cypess AM, Kahn CR. Cellular bioenergetics as a target for obesity therapy. Nat Rev Drug Discov. 2010 ; 9(6) : 465-82. https://doi.org/10.1038/nrd3138
- Song MY, Lim SK, Wang JH, Kim HJ. The root of Atractylodes macrocephala Koidzumi prevents obesity and glucose intolerance and increases energy metabolism in mice. Int J Mol Sci. 2018 ; DIO: 10.3390/ijms19010278.
- Daneschvar HL, Aronson MD, Smetana GW. FDAapproved anti-obesity drugs in the United states. Am J Med. 2016 ; 129(8) : 879.e1-6. https://doi.org/10.1016/j.amjmed.2016.02.009
- Kang JG, Park CY. Anti-obesity drugs: a review about their effects and safety. Diabetes Metab J. 2012 ; 36 : 13-25. https://doi.org/10.4093/dmj.2012.36.1.13
- Yun JW. Possible anti-obesity therapeutics from nature - A review. Phytochemistry. 2010 ; 71 : 1625-41. https://doi.org/10.1016/j.phytochem.2010.07.011
- Saad B, Zaid H, Shanak S, Kadan S. Herbal-derived anti-obesity compounds and their action mechanisms. Anti-diabetes and Anti-obesity Medicinal Plants and Phytochemicals. 2017 ; 129-44.
- Ye CL, Jiang CJ. Optimization of crude polysaccharides from Plantago asiatica L. by response surface methodology. Carbohydr Polym. 2011 ; 84 : 495-502. https://doi.org/10.1016/j.carbpol.2010.12.014
- Ravn H, Brimer L. Struture and antibacterial activity of plantamajoside, a caffeic acid sugar ester from Plantago major subs major . Phytochemistry. 1988 ; 27(11) : 3433-7. https://doi.org/10.1016/0031-9422(88)80744-1
- Tundis R, Bonesi M, Menichini F, Loizzo MR, Conforti F, Statti G, Pirisi FM, Menichini F. Antioxidant and anti-cholinesterase activity of Globularia meridionalis extracts andisolatedconstituents. NatProdCommun. 2012 ; 7 : 1015-20.
- Danae CO, Sugeyla BG, Jaime RBB, Rola AA, Veronica RL. Anti-inflammatory activity of iridoids and verbascoside isolated from Castilleja tenuiflora. 2013 ; 18(10) : 12109-18. https://doi.org/10.3390/molecules181012109
- Kim SY, Jeong MJ, Kim YJ, Lee UT, Choo ST. Effect of Plantaginis asiaticae Folium water extract on body fat loss in high fat-induced obese C57BL/6 mice. Kor J Herbol. 2018 ; 33(2) : 59-68. https://doi.org/10.6116/KJH.2018.33.2.59
- Turel I, Hanefi H, Erten R, Oner AC, Cengiz N, Yilmaz O. Hepatoprotective and antiinflammatory activities of Plantago major L. Indian J Pharmacol. 2009 ; 41(3) : 120-4. https://doi.org/10.4103/0253-7613.55211
- Park SJ, Sihn EH, Kim CA. Component analysis and antioxidant activity of Plantago asiatica L. Korea J food Preserv 2011 ; 18(2) : 212-8. https://doi.org/10.11002/kjfp.2011.18.2.212
- Hu JL, Nie SP, Wu QM, Li C, Fu ZH, Gong J, Cui SW, Xie MY. Polysaccharide from seeds of Plantago asiatica L. affects lipid metabolism and colon microbiota of mouse. J Agric Food Chem. 2014 ; 62(1) : 229-34. https://doi.org/10.1021/jf4040942
- Huang DF, Xie MY, Yin JY, Nie SP, Tang YF, Xie WM, Zhou C. Immunomodulatory activity of the seeds of Plantago asiatica L. J Ethnopharmacol. 2009 ; 124(3) : 493-8. https://doi.org/10.1016/j.jep.2009.05.017
- Yin JY, Nie SP, Zhou C, Wan Y, Xie MY. Chemical characteristics and antioxidant activities of polysaccharide purified from the seeds of Plantago asiatica L. J Sci Food Agric. 2009 ; DOI 10.1002/jsfa.3793.
- Hwang JT, Kwon DY, Yoon SH. AMP-activated protein kinase: a potential target for the disease prevention by natural occurring polyphenols. N Biotechnol. 2009 ; 26 : 17-22. https://doi.org/10.1016/j.nbt.2009.03.005
- O'Neill HM, Holloway GP, Steinberg GR. AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity. Mol Cell Endocrinol. 2013 ; 366 : 135-51. https://doi.org/10.1016/j.mce.2012.06.019
- Hawley SA, Davison M, Wood A, Davies SP, Besi RK, Carling D, Hardie DG. Characterization of the AMP-activated protein kinase from rat liver, and identification of threonine-172 as the major site at which it phos-phorylates and activates AMPactivated protein kinase. J Biol Chem. 1996 ; 271 : 27879-87. https://doi.org/10.1074/jbc.271.44.27879
- Kong CS, Kim JA, Kim SK. Anti-obesity effect of sulfated glucosamine by AMPK signal pathway in 3T3-L1 adipocytes. Food Chem Toxicol. 2009 ; 47 : 2401-6. https://doi.org/10.1016/j.fct.2009.06.010
- Spiegelman BM, Flier JS. Obesity and the Regulation of Energy Balance. Cell. 2002 ; 104 : 531-43.
- Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ. AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem. 2004 ; 279 : 12005-8. https://doi.org/10.1074/jbc.C300557200
- Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Muller C, Carling D, et al. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002 ; 415 : 339-43. https://doi.org/10.1038/415339a
- Hardie DG, Hawley SA, Scott JW. AMP-activated protein kinase-development of the energy sensor concept. J Physiol. 2006 ; 574 : 7-15. https://doi.org/10.1113/jphysiol.2006.108944
- Dietschy JM, Turley SD, Spady DK. Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res. 1993 ; 34 : 1637-59.
- McGarry JD, Brown NF. The mitochondrial carnitine palmitoyltransferase system-From concept to molecular analysis. Eur J Biochem. 1997 ; 244 : 1-14. https://doi.org/10.1111/j.1432-1033.1997.00001.x
- Clouet P, Henninger C, Bard J. Study of some factors controlling fatty acid oxidation in liver mitochondria of obese Zucker rats. Biochem J. 1986 ; 239 : 103-8. https://doi.org/10.1042/bj2390103
- Brown MS, Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 1997 ; 89 : 331-40. https://doi.org/10.1016/S0092-8674(00)80213-5
- Kolehmainen M, Vidal H, Alhava E, Uusitupa MIJ. Sterol regulatory element binding protein 1c (SREBP-1c) expression in human obesity. Obes Res. 2001 ; 9(11) : 706-12. https://doi.org/10.1038/oby.2001.95
- Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis on the liver. J Clin Invest. 2002 ; 109 : 1125-31. https://doi.org/10.1172/JCI0215593
- Ji C, Chan C, Kaplowitz N. Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model. J Hepatol. 2006 ; 45 : 717-24. https://doi.org/10.1016/j.jhep.2006.05.009
- Kalupahana NS, Claycombe KJ, Moustaid-Moussa N. (n-3) fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights. Adv Nutr. 2011 ; 2(4) : 304-16. https://doi.org/10.3945/an.111.000505
- Harms M, Seale P. Brown and beige fat: development, function and therapeutic potential. Nat Med. 2013 ; 19(10) : 1252-63. https://doi.org/10.1038/nm.3361
- Palou A, Pico C, Bonet ML, Oliver P. The uncoupling protein, thermogenin. Int J Biochem Cell Biol. 1998 ; 30 : 7-11. https://doi.org/10.1016/S1357-2725(97)00065-4
-
Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J. Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a
$PPAR{\gamma}$ agonist. Am J Physiol Endocrinol Metab. 2008 ; 295 : 287-96. https://doi.org/10.1152/ajpendo.00035.2008 - Francesc V, Roser I, Marta G. PPARs in the control of uncoupling proteins gene expression. PPAR Res. 2007 ; DIO:10.1155/2007/74364.
- Festuccia WT, Blanchard PG, Richard D, Deshaies Y. Basal adrenergic tone is required for maximal stimulation of rat brown adipose tissue UCP1 expression by chronic PPAR-gamma activation. Am J Physiol Regul Integr Comp Physiol. 2010 ; DIO:10.1152/ajpregu.00821.
- Peng Z, Borea PA, Varani K, Wilder T, Yee H, Chiriboga L. Adenosine signaling contributes to ethanol-induced fatty liver in mice. J Clin Invest. 2009 ; 119 : 582-94. https://doi.org/10.1172/JCI37409
-
Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunffld C, Feingold KR. Up-regulation of peroxisome proliferator-activated receptors (PPAR-
${\alpha}$ ) and PPAR-${\gamma}$ messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-${\gamma}$ -responsive adipose tissue-specific genes in the liver of obese diabetic mice. Endocrinology. 2000 ; 141(11) : 4021-31. https://doi.org/10.1210/endo.141.11.7771 -
Spiegelman BM. PPAR-
${\gamma}$ : adipogenic regulator and thiazolidinedione receptor. Diabetes. 1998 ; 47: 507-14. https://doi.org/10.2337/diabetes.47.4.507 -
Jones JR, Barrick C, Kim KA, Lindner B, Fujimoto Y. Deletion of
$PPAR{\gamma}$ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. Proc Natl Acad Sci USA. 2005 ; 102 (17) : 6207-12. https://doi.org/10.1073/pnas.0306743102