Advances in environmental research

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Determination of antibiotics by SPE-LC-MS/MS in wastewater and risk assessment

  • Aydin, Senar (Department of Environmental Engineering, Faculty of Engineering and Architecture, Necmettin Erbakan University) ;
  • Aydin, Mehmet E. (Department of Civil Engineering, Faculty of Engineering and Architecture, Necmettin Erbakan University) ;
  • Ulvi, Arzu (Department of Environmental Engineering, Faculty of Engineering and Architecture, Necmettin Erbakan University) ;
  • Kilic, Havva (Department of Environmental Engineering, Faculty of Engineering and Architecture, Necmettin Erbakan University)
  • Received : 2018.06.01
  • Accepted : 2019.02.20
  • Published : 2018.09.25
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Abstract

In this study, conditions of solid phase extraction (SPE) for determination of some antibiotics such as trimethoprim, oxytetracycline, erythromycin, clarithromycin, azythromycin, doxycycline, sulfamethazine, ciprofloxacin, chlortetracycline, sulfamethoxazole in wastewaters were optimized. After the optimum volume and pH of the sample were determined, the effect of the concentration of the compounds and matrix were investigated. The highest recovery rates for antibiotic compounds were determined between 82% and 105% in 200 mL sample volume and pH 2.5. Then, antibiotic compounds were investigated in influent and effluent samples taken from Konya Urban Wastewater Treatment Plant. The concentration of the antibiotics was detected range of 0.11-101 ng/L in influent waters and

Keywords

Acknowledgement

Supported by : Turkish Academia of Sciences

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