Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Vitamin D intake and Diabetes Mellitus in Korean Adults

한국 성인의 비타민 D와 당뇨병의 관련성

  • Hwang, Yerin (Department of Preventive Medicine, Gachon University College of Medicine) ;
  • Kwak, Jung Hyun (Department of Preventive Medicine, Gachon University College of Medicine) ;
  • Kim, Junghoon (Department of Preventive Medicine, Gachon University College of Medicine) ;
  • Choi, Yoon-Hyeong (Department of Preventive Medicine, Gachon University College of Medicine)
  • 황예린 (가천대학교 의과대학 예방의학과) ;
  • 곽정현 (가천대학교 의과대학 예방의학과) ;
  • 김정훈 (가천대학교 의과대학 예방의학과) ;
  • 최윤형 (가천대학교 의과대학 예방의학과)
  • Received : 2018.04.01
  • Accepted : 2018.04.20
  • Published : 2018.04.28
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Abstract

Objectives: This study aimed to investigate the association between vitamin D deficiency and the risk of diabetes mellitus, and also examined whether their association is differed by sex and age. Methods: We analyzed the data from 28,135 subjects ${\geq}20years$ old who were registered for the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2014. Vitamin D was measured using serum 25-hydroxyvitamin D (25(OH)D) concentrations. Results: After adjusting for potential confounders (age, sex, education, income, total energy intake, smoking, physical activity, body mass index, and waist circumference), lower vitamin D was dose-dependently associated with a higher risk of diabetes mellitus (p-trend=0.004). When compared with the sufficient group (25(OH)D ${\geq}30ng/mL$), the severe deficient group (25(OH)D <10 ng/mL) had 1.46 (95% CI 1.11-1.94) odds ratio for the risk of diabetes mellitus. This association was markedly strong in men and adults aged ${\geq}40$, whereas no significant association was observed in women and adults aged <40. Conclusions: We found that vitamin D deficiency may be associated with an increased risk for diabetes mellitus in Korean adults. Our findings suggest that intake of higher vitamin D may help reduce the risk of diabetes mellitus.

Keywords

References

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