Journal of Plant Biotechnology

The Korean Society of Plant Biotechnology (한국식물생명공학회)
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Current status and prospects of the meiosis-specific function of recombinase in plants

식물의 감수분열에서 상동 재조합 효소 특이 기능의 연구현황 및 전망

  • Jung, Yu Jin (Department of Horticultural Life Science, Hankyong National University) ;
  • Nam, Ki Hong (Department of Horticultural Life Science, Hankyong National University) ;
  • Kim, Tae Sung (Department of Agricultural Sciences, Korea National Open University) ;
  • Lee, In Hae (Biological Resources Division, National Institute of Biological Resources) ;
  • Cho, Yong-Gu (Department of Crop Science, Chungbuk National University) ;
  • Kang, Kwon Kyoo (Department of Horticultural Life Science, Hankyong National University)
  • 정유진 (국립한경대학교 원예생명과학과) ;
  • 남기홍 (국립한경대학교 원예생명과학과) ;
  • 김태성 (한국방송통신대학교 농학과) ;
  • 이인혜 (국립생물자원관 생물소재연구단 연구팀) ;
  • 조용구 (충북대학교 식물자원학과) ;
  • 강권규 (국립한경대학교 원예생명과학과)
  • Received : 2018.03.26
  • Accepted : 2018.03.26
  • Published : 2018.03.31
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Abstract

Meiosis is a specialized cell division, essential in most reproducing organisms to halve the number of chromosomes, thereby enabling the restoration of ploidy levels during fertilization. A key step in meiosis is homologous recombination, which promotes homologous pairing and generates crossovers (COs) to connect homologous chromosomes until their separation at anaphase I. These CO sites, seen cytologically as chiasmata, represent a reciprocal exchange of genetic information between two homologous non-sister chromatids. RAD51, the eukaryotic homolog of the bacterial RecA recombinase, plays a central role in homologous recombination (HR) in yeast and animals. Loss of RAD51 function causes lethality in the flowering plant, Arabidopsis thaliana, suggesting that RAD51 has a meiotic stage-specific function that is different from homologous pairing activity.

Keywords

References

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