Tuberculosis and Respiratory Diseases

  • 제81권1호
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  • Pages.42-48
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  • 2018
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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Development of Prediction Equation of Diffusing Capacity of Lung for Koreans

  • Hwang, Yong Il (Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital) ;
  • Park, Yong Bum (Lung Research Institute of Hallym University College of Medicine) ;
  • Yoon, Hyoung Kyu (Division of Pulmonology, Critical Care and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Lim, Seong Yong (Division of Pulmonary and Critical Care Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Tae-Hyung (Division of Pulmonology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Park, Joo Hun (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ajou University School of Medicine) ;
  • Lee, Won-Yeon (Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Park, Seong Ju (Division of Pulmonary, Allergy and Critical Care Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School) ;
  • Lee, Sei Won (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Woo Jin (Department of Internal Medicine, Kangwon National University School of Medicine) ;
  • Kim, Ki Uk (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Shin, Kyeong Cheol (Regional Center for Respiratory Disease, Yeungnam University Medical Center, Yeungnam University College of Medicine) ;
  • Kim, Do Jin (Division of Allergy and Respiratory Medicine, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital) ;
  • Kim, Hui Jung (Division of Pulmonary and Critical Care Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine) ;
  • Kim, Tae-Eun (Department of Clinical Pharmacology, Konkuk University School of Medicine) ;
  • Yoo, Kwang Ha (Department of Internal Medicine, Konkuk University Medical Center) ;
  • Shim, Jae Jeong (Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital)
  • 투고 : 2017.11.03
  • 심사 : 2017.12.07
  • 발행 : 2018.01.31
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초록

Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=-10.4433-0.1434${\times}$age (year)+0.2482${\times}$heights (cm); DLco/alveolar volume (VA)=6.01507-0.02374${\times}$age (year)-0.00233${\times}$heights (cm). For women the prediction equations were described as followed: DLco=-12.8895-0.0532${\times}$age (year)+0.2145${\times}$heights (cm) and DLco/VA=7.69516-0.02219${\times}$age (year)-0.01377${\times}$heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

키워드

참고문헌

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피인용 문헌

  1. Validation of Previous Spirometric Reference Equations and New Equations vol.34, pp.47, 2019, https://doi.org/10.3346/jkms.2019.34.e304