The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Antioxidant and Anticancer Effects of Water Extract from Pleurotus eryngii, Flammulina velutipes

새송이버섯, 팽이버섯 열수추출물의 항산화 및 항암 활성

  • 류혜숙 (상지대학교 보건과학대학 식품영양학과) ;
  • 김수현 (구운식품연구소) ;
  • 전문희 (구운식품연구소) ;
  • 최해연 (공주대학교 외식상품학과)
  • Received : 2018.10.11
  • Accepted : 2018.12.10
  • Published : 2018.12.31
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Abstract

Various studies on the effect of mushroom, a member of phytonutrients, on inflammatory diseases have been reporter over the years, Among various species mushrooms, King oyster mushroom (Pleurotus eryngii) and winter mushroom (Flammulina velutipes) are popular dietary ingredients for Asian cuisine. The extracts from all the three mushrooms were used to determine the antioxidative effect and the cytotoxicity. Result analysis were repeated more than three times to get an average${\pm}$standard deviation, and statistical significance were confirmed by SPSS. As a result, total phenol content of the king oyster mushroom and the winter mushroom were $19.66{\pm}0.10mg/g$ and $22.08{\pm}1.10mg/g$, respectively. Also, the total flavonoid content was $15.21{\pm}1.31mg/g$ for the king oyster mushroom and $20.50{\pm}4.52mg/g$ for winter mushroom. The results in winter mushroom showed higher values in total phenol and flavonoid content than in the king oyster mushroom. All samples of extracts showed free radical DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activity with their 10 mg/mL concentration. These results indicate that the extract of the king oyster mushroom (Pleurotus eryngii) and the winter mushroom (Flammulina velutipes) may be possible phytonutrients with the anti-inflammatory and the anti-cancer effect.

Keywords

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Fig. 1. Cytotoxicity of water extract from Pleurotus eryngii on HEK-293 (transformed primary human embryonal kidney) cells.

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Fig. 2. Cytotoxicity of water extract from Pleurotus eryngii on AGS (human gastric carcinoma), MCF-7 (human breast adenocarcinoma) and HepG2 (human hepatoblastoma) cells.

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Fig. 4. Cytotoxicity of water extract from Flammulina velutipes on AGS (human gastric carcinoma), MCF-7 (human breast adenocarcinoma) and HepG2 (human hepatoblastoma) cells.

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Fig. 3. Cytotoxicity of water extract from Flammulina velutipes on HEK-293 (transformed primary human embryonal kidney) cells.

Table 1. Total phenols and flavonoid contents of water extract from Pleurotus eryngii and Flammulina velutipes

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Table 2. DPPH radical scavenging activities of water extract from Pleurotus eryngii and Flammulina velutipes

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Table 3. ABTS radical scavenging activities of water extract from Pleurotus eryngii and Flammulina velutipes

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Table 4. Reducing power of water extracts from Pleurotus eryngii and Flammulina velutipes

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Table 5. Ferric-reducing antioxidant power of water extracts from Pleurotus eryngii and Flammulina velutipes

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