Korean Journal of Microbiology (미생물학회지)

The Microbiological Society of Korea (한국미생물학회)
권호 표지
DOI QR코드

DOI QR Code

Complete genome of methicillin resistant Staphylococcus epidermidis Z0117SE0042 isolated from human nasal mucosa

사람 코점막에서 분리된 메티실린 내성 Staphylococcus epidermidis Z0117SE0042의 유전체 염기서열

  • Patil, Kishor Sureshbhai (Division of Biotechnology, Chonbuk National University) ;
  • Oh, Jae-Young (Department of Veterinary Internal Medicine, Konkuk University) ;
  • Han, Jae-Ik (Laboratory of Wildlife Diseases, College of Veterinary Medicine, Chonbuk National University) ;
  • Song, Wonkeun (Department of Laboratory Medicine, College of Medicine, Hallym University) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, Konkuk University) ;
  • Chae, Jong-Chan (Division of Biotechnology, Chonbuk National University)
  • Received : 2018.12.07
  • Accepted : 2018.12.09
  • Published : 2018.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Methicillin resistant Staphylococcus epidermidis Z0117SE0042 was isolated from nasal mucosa of veterinarian. The complete genome of strain Z0117SE0042 contains a 2.5 Mb chromosome and two circular plasmids of about 24 kb and 23 kb. Analysis of the genome determined in this study may contribute to evaluate the presence and prevalence of antibiotic resistant genes in normal flora of human.

메티실린 내성 Staphylococcus epidermidis Z0117SE0042을 수의사의 코점막으로부터 분리하였다. 완전 해독된 Z0117SE0042 균주의 게놈은 약 2.5 Mb의 염색체와 24 kb, 23 kb 크기의 2개 플라스미드로 구성되어 있었다. 본 연구에서 해독된 유전체 정보는 인간의 정상미생물상에 존재하는 항생제 내성유전자의 분포를 추적하는데 유용한 기반이 될 것으로 기대된다.

Keywords

MSMHBQ_2018_v54n4_468_f0001.png 이미지

Fig. 1. SCCmec gene organization in Z0117SE0042 strain.

Table 1. Genome features of Staphylococcus epidermidis Z0117SE0042

MSMHBQ_2018_v54n4_468_t0001.png 이미지

References

  1. Baig S, Johannesen TB, Overballe-Petersen S, Larsen J, Larsen AR, and Stegger M. 2018. Novel SCCmec type XIII (9A) identified in an ST152 methicillin-resistant Staphylococcus aureus. Infect. Genet. Evol. 61, 74-76. https://doi.org/10.1016/j.meegid.2018.03.013
  2. Chin CS, Alexander DH, Marks P, Klammer AA, Drake J, Heiner C, Clum A, Copeland A, Huddleston J, Eichler EE, et al. 2013. Nonhybrid, finished microbial genome assemblies from longread SMRT sequencing data. Nat. Methods 10, 563-569. https://doi.org/10.1038/nmeth.2474
  3. Conlan S, Mijares LA, Becker J, Blakesley RW, Bouffard GG, Brooks S, Coleman H, Gupta J, Gurson N, Park M, et al. 2012. Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates. Genome Biol. 13, R64. https://doi.org/10.1186/gb-2012-13-7-r64
  4. Diep BA, Gill SR, Chang RF, Phan TH, Chen JH, Davidson MG, Lin F, Lin J, Carleton HA, Mongodin EF, et al. 2006. Complete genome sequence of USA300, an epidemic clone of communityacquired meticillin-resistant Staphylococcus aureus. Lancet 367, 731-739. https://doi.org/10.1016/S0140-6736(06)68231-7
  5. Galac MR, Stam J, Maybank R, Hinkle M, Mack D, Rohde H, Roth AL, and Fey PD. 2017. Complete genome sequence of Staphylococcus epidermidis 1457. Genome Announc. 5, e00450-17.