참고문헌
- Wolchok J.D, Saenger Y, The Mechanism of Anti-CTLA-4 Activity and the Negative Regulation of T-Cell Activation, The Oncologist 2008;13:Supplement 4-29. https://doi.org/10.1634/theoncologist.13-S4-2
- Buchbinder E. I, Desai A, CTLA-4 and PD-1 Pathways Similarities, Differences, and Implications of their Inhibition. Am J ClinOncol 2016;39:98-106.
- Bardhan K, Anagnostou T, Boussiotis V.A, The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation. Front Immunol 2016;7:550:1-17.
- Shi L, Chen S, Yang L, et al. The Role of PD-1and PD-L1 in T-cell Immune Suppression in Hematological Malignancies. J Hematol Oncol 2013;6:74-80.
- Hodi F.S, O'Day S.J, McDermott D.F, et al. Improved Survival with Ipilimumb in Patients with Metastatic Melanoma. N Engl J Med 2010;363:711-23. https://doi.org/10.1056/NEJMoa1003466
- Graziani G, Tentori L, Navarra P, Ipilimumab: A Novel Immunostimulatory Monoclonal Antibody for the Treatment of Cancer. Pharmacol Res 2012;65:9-22. https://doi.org/10.1016/j.phrs.2011.09.002
- Larkin J, Chiarion-Sileni V, Gonzalez R, et al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. N Engl J Med 2015;373:23-34. https://doi.org/10.1056/NEJMoa1504030
- Hellmann M.D, Rizvi N.A, Goldman J.W, et al. Nivolumab plus ipilimumab as First-line Treatment for Advanced Non-Small-Cell Lung Cancer(CheckMate 012):Results of an Open-Label, Phase 1, Multicohort Study. Lancet Oncol 2017;18: 31-41.
- Robert C, Long G.V, Brady B, et al. Nivolumab in Previously Untreated Melanoma without BRAF Mutation. N Engl J Med 2015;372:320-30. https://doi.org/10.1056/NEJMoa1412082
- Ribas A, Puzanov I, Dummer R, et al. Pemtrolizumab versus Investigator-Choice Chemotherapy for Ipilimumab-Refractory Melanoma (KEYNOTE-002): a randomized, controlled, phase 2 trial. Available from www.thelancet.com/oncology. 2015;16:908-18. https://doi.org/10.1016/S1470-2045(15)00083-2
- Robert C, Schachter J, Long G.V, et al. Pembrolizumab versus Ipilimumab in Advanced Melanoma. N Engl J Med 2015;372:2521-32.
- Rosenberg J.E, Hoffman-Censits J, Powles T, et al. Atezolizumab in Patients with Locally Advanced and Metastatic Urothelial Carcinoma who have Progressed Following Treatment with Platinum-Based Chemotherapy: A Single Arm, phase 2 trial. Lancet 2016;387:1909-20.
- Kaufman H, Russell J, Hamid O, et al. Avelumab in Patients with Chemotherapy-Refractory Metastatic Merkel Cell Carcinoma: A Multicenter, Single-Group, Open-Label, Phase 2 Trial. Lancet Oncol 2016; 17:1374-85.
- Massard C, Gordon M. S, Sharma S, et al. Safety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients with Advanced Urothelial Bladder Cancer. J ClinOncol 2016;34:3119-26. https://doi.org/10.1200/JCO.2016.67.9761
- Bellmunt J, Powles T, Vogelzang N.J, A Review on the Evolution of PD-1/PD-L1 immunotherapy for Bladder Cancer: The Future is Now. Cancer Treat Rev 2017;54:58-67. https://doi.org/10.1016/j.ctrv.2017.01.007
- Topalian S.L, Taube J.M, Anders R.A., et al. Mechanism-Driven Biomarkers to Guide Immune Checkpoint Blockade in Cancer Therapy. Nat Rev Cancer 2016;16:275-87. https://doi.org/10.1038/nrc.2016.36
- Topalian S.L, Hodi S. Brahmer J.R, et al. Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer. N Engl J Med 2012; 366:2443-54. https://doi.org/10.1056/NEJMoa1200690
- Teixido C, Gonzalez-Cao M, Karachaliou N, et al. Predictive Factors for Immunotherapy in Melanoma. Ann Transl Med 2015;3:208.
- Taube J.M, Klein A, Brahmer J. R, et al. Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy. Clin Cancer Res 2014; 20: 5064-74. https://doi.org/10.1158/1078-0432.CCR-13-3271
- Messina J, Fenstermacher D.A, Eschrich S, et al. 12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy. Sci Rep 2012;2:765-71. https://doi.org/10.1038/srep00765
- Zaretsky J.M, Diaz A.G, Shin D.S, et al. Mutations Associated with Acquired Resistance to PD-1 Blocked in Melanoma. N Engl J Med 2016;375:819-29. https://doi.org/10.1056/NEJMoa1604958
- Snyder A, Makarov V, Merghoub T, et al. Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma. N Engl J Med 2014;371:2189-99.
- Heppt M.V, Dietrich C, Graf S.A, Ruzicka T, Tietze J.K, Berking C, The Systemic Management of Advanced Melanoma in 2016. Oncol Res Treat 2016;39:635-42.
- Gibney G.T, Weiner L.M, Atkins M.B, Predictive Biomarkers for Checkpoint Inhibitor-Based Immunotherapy. Lancet Oncol 2016;16: e542-51.
- Pennock G.K, Chow L. Q.M, The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment. The Oncologist 2015;20:812-22. https://doi.org/10.1634/theoncologist.2014-0422
- Ansell S.M, Lesokhin A.M, Borrello I, et al. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma. N Engl J Med 2015;372:311-9. https://doi.org/10.1056/NEJMoa1411087
- Weber J.S, D'Angelo S.P, Minor D, et al. Nivolumab Versus Chemotherapy in Patients with Advanced Melanoma who Progressed after Anti-CTLA-4 Treatment (CheckMate 037): A Randomized, Controlled, Open-Label, Phase 3 Trial. Lancet Oncol 2015;16:375-84. https://doi.org/10.1016/S1470-2045(15)70076-8
- Sadraei N. H, Sikora A. G, Brizel D. M, Immunotherapy and Checkpoint Inhibitors in Recurrent and Metastatic Head and Neck Cancer. asco.org/edbook 2016;e277-81.
- Rozali E.N, Hato S.V, Robinson B.W, Lake R.A, Lesterhuis W.J, Programmed Death Ligand 2 in Cancer-Induced Immune Suppression, Clinical and Developmental Immunology. 2012; Article ID 656340:1-8.
- Rizvi N.A, Mazieres J, Planchard D, et al. Activity and Safety of Nivolumab, an Anti-PD-1 Immune Checkpoint inhibitor, for Patients with Advanced, Refractory Squamous Non-Small-Cell Lung Cancer (CheckMate 063): A Phase 2, Single-Arm Ttrial. Lancet Oncol 2015; 16:257-65.
- Apolo A.B, Infante J.R, Balmanoukian A, et al. Avelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study. J Clin Oncol 2016;35:2117-26.
- LiY, Li F, Jiang F, et al. A Mini-Review for Cancer Immunotherapy: Molecular Understanding of PD-1/PD-L1 Pathway &Translational Blockade of Immune Checkpoints. Int J Mol Sci 2016;17:1151-73. https://doi.org/10.3390/ijms17071151
- Yu H, Boyle T. A, Zhou C, Rimm D. L, Zhou C, Hirsh F.R, PD-L1 Expression in Lung Cancer. J Thorac Oncol 2016;11:964-75.
- Garon E.B, Rizvi N. A, Hui, et al. Pembrolizumab for the Treatmentof Non-Small-Cell Lung Cancer. N Engl J Med. 2015;372:2018-28. https://doi.org/10.1056/NEJMoa1501824
- Nghiem P.T, Bhatia S, Lipson E.J, et al. PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma. N Engl J Med 2016;374:2542-52. https://doi.org/10.1056/NEJMoa1603702
- Mozzillo N., Ascierto P.A., Melanoma: the Role of Surgery in the Era of New Therapies. J Transl Med 2014;12:195. https://doi.org/10.1186/1479-5876-12-195
- Patel M.R, Ellerton J, Agrawal M, et al. Avelumab (MSB0010718C; Anti-PD-L1) in Patients with Metastatic Urothelial Carcinoma Progressed after Platinum-Based Therapy or Platinum Ineligible. Ann Oncol 2016;27:Supplement 6: vi266-vi295.
피인용 문헌
- Tumour Regression via Integrative Regulation of Neurological, Inflammatory, and Hypoxic Tumour Microenvironment vol.28, pp.2, 2020, https://doi.org/10.4062/biomolther.2019.135
- Recent Advances in Monoclonal Antibody Therapy for Colorectal Cancers vol.9, pp.1, 2018, https://doi.org/10.3390/biomedicines9010039