동의신경정신과학회지 (Journal of Oriental Neuropsychiatry)

  • 제29권1호
  • /
  • Pages.9-20
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  • 2018
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  • 1226-6396(pISSN)
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  • 2234-4942(eISSN)
대한한방신경정신과학회 (The Korean Society of Oriental Neuropsychiatry)
권호 표지
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DOI QR Code

구미진심과립(九味鎭心顆粒)의 불안장애 활용에 대한 중의학 연구 고찰

A Study of Chinese Medicine on the Utilization of Jiuwei Zhenxin Granules for Anxiety Disorders

  • 김천중 (동신대학교 광주한방병원 한방신경정신과) ;
  • 정서윤 (동신대학교 광주한방병원 한방신경정신과) ;
  • 김경옥 (동신대학교 광주한방병원 한방신경정신과)
  • Kim, Cheon-Jung (Department of Neuropsychiatry, College of Oriental Medicine, Dongsin University) ;
  • Jeong, Seo-yun (Department of Neuropsychiatry, College of Oriental Medicine, Dongsin University) ;
  • Kim, Kyeong-Ok (Department of Neuropsychiatry, College of Oriental Medicine, Dongsin University)
  • 투고 : 2018.02.25
  • 심사 : 2018.03.17
  • 발행 : 2018.03.30
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초록

Objectives: The purpose of this study is to investigate the composition, origins, and utilization of Jiuwei Zhenxin Granules for anxiety disorders in Chinese medicine. Methods: Studies found in six databases were chosen, and major indicators were analyzed. Results: Jiuwei Zhenxin Granules are modified from Pyeonbojinsimdan on Taepyeonghyeminhwajegukbang. In Jiuwei Zhenxin Granule studies, there were significant effects in nine outcomes in twenty-four studies of primary anxiety disorders and seventeen outcomes were similar in effect to that in the control. Three outcomes in ten studies of secondary anxiety disorders showed significant effects, and five outcomes were similar in effect to that in the control. Conclusions: Jiuwei Zhenxin Granules is a prescription that focuses on harmony of vital energy (qi) and blood, and stability of mind. The significance of the constitution of Jiuwei Zhenxin Granules is similar to that of domestic anxiety disorder studies, so it seems to be applicable to anxiety disorders. With regard to domestic use of Jiuwei Zhenxin Granules, more research is needed on the dosage according to the formulation.

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참고문헌

  1. Min SG. Modern Psychiatry. 6th. Seoul:Ilchokak. 2015:344.
  2. Korea neuropsychiatry association. Textbook of Neuropsychiatry. 2nd. Seoul:Joongang. 2005:202-3.
  3. The textbook Compilation Committee of Neuropsychiatry of oriental medical schools in nation. The Neuropsychiatry of Oriental Medicine. 3rd edition. Seoul:Jipmoondang. 2016:220.
  4. Yang W. Hwangjaenaekyoung Yeongchu. Taipei. Taiwan Union Country Wind Press. 1976:104.
  5. Lee SG, Choi WJ. Antianxiety drug and Herb medicine. J. of Orental Neuropsychiatry. 2006;17(2):123-32.
  6. No DJ, Lee SR, Jung IC. The Recent Trends of Clinical Research on General Anxiety Disorder in Chinese Herbal Medicine. J. of Orental Neuropsychiatry. 2009;20(4):79-89.
  7. Lee EK, at al. A clinical report on anxiety improved by Insooksan. J. of Orental Neuropsychiatry. 2005;16(2):309-15.
  8. Yang SB, et al. Case Report of Generalized Anxiety Disorder Treated with Guibiondamtang-gami. Journal of korean oriental internal medicine. 2016;37(2):361-7.
  9. Zhang H, at al. Clinical Observation on Treatment of Generalized Anxiety Disorder with Jiuwei Zhenxin Granules and Paroxetine. China Journal of Modern Medicine. 2012;22(12):37-40.
  10. Kang KM, Bao M. Editing Formula Dictionary. Seoul:Euisungdang. 1991:284.
  11. Kuang WH, at al. Randomized Double-Blind Controlled Trial on Effectiveness and Safety of Jiu Wei Lv Ping Particle in the Treatment of Generallized Anxiety Disorder. Chinese J Evidence-Based Medicine. 2004;4(8):523-36.
  12. Wang YJ, Chen DF, Wang CY. Efficacy and safety of Zhexin Keli in treatment of generalized anxiety disorder; A multi-center randomized double-blind controlled trial. Chinese Mental Health Journal. 2013;27(2):126-31.
  13. Beijing Beilu Pharmaceutical Co., Ltd. -(http://www.beilu.com.cn/beilu-sc/show.php?id=101&channel=2)
  14. Wu Z, Lan K and Ying J. Jiuwei Zhenxin Granule in Treating 30 Cases of Generalized Anxiety Disorder. China Phamaceuticals. 2012;21(24):106-7.
  15. Li JH. Clinical Observation on Treatment of Generalized Anxiety Disorder with Jiuwei Zhenxin Granule Combined with Escitalopram. Chinesse journal of Integrative Medicine on Cardio/Cerebrovascular Disease. 2013;11(12):1466-7.
  16. Zhang DF, at al. Clinical Observation on 40 Cases of Generalized Anxiety Disorder Treated by Jiuwei Zhenxin Granule Combined with Buspirone. Guiding Journal of Traditional Chinese Medicine and Pharmacy. 2012;18(5):30-1.
  17. Yang XY. Clinical Study on Treatment of 62 Cases of Generalized Anxiety Disorder with Jiuwei Zhenxin Granule Combined with Buspirone. Guangming Journal of Chinese Medicine. 2015;30(1):54-7.
  18. Liu HZ. A comparative study of Jiuwei Zhenxin Granules and buspirone in the treatment of generalized anxiety disorder. Journal of Psychiatry. 2013;26(6):452-3.
  19. Qi GQ, at al. A comparative study of Jiuwei Zhenxin Granules and tandospirone in the treatment of elderly patients with generalized anxiety disorder. Journal of Clinical Psychiatry. 2014;24(2):123-4.
  20. Yang QZ, at al. Jiuwei Zhenxin Granules and Tandospirone Treatment of Generalized Anxiety Disorder. China Phamaceuticals. 2013;22(20):99-100.
  21. Ren Y, Hu DX. Clinical Observation on 30 Cases of Generalized Anxiety Disorder Syndrome Treated by Jiuwei Zhenxin Granule. Human Jpurnal of Traditional Medicine. 2015;31(8):59-60.
  22. Ren L, at al. Jiuwei Zhenxin Granule in Treating 33 Cases of Generalized Anxiety Disorder. Herald of Medicine. 2015;34(1):64-6.
  23. Wang YJ, Chen DF, Wang CY. A Multi-center, Randomized, Double-blind, Controlled Trial of Jiuwei Zhenxin Granule in Treating Generalized Anxiety Disorder. Chinese Mental Health Journal. 2013;27(2):126-31.
  24. Liang J. Clinical Observation on Treatment of Generalized Anxiety Disorder with Jiuwei Zhenxin Granule. China Phamacist. 2014;17(12):2078-9.
  25. Lu WQ. Observation of Curative Effect of Paroxetine Combined with Jiuwei Zhenxin Granule on Generalized Anxiety Disorder. China Journal Phamacoepidemiol. 2015;24(9):524-8.
  26. Pan YY, Wang YY, Liu Y. Effect of Jiuwei Zhenxin Granule on Oxidative Stress in Patients with General Anxiety. Modern Journal of Integrated Traditional Chinese and Western Medicine. 2016;25(36):4044-6.
  27. Li F. Influence of Jiuwei Zhenxin Granules Combined with Psychological Therapy on Patients with Generalized Anxiety Disorder. Gansu Science and Technology. 2016;32(4):126-8.
  28. Wei C. Clinical Analysis of 46 Cases of Generalized Anxiety Disorder Treated by Jiuwei Zhenxin Granule Combined with Escitalopram. Chinese Journal of Modern Drug Application. 2014;8(11):140-1.
  29. Guo L, at al. Treatment of 50 Cases of Generalized Anxiety with Jiuwei Zhenxin Granules Combined with Buspirone. Chinese Journal of Traditional Medical Science and Technology. 2012;19(6):568-9.
  30. Liang J. Observation on the Efficacy of Jiuwei Zhenxin Granule in Treating Generalized Anxiety. Chinese Journal of Pharmacoepidemiology. 2012;21(8):381-2.
  31. Wang XJ, Guo YM, Li XH. Clinical Observation on Treatment of Generalized Anxiety Disorder with Jiuwei Zhenxin Granule. JOURNAL OF NEW CHINESE MEDICINE. 2014;46(4):49-50.
  32. Hu J, at al. Clinical Study on Treatment of Generalized Anxiety Disorder with Jiuwei Zhenxin Granules. JApoplexy and Nervous Diseases. 2010;27(7):628-30.
  33. Fan XD, at al. Systematic evaluation of efficacy and safety of Jiuwei Zhenxin Granula in treating generalized anxiety disorder. Journal of Chengdu University of Traditional Chinese Medicine. 2017;40(2):123-7.
  34. Ji F. Clinical Study on Treatment of Generalized Anxiety with Tangospirone Combined with Jiuwei Zhenxin Granule. China Pharmacist. 2015;18(8):1355-7.
  35. Luo Z, at al. Comparative Study on Jiuwei Zhenxin Granules Combined with EEG biofeedback Therapy in the Treatment of Generalized Anxiety Disorder. China Pharmacist. 2013;16(8):1192-4.
  36. YAN Lijuan, LI Guangying. Clinical Observation on Jiuweizhenxin Granules With Counseling in Treatment of Generalized Anxiety Disorder. China Continuing Medical Education. 2015;7(15):181-2.
  37. Kong YJ, Li Y, Wei X. Clinical Observation on Chronic Atrophic Gastritis with Anxiety and Depression Treated by Jiuwei Zhenxin Granule. Chinese Journal of Integrated Traditional and Western Medicine on Digestion. 2014;22(11):644-7.
  38. Wang XJ. Clinical observation of right szopiclone combined with Jiuwei Zhenxin Granule in treating post-stroke anxiety and insomnia. Journal of China Prescription Drug. 2015;13(7):43-4.
  39. Wang H, at al. Clinical Observation on Treatment of Anxiety Associated with Schizophrenia with Jiuwei Zhenxin Granules and Paroxetine. Neural Injury And Functional Reconstruction. 2014;9(3):236-8.
  40. Guo JF. Clinical Analysis of Leptin Combined with Jiuwei Zhenxin Granule in Patients with Anxiety and Depression after Coronary Intervention. China Practical Medicine. 2016;11(26):39-40. https://doi.org/10.1186/s13020-016-0109-6
  41. Li XC, at al. Clinical Observation on 60 Cases of Post-stroke Anxiety Disorder Patients Treated by Jiuwei Zhenxin Granule. Journal of Traditional Chinese Medicine. 2015;56(4):323-6.
  42. Wang HL, Wang CS. Venlafaxine Combined with Jiuwei Zhenxin Granule in the Treatment of Perimenopausal Anxiety and Depression. China Medical Herald. 2015;12(2):86-8.
  43. Qiu B, at al. Clinical Observation of Jiuwei Zhenxin Granule in Treating Vascular Cognitive Impairment with Anxiety Symptoms. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease. 2015;13(6):733-5.
  44. Jing C, at al. Tamoxifen Capsule Combined with Jiuwei Zhenxin Granule in Treating Post-stroke Anxiety in 60 Cases. Herald of Medicine. 2014;33(8):1042-4.
  45. Wang GJ. Clinical Study on Treatment of Anxiety and Depression in Patients with Type 2 Diabetes with Jiuwei Zhenxin Granules. Information on Traditional Chinese Medicine. 2013;30(2):28-31.
  46. Xiao ZC, at al. Clinical Observation of Anxiety after Apoplexy Treated by Jiuwei Zhenxin Granule. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease. 2013;11(9):1078-9.
  47. Jang GA. Yugyeong. Seoul:Daesungmunhwasa. 1982:375-7.
  48. Li W. Editing Euhakipmun Vol.2. Seoul:Daesungmunhwasa. 1990:372-3.
  49. Yu T. Euhakjeongjong. Seoul:Sungbosa. 1986:274.
  50. Zhou MS. Euimunbogam. Seoul:Iljungsa. 1991:169-71.
  51. Li ZY. Euijongsimdok. Seoul:Seowondang. 1976:370-4.
  52. Cheng GP. Bijeung Euihaksimo. Seoul:Iljungsa. 1992:208-9.
  53. Gong TX. Manbunghuichun. Beijing:People's Medical Publishing House. 1984:226-9.
  54. Ju JH. Dangyesimbeobbuyeo. Seoul:Daesungmunhwasa. 1999:355-8.
  55. Zhang KB. Gyeongakjeonseo. Seoul:Jeongdam. 1999:345-8.
  56. Heo J. Donguibogam. Seoul:Namsandang. 1994:96-7.
  57. The textbook Compilation Committee of Herbal medicine of oriental medical schools in nation. Herbal medicine. Revision 2nd. Seoul:Jeongumsa. 2011:346,355,528,646.