한국해양바이오학회지 (Journal of Marine Bioscience and Biotechnology)

한국해양바이오학회 (The Korean Society for Marine Biotechnology)
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실리카테인: 생규화 및 응용

Silicatein: Biosilicification and Its Applications

  • 양병선 (포항공과대학교, 화학공학과) ;
  • 윤진영 (포항공과대학교, 화학공학과) ;
  • 차형준 (포항공과대학교, 화학공학과)
  • Yang, Byeongseon (Department of Chemical Engineering, Pohang University of Science and Technology) ;
  • Yun, Jin Young (Department of Chemical Engineering, Pohang University of Science and Technology) ;
  • Cha, Hyung Joon (Department of Chemical Engineering, Pohang University of Science and Technology)
  • 투고 : 2018.12.05
  • 심사 : 2018.12.20
  • 발행 : 2018.12.31
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초록

Silicon has become of increasing importance as the basic element of many high-technology products. Its synthesis is very difficult requiring high temperature solid-state reactions (> $1000^{\circ}C$) or lower temperature methods ($100-200^{\circ}C$) involving hydrothermal and solvothermal reactions under extreme pH conditions. In nature, on the other hand, a wide range of living organisms have collectively evolved the means of biosilicification at the astounding rate of gigatons/year. This is impressive because biosilicification in these organisms occurs under mild physiological conditions. Marine sponges possess the ability to sequester soluble silicon sources from their environments and assemble them into intricate 3D architecture. The advent of molecular biology has recently made it possible to glean molecular information about biosilicification from these systems and it turned out that enzyme silicatein is the core of biosilicification. In this review, biosilicification regulated by silicatein and its mechanism are described. Also, production of silicatein through recombinant technology and several applications of recombinant silicatein are described including immobilization of silicatein, formation of Au or Ag nanoparticles on nanowires, nanolithography approaches, core-shell materials, encapsulation, bone replacement materials, and microstructured optical fibers.

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