Fig. 1. Chromatograms of benzoic acid with 5 mM ammonium acetate (a) and 20 mM ammonium acetate (b) solution as an aqueous mobile phase. The mass fraction of benzoic acid was 40 mg/kg.
Fig. 2. Comparison of chromatograms for benzoic acid (3.4 min), methyl paraben (4.8 min) and butyl paraben (10.3 min) with 5 mM ammonium acetate solution (a) at pH 4.5 and (b) at pH 4.0. The mass fractions of benzoic acid, methyl paraben and butyl paraben were 40 mg/kg, 10 mg/kg and 10 mg/kg, respectively.
Fig. 3. Total ion chromatograms and benzoic acid chromatograms of soy sauce after (a) dilution, (b) Carb SPE cartridge and (c) C18 SPE cartridge. The soy sauce sample for (a) solution was from HSA. The soy sauce sample for (b) and (c) soy sauce was spiked with standard mixture solution into the soy sauce from the local market. The mass fraction of benzoic acid was 20 mg/kg, and the mass fractions of methyl paraben and butyl paraben were 4 mg/kg.
Table 1. Structures, pKa, solubilities and regulation limits for benzoic acid, methyl paraben, and butyl paraben
Table 2. Channels and collision energies for selected reaction monitoring of ID-LC/MS/MS
Table 3. ID-LC/MS/MS measurement results of 5 sub-samplings from soy sauce reference material
Table 4. Comparison of measured values by KRISS with reference values of benzoic acid, methyl paraben, and butyl paraben in soy sauce sample
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