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Influences of Antarctic Ocean Krill (Euphausia superba) on Lipid Components and A/G Ratio in Rats

남빙양 krill이 흰쥐의 혈청 지질성분 및 알부민/글로불린 비에 미치는 영향

  • Oh, Da-Young (Department of Food Science and Technology, Pusan National University) ;
  • Jin, Dong-Hyeok (Department of Food Science and Technology, Pusan National University) ;
  • Kang, Dong-Soo (Department of Marine Bio Food Science, Chonnam National University) ;
  • Lee, Young-Geun (Department of Food Science and Technology, Pusan National University) ;
  • Kim, Han-Soo (Department of Food Science and Technology, Pusan National University)
  • 오다영 (부산대학교 식품공학과) ;
  • 진동혁 (부산대학교 식품공학과) ;
  • 강동수 (전남대학교 해양바이오식품학과) ;
  • 이영근 (부산대학교 식품공학과) ;
  • 김한수 (부산대학교 식품공학과)
  • Received : 2018.07.03
  • Accepted : 2018.09.06
  • Published : 2018.11.30

Abstract

The aim of the study were to investigate the influences of krill (Euphausia superba) meal on the body weight, lipid metabolism functional improvement, blood glucose level, protein component in the sera of rats which fed experimental diets for 5 weeks. Serum concentrations of total cholesterol, Low-Density Lipoprotein (LDL)-cholesterol, free cholesterol, triglyceride (TG), phospholipid (PL) and blood glucose were higher in the control diet group (G1 group) than the control diet plus 10% krill meal group (G2 group), the control diet plus 20% krill meal group (G3 group), the control diet plus 30% krill meal group (G4 group), and a general dose and time independent one-way analysis of variance was performed to assess efficacy. Conversely depending on the content of krill meal for the High-Density Lipoprotein (HDL)-cholesterol level, it showed higher results. The concentrations of total protein, albumin and globulin in sera, there were not significant difference among the groups (p<0.05). The results indicate that a krill meal diet effectively inhibited increases in lipid elevation, blood glucose level in the sera of rats.

Keywords

References

  1. Assmann, G., Schulte, H., Cullen, P., 1997, New and classical risk factors--the Münster heart study (PROCAM), European J. Med. Res., 2(6), 237-242.
  2. Berge, K., Robertson, B., Burri, L., 2015, Safety assessment of SuperbaTM krill powder: Subchronic toxicity study in rats, Toxicol. Rep., 2, 144-151. https://doi.org/10.1016/j.toxrep.2014.11.011
  3. Frost, R. J., Otto, C., Geiss, H. C., Schwandt, P., Parhofer, K. G., 2001, Effects of atorvastatin versus fenofibrate on lipoprotein profiles, low-density lipoprotein subfraction distribution, and hemorheologic parameters in type 2 diabetes mellitus with mixed hyperlipoproteinemia, Am. J. Cardiol., 87(1), 44-48. https://doi.org/10.1016/S0002-9149(00)01270-4
  4. Gigliotti, J. C., Davenport, M. P., Beamer, S. K., Tou, J. C., Jaczynski, J., 2011, Extraction and characterisation of lipids from antarctic Krill (Euphausia superba), Food Chem., 125(3), 1028-1036. https://doi.org/10.1016/j.foodchem.2010.10.013
  5. Izumi-Nagai, K., Nagai, N., Ohgami, K., Satofuka, S., Ozawa, Y., Tsubota, K., Ohno, S., Olike, Y., Ishida, S., 2008, Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin, Investigative Ophthalmol. Visual Sci., 49(4), 1679-1685. https://doi.org/10.1167/iovs.07-1426
  6. Kim, D. S., Do, J. R., Park, I. S., Rhee, S. K., 2000, Study on the manufacturing of chitosan using Krill (Euphausia superba Dana) and quality characteristics, J. Kor. Soc. Appl. Biol. Chem., 43(4), 309-313.
  7. Kim, H. S., 2006, Effects of the Saururus chinensis Baill hot-water extract intake on the lipid components and metabolic enzyme activities in hyperlipidemic rats, Kor. J. Exercise Nutr., 10(2), 99-106.
  8. Kim, H. S., Kim, M. A., Duan, Y., Jang, S. H., Kang, D. S., Lee, W. K., Lee, C. S., Ryu, J. Y., 2014, Fatty acid compositions, mineral and vitamin contents of the antarctic Krill (Euphausia superba), J. Environ. Sci. Int., 23(1), 47-52. https://doi.org/10.5322/JESI.2014.23.1.47
  9. Kim, H. S., Kim, M. A., Duan, Y., Kang, D. S., Jang, S. H., Ryu, J. Y., Lee, C. S., Lee, W. K., 2014, Studies on the nutritional components and amino acid compositions of krill (Euphausia superba), J. Environ. Sci. Int., 23(2), 165-170. https://doi.org/10.5322/JESI.2014.23.2.165
  10. Kim, H. S., Kim, M. A., Jang, S. H., 2014, Influences of Korean haw (Crataegus pinnatifida Bunge) on lipid concentration in hypercholesterolemia, J. Environ. Sci. Int., 23(5), 793-800. https://doi.org/10.5322/JESI.2014.5.793
  11. Kim, H. S., Seong, J. H., Lee, Y. G., Xie, C. L., Choi, W. S., Kim, S. H., Yoon, H. D., 2009, Effect of low-molecular-weight collagen peptide extract isolated from scales of the Flathead Mullet (Mugil cephalus) on lipid metabolism in hyperlipidemic rats, Kor. J. Food Preserv., 16(6), 938-945.
  12. Kim, H. S., Yoon, H. D., 2008, Effects of the chitosan oligosaccharide intake on the improvement of serum lipid level in hypercholesterolemic rats, J. Life Sci., 18(12), 1686-1692. https://doi.org/10.5352/JLS.2008.18.12.1686
  13. Kim, K. A., 2009, Understanding and application of liver function tests, Kor. J. Med., 76(2), 163-168.
  14. Kim, Y. J., 2008, Interpretation of liver function test, Korean J. Gastroenterol., 51(4), 219-224.
  15. Lee, K. H., Yoon, S. Y., Kim, H. K., 2000, Effect of crab shell powder on lipid metabolism in diet-induced hyperlipidemic rats, J. Kor. Soc. Food Sci. Nutr., 29(3), 453-459.
  16. Lee, M. F., Lai, C. S., Cheng, A. C., Hou, J. S., Badmaev, V., Ho, C. T., Pan, M. H., 2015, Krill oil and xanthigen separately inhibit high fat diet induced obesity and hepatic triacylglycerol accumulation in mice, J. Funct. Foods, 19, 913-921. https://doi.org/10.1016/j.jff.2014.10.015
  17. Leebmann, J., Roseler, E., Julius, U., Heigl, F., Spitthoever, R., Heutling, D., Breitenberger, P., Maerz, W., Lehmacher, W., Heibges, A., Klingel, R., 2013, Lipoprotein apheresis in patients with maximally tolerated lipid lowering therapy, Lp (a)-Hyperlipoproteinemia and progressive cardiovascular disease: prospective observational multicenter study, Circulation, 128, 2567-2576. https://doi.org/10.1161/CIRCULATIONAHA.113.002432
  18. Muriuki, M., Purdie, N., Dumancas, G., 2012, Quantification of the major ${\omega}$-3, ${\omega}$-6 PUFAs using the Purdie assay and their ratios in different cholesterol types and the effects of gender and cholesterol on PUFA levels, Trends Anal. Chem., 31, 157-164. https://doi.org/10.1016/j.trac.2011.10.005
  19. Rhee, S. K., Kim, D. S., 1999, The effective utilization techniques of Krill resources in antarctic ocean as new protein food, J. Kor. Prof. Eng. Assoc., 32(1), 90-98.
  20. Robertson, B., Burri, L., Berge, K., 2014, Genotoxicity test and subchronic toxicity study with SuperbaTM Krill oil in rats, Toxicol. Rep., 1, 764-776. https://doi.org/10.1016/j.toxrep.2014.07.007
  21. Shon, M. Y., Chung, M. H., Park, S. K., Cho, Y. S., 1994, Effects of krill and cadmium on lipid composition of plasma in cholesterol-fed rats, J. Kor. Soc. Food Sci. Nutr., 23(1), 38-43.
  22. Suh, H. L., Kim, S. A., Soh, H. Y., 1991, Distribution and abundance of the antarctic Krill (Euphausia superba) : A brief overview, Kor. J. Polar Res., 2(2), 29-49.
  23. Williams, K., Tchernof, A., Hunt, K. J., Wagenknecht, L. E., Haffner, S. M., Sniderman, A. D., 2008, Diabetes, abdominal adiposity, and atherogenic dyslipoproteinemia in women compared to men. Diabetes., 57(12), 3289-3296. https://doi.org/10.2337/db08-0787
  24. Yoshitomi, B., Aoki, M., Oshima, S., 2007, Effect of total replacement of dietary fish meal by low fluoride Krill (Euphausia superba) meal on growth performance of rainbow trout (Oncorhynchus mykiss) in fresh water, Aquaculture, 266(1), 219-225. https://doi.org/10.1016/j.aquaculture.2006.12.043