Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
권호 표지
DOI QR코드

DOI QR Code

Fusion Research in the Association of Lung Function with Pulse Pressure and Blood Lipid in Adults

성인의 맥압과 혈청지질 및 폐기능의 관계 융합 연구

  • Jo, Yoon-Kyung (Department of Clinical Laboratory Science, Dongnam Health University) ;
  • Sung, Hyun-Ho (Department of Clinical Laboratory Science, Dongnam Health University)
  • 조윤경 (동남보건대학교 임상병리과) ;
  • 성현호 (동남보건대학교 임상병리과)
  • Received : 2018.09.10
  • Accepted : 2018.11.20
  • Published : 2018.11.28
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to investigate whether there is a relationship between pulmonary function, serum lipid and pulse pressure, which is a risk factor of cardiovascular disease, in subjects with 109 office workers(51 males and 58 females) be at Seoul, Korea. The mean age of the subjects was $43.44{\pm}7.23$ years old (male $43.44{\pm}7.27$, fenale $49.1{\pm}11.5$). The subjects' height, weight, BMI, systolic and diastolic blood pressures were measured and there was statistical difference between men and women.The mean pulse pressure of the subjects was $47.82{\pm}9.02mmHg$, and the mean of FVC was $84.26{\pm}9.91%$. There was no difference between men and women in both. There was a positive correlation between pulse pressure and systolic blood pressure in males (p<0.01) and females (p<0.01), and FVC and HDL in males were positively correlated (p<0.05). Pulse pressure and %FVC were negatively correlated (r =-0.267, P<0.01). Pulse pressure and %FVC were negatively correlated (r =-0.267, P<0.01). Regression analysis showed that PP was the independent affected %FVC. Therefore, pulse pressure and %FVC may be useful as a predictor of cardiovascular disease in middle-aged subjects with normal, suggest a long-term convergence follow-up is warranted to elucidate the incidence of cardiovascular disease.

본 연구는 심혈관질환의 위험인자인 맥압과 혈청지질 그리고 폐기능 사이의 연관성이 존재하는지를 융합적으로 연구하고자 서울에 위치한 일개 회사의 사무직 종사자 109명(남성 51명, 여성 58명)을 대상으로 진행하였다. 대상자의 평균 연령은 $43.44{\pm}7.23$세, 남성 $43.44{\pm}7.27$세, 여성 $49.1{\pm}11.5$세였고, 키와 체중, BMI, 수축기혈압과 이완기 혈압을 측정하였고, 남녀의 차이가 있었다. 대상자의 맥압 평균은 $47.82{\pm}9.02mmHg$로 남녀의 차이는 없었다. %FVC의 평균은 $84.26{\pm}9.91%$로 남녀의 차이는 없었다. 맥압과 수축기혈압에서 남성(p<0.01), 여성(p<0.01)과 양의 상관관계를 나타내었으며, 남성에게서 FVC와 HDL는 양의 상관관계로 나타났다(p<0.05). 맥압과 %FVC는 음의 상관관계로 나타났다(-0.267, P<0.01). 회귀분석 결과 R2 은 0.071 로 맥압이 %FVC에 영향을 미치는 것으로 나타났다. 따라서, 혈압 측정에서의 맥압과 폐기능 검사는 심혈관계질환의 예측인자로 유용성이 있을 것으로 사료되며, 향후 심혈관질환의 연구의 융복합 연계가 필요할 것이다.

Keywords

Table 1. General characteristics of study population

OHHGBW_2018_v9n11_203_t0001.png 이미지

Table 2. Serum lipids of study population

OHHGBW_2018_v9n11_203_t0002.png 이미지

Table 3. Lung function of study population

OHHGBW_2018_v9n11_203_t0003.png 이미지

Table 4. Correlation of pulse pressure, serum lipid and FVC according to gender

OHHGBW_2018_v9n11_203_t0004.png 이미지

Table 5. Correlation of pulse pressure, serum lipid and %FVC by study population

OHHGBW_2018_v9n11_203_t0005.png 이미지

Table 6. Regression of pulse pressure to %FVC by study population

OHHGBW_2018_v9n11_203_t0006.png 이미지

References

  1. H. Yun, H. J. Oh, C. W. Choi. (2013). The association of pulse pressure and t-score. Joural of the Korea Entertainment Industry Association, 7(1), 166-173. https://doi.org/10.21184/jkeia.2013.03.7.1.166
  2. S. Y. Liaw, A. Scherpbier, P. Klainin-Yobas, J. J. Rethans. (2011). A review of educational strategies to improve nurses' roles in recognizing and responding to deteriorating patients. International Nursing Review, 58(3), 296-303. https://doi.org/10.1111/j.1466-7657.2011.00915.x
  3. J. W. Lee. (2002). Pulse pressure and systolic blood pressure. Korean Circulation J, 32(4), 293-298. https://doi.org/10.4070/kcj.2002.32.4.293
  4. S. Bangalore, F. H. Messerli, S. S. Franklin, G. Mancia, A. Champion, C. J. Pepine. (2009). Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis. European heart journal, 30(11), 1395-1401. https://doi.org/10.1093/eurheartj/ehp109
  5. S. Y. Kwon, Y. A. Na. (2016). The assessment of framingham risk score and 10 year CHD risk according to application of LDL cholesterol or total Cholesterol. Korean J Clin Lab Sci, 48, 54-61. https://doi.org/10.15324/kjcls.2016.48.2.54
  6. D. D. Sin, L. Wu, S. P. Man. (2005). The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literature. Chest, 127(6), 1952-1959. https://doi.org/10.1378/chest.127.6.1952
  7. D. A. Kaminsky, P. D. Savage, P. W. Callas, P. A. Ades. (2010). Lung function and cardiovascular risk: effect of cardiac rehabilitation. J Cardiopulm Rehabil Prev, 30(6), 384-90. https://doi.org/10.1097/HCR.0b013e3181d6f976
  8. C. E. Bolton, J. R. Cockcroft, R. Sabit, M. Munnery, C. M. McEniery, I. B. Wilkinson, Y. Ben-Shlomo. (2009). Lung function in mid-life compared with later life is a stronger predictor of arterial stiffness in men: the Caerphilly Prospective Study. Int J Epidemiol, 38(3), 867-876. https://doi.org/10.1093/ije/dyn374
  9. B. H. Jin, S. Y. Park. (2005). Correlations between Body Indices and FEV1 in Pulmonary Function Test. Korean J Clin Lab Sci, 37, 207-211.
  10. R. O. Crapo. (1994). Pulmonary-function testing. New England Journal of Medicine, 331(1), 25-30. https://doi.org/10.1056/NEJM199407073310107
  11. M. Zureik, A. Benetos, C. Neukirch, D. Courbon, K. Bean, F. Thomas, P. DucimetiEre. (2001). Reduced pulmonary function is associated with central arterial stiffness in men. American journal of respiratory and critical care medicine, 164(12), 2181-2185. https://doi.org/10.1164/ajrccm.164.12.2107137
  12. A. W. Haider, M. G. Larson, S. S. Franklin, D. Levy. (2003). Systolic blood pressure, diastolic blood pressure, and pulse pressure as predictors of risk for congestive heart failure in the Framingham Heart Study. Annals of internal medicine, 138(1), 10-16. https://doi.org/10.7326/0003-4819-138-1-200301070-00006
  13. S. W. Lee, E. S. Koo, B. S. Kim, J. H. Kang, M. H. Lee, J. R. Park, H. C. Shin, H. W. Jung, H. S. Lee. (1998). The Relationships between Blood Pressure and Serum Lipids in Korean Adults. Korean Circulation J, 28(9), 1552-1560. https://doi.org/10.4070/kcj.1998.28.9.1552
  14. E. J. Park, Y. A. Kim, D. S. Lim, M. S. Gee, S. W. You, H. Y. Woo. (2005). Comparison of hs-CRP and Lipid Values Between Hypertensive and Normotensive Groups. Korean J Clin Lab Sci, 37, 185-189.
  15. J. W. Kim, D. H. Kim, J. H. Ahan, J. T. Kim. (2013). Relationship between pulmonary function and metabolic syndrome, body mass index, fat percentage, and fat mass. Korean J Obes, 22(3), 177-181. https://doi.org/10.7570/kjo.2013.22.3.177
  16. S. R. Kim, U. S. Choi, J. H, Choi, H. J. Koh. (2003). Association of Body Fat and Body mass index with Pulmonary function in Women in their forties. J Korean Acad Fam Med, 24(9), 827-832.
  17. D. D. Sin, S. F. Man. (2005). Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality. Proc Am Thorac Soc, 2, 8-11. https://doi.org/10.1513/pats.200404-032MS
  18. D. J. Hole, G. C. Watt, G. Davey-Smith, C. L. Hart C. R. Gillis, V. M. Hawthorne. (1996). Impaired lung function and mortality risk in men and women: findings from the Renfrew and Paisley prospective population study. BMJ , 313, 711-715. https://doi.org/10.1136/bmj.313.7059.711
  19. D. P. Tashkin, A. H. Coulson, V. A. M. Simmons, L. B. Bourque, S. Duann, H. Gong. (1987). Respiratory symptoms and lung function in habitual heavy smokers of marijuana alone, smokers of marijuana and tobacco, smokers of tobacco alone, and nonsmokers. American Review of Respiratory Disease, 135(1), 209-216.
  20. J. H. Kim, E. J. Hwang, S. H. Kim, H. R. Lee, D. C. Lee. (2006). The Relation of Pulse Pressure to Insulin-like Growth Factor (IGF)-1. J Korean Acad Fam Med, 27(3), 201-207.
  21. J. H. Lee. (2017). The Association between Total Body Fat and Serum Lipids Concentrations in College Students. Korean J Clin Lab Sci, 49, 233-238. https://doi.org/10.15324/kjcls.2017.49.3.233
  22. C. S. Kim, D. S. Kim. (2016). The Association between Excessive Daytime Sleepiness and Blood Pressure in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome. Korean J Clin Lab Sci, 48, 255-261. https://doi.org/10.15324/kjcls.2016.48.3.255
  23. H. H. Sung, C. E. Park. (2013). Correlation between Body Composition and Vital Capacity. Journal of KOEN, 48, 255-261. doi : 10.21184/jkeia.2013.12.7.4.217