Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Blood amino acids profile responding to heat stress in dairy cows

  • Guo, Jiang (College of Animal Science and Technology, Hunan Agricultural University) ;
  • Gao, Shengtao (State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences) ;
  • Quan, Suyu (State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences) ;
  • Zhang, Yangdong (State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences) ;
  • Bu, Dengpan (College of Animal Science and Technology, Hunan Agricultural University) ;
  • Wang, Jiaqi (College of Animal Science and Technology, Hunan Agricultural University)
  • Received : 2016.06.02
  • Accepted : 2017.02.19
  • Published : 2018.01.01
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Abstract

Objective: The objective of this experiment was to investigate the effects of heat stress on milk protein and blood amino acid profile in dairy cows. Methods: Twelve dairy cows with the similar parity, days in milk and milk yield were randomly divided into two groups with six cows raised in summer and others in autumn, respectively. Constant managerial conditions and diets were maintained during the experiment. Measurements and samples for heat stress and no heat stress were obtained according to the physical alterations of the temperature-humidity index. Results: Results showed that heat stress significantly reduced the milk protein content (p<0.05). Heat stress tended to decrease milk yield (p = 0.09). Furthermore, heat stress decreased dry matter intake, the concentration of blood glucose and insulin, and glutathione peroxidase activity, while increased levels of non-esterified fatty acid and malondialdehyde (p<0.05). Additionally, the concentrations of blood Thr involved in immune response were increased under heat stress (p<0.05). The concentration of blood Ala, Glu, Asp, and Gly, associated with gluconeogenesis, were also increased under heat stress (p<0.05). However, the concentration of blood Lys that promotes milk protein synthesis was decreased under heat stress (p<0.05). Conclusion: In conclusion, this study revealed that more amino acids were required for maintenance but not for milk protein synthesis under heat stress, and the decreased availability of amino acids for milk protein synthesis may be attributed to competition of immune response and gluconeogenesis.

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References

  1. Bernabucci U, Basirico L, Morera P, et al. Effect of summer season on milk protein fractions in Holstein cows. J Dairy Sci 2015;98:1815-27. https://doi.org/10.3168/jds.2014-8788
  2. Smith DL, Smith T, Rude BJ, Ward SH. Short communication: Comparison of the effects of heat stress on milk and component yields and somatic cell score in Holstein and Jersey cows. J Dairy Sci 2013;96:3028-33. https://doi.org/10.3168/jds.2012-5737
  3. Archer SC, Mc CF, Wapenaar W, Green MJ. Association of season and herd size with somatic cell count for cows in Irish, English, and Welsh dairy herds. Vet J 2013;196:515-21. https://doi.org/10.1016/j.tvjl.2012.12.004
  4. Baumgard LH, Wheelock JB, Sanders SR, et al. Postabsorptive carbohydrate adaptations to heat stress and monensin supplementation in lactating Holstein cows. J Dairy Sci 2011;94:5620-33.
  5. Wang JP, Bu DP, Wang JQ, et al. Effect of saturated fatty acid supplementation on production and metabolism indices in heat-stressed mid-lactation dairy cows. J Dairy Sci 2010;93:4121-7. https://doi.org/10.3168/jds.2009-2635
  6. Cowley FC, Barber DG, Houlihan AV, Poppi DP. Immediate and residual effects of heat stress and restricted intake on milk protein and casein composition and energy metabolism. J Dairy Sci 2015;98:2356-68.
  7. Flynn NE, Knabe DA, Mallick BK, Wu G. Postnatal changes of plasma amino acids in suckling pigs. J Anim Sci 2000;78:2369-75. https://doi.org/10.2527/2000.7892369x
  8. National Research Council. Effect of environment on nutrient requirement of domestic animals. Washington, DC: National Academy Press;1981.
  9. AOAC International. Official Methods of Analysis. 18th ed. Gaithersburg, MD: AOAC International; 2005.
  10. Matsubara C, Nishikawa Y, Yoshida Y, Takamura K. A spectrophotometric method for the determination of free fatty acid in serum using acyl-coenzyme A synthetase and acyl-coenzyme A oxidase. Anal Biochem 1983;130:128-33. https://doi.org/10.1016/0003-2697(83)90659-0
  11. Cheng JB, Bu DP, Wang JQ, et al. Effects of rumen-protected $\gamma$-aminobutyric acid on performance and nutrient digestibility in heat-stressed dairy cows. J Dairy Sci 2014;97:5599-607. https://doi.org/10.3168/jds.2013-6797
  12. Liu LL, He JH, Xie HB, et al. Resveratrol induces antioxidant and heat shock protein mRNA expression in response to heat stress in blackboned chickens. Poult Sci 2014;93:54-62. https://doi.org/10.3382/ps.2013-03423
  13. Zuo L, Christofi FL, Wright VP, et al. Intra- and extracellular measurement of reactive oxygen species produced during heat stress in diaphragm muscle. Am J Physiol-cell Physiol 2000;279:1058-66. https://doi.org/10.1152/ajpcell.2000.279.4.C1058
  14. Halliwell B, Chirico S. Lipid peroxidation: its mechanism, measurement, and significance. Am J Clin Nutr 1993;57:715S-24S. https://doi.org/10.1093/ajcn/57.5.715S
  15. Mujahid A, Akiba Y, Warden CH, Toyomizu M. Sequential changes in superoxide production anion carriers and substrate oxidation in skeletal muscle mitochondria of heat-stressed chickens. FEBS Lett 2007;581:3461-7. https://doi.org/10.1016/j.febslet.2007.06.051
  16. West JW. Effects of heat-stress on production in dairy cattle. J Dairy Sci 2003;86:2131-44. https://doi.org/10.3168/jds.S0022-0302(03)73803-X
  17. Scott RA, Bauman DE, Clark JH. Cellular gluconeogenesis by lactating bovine mammary tissue. J Dairy Sci 1976;59:50-6.
  18. De Rensis F, Scaramuzzi RJ. Heat stress and seasonal effects on reproduction in the dairy cow-a review. Theriogenology 2003;60:1139-51. https://doi.org/10.1016/S0093-691X(03)00126-2
  19. Cooksey RC, Jouihan HA, Ajioka RS, et al. Oxidative stress, ${\beta}$-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis. Endocrinology 2004;145:5305-12. https://doi.org/10.1210/en.2004-0392
  20. Haque N, Ludri A, Hossain SA, Ashutosh M. Alteration of metabolic profiles in young and adult Murrah buffaloes exposed to acute heat stress. Iran J Appl Anim Sci 2012;1:23-9.
  21. Wheelock JB, Rhoads RP, VanBaale MJ, Sanders SR, Baumgard LH. Effects of heat stress on energetic metabolism in lactating Holstein cows. J Dairy Sci 2010;93:644-55. https://doi.org/10.3168/jds.2009-2295
  22. Stahel P, Purdie NG, Cant JP. Use of dietary feather meal to induce histidine deficiency or imbalance in dairy cows and effects on milk composition. J Dairy Sci 2014;97:439-45. https://doi.org/10.3168/jds.2013-7269
  23. Ai Y, Cao Y, Xie ZE, Zhang YS, Shen XZ. Relationship between free amino acids in cow's blood and decreasing milk protein under heat stress. Food Sci 2015;11:38-41.
  24. Meijer AJ. Amino acids as regulators and components of nonproteinogenic pathways. J Nutr 2003;133:2057S-62S. https://doi.org/10.1093/jn/133.6.2057S
  25. Wu G. Amino acids: metabolism, functions, and nutrition. Amino Acids 2009;37:1-17.
  26. Nan XM, Bu DP, Li XY, et al. Ratio of lysine to methionine alters expression of genes involved in milk protein transcription and translation and mTOR phosphorylation in bovine mammary cells. Physiol Genomics 2014;46:268-75. https://doi.org/10.1152/physiolgenomics.00119.2013
  27. Burgos SA, Dai M, Cant JP. Nutrient availability and lactogenic hormones regulate mammary protein synthesis through the mammalian target of rapamycin signaling pathway. J Dairy Sci 2010;93:153-61. https://doi.org/10.3168/jds.2009-2444
  28. Koch F, Lamp O, Eslamizad M, Weitzel J, Kuhla B. Metabolic response to heat stress in late-pregnant and early lactation dairy cows: implications to liver-muscle crosstalk. PloS one 2016;11:e0160912. https://doi.org/10.1371/journal.pone.0160912
  29. Naderi N, Ghorbani GR, Sadeghi-Sefidmazgi A, Nasrollahi SM, Beauchemin KA. Shredded beet pulp substituted for corn silage in diets fed to dairy cows under ambient heat stress: feed intake, totaltract digestibility, plasma metabolites, and milk production. J Dairy Sci 2016;99:8847-57. https://doi.org/10.3168/jds.2016-11029
  30. Chen KH, Huber JT, Theurer CB, et al. Effect of protein quality and evaporative cooling on lactational performance of Holstein cows in hot weather. J Dairy Sci 1993;76:819-25. https://doi.org/10.3168/jds.S0022-0302(93)77406-8

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