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다한증 환자의 사상의학적 특성에 관한 연구

A Clinical Analysis of Hyperhidrosis Patients in Korea: A Single Center, Retrospective Study of 5 Years

  • 오현주 (강동경희대학교병원 사상체질과) ;
  • 박민영 (강동경희대학교병원 사상체질과) ;
  • 전현진 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 황민우 (경희대학교 한의과대학 사상체질과)
  • Oh, Hyunjoo (Dept. of Sasang Constitutional Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Park, Minyoung (Dept. of Sasang Constitutional Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Jeon, Hyeonjin (Cancer Center, Kyung Hee University Hospital at Gangdong, College of Korean Medicine, Kyung Hee University) ;
  • Hwang, Minwoo (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University)
  • 투고 : 2018.11.08
  • 심사 : 2018.12.21
  • 발행 : 2018.12.31

초록

Objectives The purpose of this study was to analyze the clinical characteristics of patients with hyperhidrosis who visited a Korean medicine hospital, and provide information on treated hyperhidrosis, based on Sasang Constitutional medicine. Methods A retrospective review was made of the electronic medical record (EMR) charts for 157 Korean patients with hyperhidrosis (90 male, 67 female), who first visited hospital from January 1, 2013 to December 31, 2017. The following information was collected: sex, age, height, weight, body mass index (BMI) and clinical data (diagnosis, area of onset, duration of illness, aggravating factors, medication, healing process, et al). Results There were many patients with hyperhidrosis, in the other of So-Yang type (57.3%), Tae-Eum type (35.0%) and So-Eum type (7.6%). The proportion of male was higher than female. The most common area of hyperhidrosis was hands and feet (44.0%), followed by generalized whole body (27.4%) and head and face (25.5%). The cure rate of hyperhidrosis was 32.2%, and effectiveness rate of that was 72.7%. In individual patients, the better the usual health condition expressed by original symptoms, the higher the possibility of treatment success, with shortened duration of treatment and reduced total drug dose. The most frequent treatment modality in patients was that consistently improved, and this duration of treatment was statistically significantly shorter than that experienced worsening of excessive sweating during treatment period (p<0.001). Conclusions This study provides some original information on the Korean patients with hyperhidrosis, and suggests the suitability of Sasang Constitutional medicine as treatment methods for hyperhidrosis.

키워드

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Figure 1. Treatment success rate by age

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Figure 2. Treatment success rate by location

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Figure 3. Treatment success rate of So-Yang patients

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Figure 4. Treatment success rate of Tae-Eum patients

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Figure 5. Treatment success rate of So-Eum patients

Table 2. General Characteristics of Patients by Sasang Type

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Table 1. General Characteristics of Total Patients

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Table 3. Clinical Findings of Patients by Sasang Type

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Table 4. Clinical Distribution of Patients by Age

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Table 5. Clinical Distribution of Patients by Location

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Table 6. Clinical Distribution and Prescribed Medications of So-Yang Patients

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Table 7. Clinical Distribution and Prescribed Medications of Tae-Eum Patients

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Table 8. Clinical Distribution and Prescribed Medications of So-Eum Patients

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Table 9. Clinical Distribution of Patients by Healing Process

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참고문헌

  1. Walling HW and Swick BL. Treatment options for hyperhidrosis. Am J Clin Dermatol. 2011;12:285-295. https://doi.org/10.2165/11587870-000000000-00000
  2. Solish N, Bertucci V, Dansereau A, Hong HC, Lynde C, Lupin M, et al. Canadian Hyperhidrosis Advisory Committee. A comprehensive approach to the recognition, diagnosis, and severity-based treatment of focal hyperhidrosis: recommendations of the Canadian Hyperhidrosis Advisory Committee. Dermatol Surg. 2007;33:908-923.
  3. Park EJ, Han KR, Choi H, Kim DW and Kim C. An Epidemiological Study of Hyperhidrosis Patients Visiting the Ajou University Hospital Hyperhidrosis Center in Korea. J Korean Med Sci. 2010;25:772-775. https://doi.org/10.3346/jkms.2010.25.5.772
  4. Lear W, Kessler E, Solish N and Glaser DA. An epidemiological study of hyperhidrosis. Dermatol Surg. 2007;33:69-75.
  5. Hoorens I and Ongenae K. Primary focal hyperhidrosis: current treatment options and a step-by-step approach. J Eur Acad Dermatol Venereol. 2012;26:1-8.
  6. Letada PR, Landers JT, Uebelhoer NS and Shumaker PR. Treatment of focal axillary hyperhidrosis using a long pulsed Nd: YAG 1064 nm laser at hair reduction settings. J Drugs Dermatol. 2012;11:59-63.
  7. Hong HC, Lupin M and O'Shaughnessy KF. Clinical evaluation of a microwave device for treating axillary hyperhidrosis. Dermatol Surg. 2012;38:728-735. https://doi.org/10.1111/j.1524-4725.2012.02375.x
  8. Streker M, Reuther T, Hagen L, and Kerscher M. Hyperhidrosis pantaris-a randomized, half-side trial for efficacy and safety of an antiperspirant containing different concentrations of aluminium chloride. J Dtsch Dermatol Ges. 2012;10:115-119.
  9. Doft MA, Hardy KL and Ascherman JA. Treatment of hyperhidrosis with bodulinum toxin. Aesthet Surg J. 2012;32:238-244. https://doi.org/10.1177/1090820X11434506
  10. Benson RA, Palin R, Holt PJE and Loftus IM. Diagnosis and management of hyperhidrosis. Brit Med J. 2013;347:f6800. https://doi.org/10.1136/bmj.f6800
  11. Lee JH and Lee JC. Clinical Outcomes of Thoracic Sympathicotomy for Palmar Hyperhidrosis. Korean J Thorac Cardiovasc Surg. 2008;41:89-94. (Korean)
  12. Amini M, Harmsze AM and Tupker RA. Patient's estimation of efficacy of various hyperhidrosis treatments in a dermatological clinic. Acta Derm Venereol. 2008;88:356-362.
  13. Health Insurance Review and Assessment Service. Healthcare Bigdata Hub. Available from:URL:http://opendata.hira.or.kr/op/opc/olap3thDsInfo.do
  14. Finaly AY and Khan GK. Dermatology Life Quality Index(DLQI): A simple practical measure dor routine clinical use. Clin Exp Dermatol. 1994;19:210-216. https://doi.org/10.1111/j.1365-2230.1994.tb01167.x
  15. Swartling C, Naver H and Lindberg M. Botulinum A tocin improves life quality in severe primary focal hyperhidrosis. Eur J Neurol. 2001;8(3):247-252. https://doi.org/10.1046/j.1468-1331.2001.00207.x
  16. Campanati A, Penna L, Guzzo T, Menotta L, Silvestri B, Lagalla G, et al. Quality-of-life assessment in patients with hyperhidrosis before and after treatment with botulinum toxin: results of an open-label study. Clin Ther. 2003;25(1):298-308. https://doi.org/10.1016/S0149-2918(03)90041-5
  17. Innocenzi D, Lupo F, Bruni F, Frasca M, Panetta C and Milani M. Efficacy of a new aluminium salt thermophobic foam in the treatment of axillary and palmar primary hyperhidrosis: a pilot exploratory trial. Curr Med Res Opin. 2005;21(12):1949-1953. https://doi.org/10.1185/030079905X74899
  18. Bechara FG, Gamvichler T, Bader A, Sand M, Altmeyer P and Hoffmann K. Assessment of quality of life in patients with primary axillary hyperhidrosis before and after suction-curettage. J Am Acad Dermatol. 2007;15:1-6.
  19. Kim KI, Lee HB, Choi KH, Jung SK and Jung HJ. A Case Series Report on 11 Patients of Primary Palmar/Plantar Hyperhidrosis in Children and Adolescents Treated with Hospitalization Program of a Hyperhidrosis Clinic. Korean J Orient Int Med. 2012;33(3):327-337. (Korean)
  20. Cheshire WP and Freeman R. Disorders of sweating. Semin Neurol. 2003;23:399-406. https://doi.org/10.1055/s-2004-817724
  21. Hornberger J, Grimes K, Naumann M, Glaser DA, Lowe NJ, Naver H, et al. Recognition, diagnosis, and treatmend of primary focal hyperhidrosis. J Am Acad Dermatol. 2004;51:274-286. https://doi.org/10.1016/j.jaad.2003.12.029
  22. Eisenach JH, Atkinson JL and Fealey RD. Hyperhidrosis: evolving therapies for a well-established phenomenon. Mayo Clin Proc. 2005;80:657-666. https://doi.org/10.4065/80.5.657
  23. Kim YK, Lee JW, Park HJ, Shim HA, Choi CM and Won JH. A Case Report of Hyperhidrosis of palms, solies and axillae Treated with Bokryungbosimtanggamibang. Korean J Orient Int Med. 2005;26(4):897-903. (Korean)
  24. Yeon KJ, Kim CH and Roh SS. The Effect of Yangshimtang-Gamibang on 4 Cases of Hyperhidrosis of the Palms and Soles. J Korean Med Ophthalmol Otolaryngol Dermatol. 2005;18(3):135-141. (Korean)
  25. Lee HW and Hong SU. The Effect of Bakhotang-gamibang on 3 Cases of Hyperhidrosis of the Palms and Soles. J Korean Med Ophthalmol Otolaryngol Dermatol. 2006;19(2):256-262. (Korean)
  26. Kim KI, Lee HBM Choi KH, Jung SK and Jung HJ. A Case Series Report on 11 Patients of Primary Palmar/Plantar Hyperhidrosis in Children and Adolescents Treated with Hospitalization Program of a Hyperhidrosis Clinic. J Int Korean Med. 2012;33(3):327-337. (Korean)
  27. Park JM, Choi SW and Chae JW. A Case Report of Hands and Feet Hyperhidrosis. J Pediatr Korean Med. 2013;27(4):68-76. (Korean) https://doi.org/10.7778/jpkm.2013.27.4.068
  28. Lee BY, Lee HJ, Kim JH, Choi HY, Kim YJ, Cho SY, et al. The Efficacy of Shihogayonggolmoryo-tang in Combating Excessive Sweating in Heart Disease Syndrome, Called 心病 in Korean Medicine. J Int Korean Med. 2016;37(4):601-608. (Korean) https://doi.org/10.22246/jikm.2016.37.4.601
  29. Hwang MW. Lecture of Sasang Constitutional Medicine (1st ed). Seoul:Koonja Publishing. 2012:202. (Korean)
  30. Hong SM, Lee SY and Hwang MW. A Case Study of Soyangin Patient with Hyperhidrosis Treated Successfully with Hyungbangsabaek-san. J Sasang Constitut Med. 2014;26(4):379-388. (Korean) https://doi.org/10.7730/JSCM.2014.26.4.379
  31. Lee JH and Shin MR. The Study of the Hyperhidrosis Patient Treated with Yanggyuksanhwa-tang. J Sasang Constitut Med. 2011;23(4):526-532. (Korean) https://doi.org/10.7730/JSCM.2011.23.4.526
  32. Kim JH, Shin DY, Choi DS, Kang SI and Song JM. A Case Study of Three Patients who have the idiopathic Excessive sweating on palm and sole. J Sasang Constitut Med. 2004;16(2):122-127. (Korean)