The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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A Clinical Research about Herbal Cosmetics Containing Caffeic acid phenethyl ester Isolated from Vespae Nidus on the Whitening Effects

노봉방에서 추출된 카페인산 페네틸 에스테르가 함유된 한방화장품의 미백 개선에 관한 임상적 연구

  • Cha, Ho-Yeol (Department of Pediatrics of Korean Medicine, Pusan National University Hospital) ;
  • Kim, Hee-Yeon (Department of Pediatrics of Korean Medicine, Pusan National University Hospital) ;
  • Ha, Ki-Tae (School of Korean Medicine, Pusan National University) ;
  • Cheon, Jin-Hong (Department of Pediatrics of Korean Medicine, Pusan National University Hospital) ;
  • Kim, Kibong (Department of Pediatrics of Korean Medicine, Pusan National University Hospital)
  • 차호열 (부산대학교 한방병원 한방소아과) ;
  • 김희연 (부산대학교 한방병원 한방소아과) ;
  • 하기태 (부산대학교 한의학전문대학원) ;
  • 천진홍 (부산대학교 한방병원 한방소아과) ;
  • 김기봉 (부산대학교 한방병원 한방소아과)
  • Received : 2017.08.16
  • Accepted : 2017.09.18
  • Published : 2017.09.30
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Abstract

Objectives: The purpose of this clinical research was to investigate the effects of herbal cosmetics containing Caffeic acid phenethyl ester (CAPE), an ingredient compound of various herbs including Vespae Nidus, on the Whitening Effects. Methods: A total of 20 subjects who visited Pusan National University Hospital from March 2nd, 2017 to April 11th, 2017 were included. In this study, we evaluated the visual evaluation, the melanin index (M) and erythema index (E) through skin analysis equipment, the subjective whitening improvement analysis, and the adverse reaction according to product use. Statistical analysis was performed with independent t-test and Mann-Whitney's U test. Statistical significance was achieved if the probability was less than 5% (p<0.05) Results: As a result of the visual evaluation, it was effective in improving skin whitening. The subjective whitening improvement analysis also showed positive results. However, no statistically significant differences were found between the test and control cosmetics in the melanin index (M) and erythema index (E) through skin analysis equipment. In the safety evaluation, some adverse reactions were reported, but no significant were observed directly from cosmetics. Conclusions: Considering the above results, we have confirmed the possibility of herbal cosmetics containing containing CAPE of Vespae Nidus Extracts.

Keywords

References

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