Deep Benign Fibrous Histiocytoma Showing Multiple Metastases

다발성 전이를 동반한 심부 양성 섬유조직구종

  • Sim, Hyun Bo (Department of Dermatology, Kyungpook National University School of Medicine) ;
  • Kim, Min Ji (Department of Dermatology, Kyungpook National University School of Medicine) ;
  • Chae, Soo Yuhl (Department of Dermatology, Kyungpook National University School of Medicine) ;
  • Lee, Weon Ju (Department of Dermatology, Kyungpook National University School of Medicine) ;
  • Lee, Seok-Jong (Department of Dermatology, Kyungpook National University School of Medicine) ;
  • Kim, Do Won (Department of Dermatology, Kyungpook National University School of Medicine) ;
  • Jang, Yong Hyun (Department of Dermatology, Kyungpook National University School of Medicine)
  • 심현보 (경북대학교 의학전문대학원 피부과학교실) ;
  • 김민지 (경북대학교 의학전문대학원 피부과학교실) ;
  • 채수열 (경북대학교 의학전문대학원 피부과학교실) ;
  • 이원주 (경북대학교 의학전문대학원 피부과학교실) ;
  • 이석종 (경북대학교 의학전문대학원 피부과학교실) ;
  • 김도원 (경북대학교 의학전문대학원 피부과학교실) ;
  • 장용현 (경북대학교 의학전문대학원 피부과학교실)
  • Received : 2015.10.28
  • Accepted : 2016.05.03
  • Published : 2017.06.30


Some morphological variants of benign fibrous histiocytoma (dermatofibroma) present with distinct clinical features. In particular, atypical, aneurysmal, and cellular fibrous histiocytoma are associated with a significant risk of local recurrence. Furthermore, very rarely, cutaneous fibrous histiocytoma can lead to metastatic disease. Deep benign fibrous histiocytoma is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue. Deep benign fibrous histiocytoma has many histologic features in common with cellular fibrous histiocytoma. Deep benign fibrous histiocytoma recurs in approximately 20% of cases and may rarely metastasize. We report a rare case of deep benign fibrous histiocytoma with metastatic potential in a 38-year-old man who presented with a 2-year history of a recurrent hard mass on his left shoulder.


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