Journal of Food Hygiene and Safety (한국식품위생안전성학회지)

The Korean Society of Food Hygiene and Safety (한국식품위생안전성학회)
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Analytical Method of Silicon Dioxide in Health Functional Food Products using ICP-OES

  • Ka, Mi-Hyun (Korea Health Supplements Association Sub. Korea Health Supplements Institute) ;
  • Lee, Kwang-Geun (Department of Food Science and Biotechnology, Dongguk University Biomedi Campus) ;
  • Lim, Heung-Youl (Korea Health Supplements Association Sub. Korea Health Supplements Institute) ;
  • Lee, Gunyoung (Food Additives and Packaging Division, National Institute of Food and Drug Safety Evaluation) ;
  • Yun, Sang Soon (Food Additives and Packaging Division, National Institute of Food and Drug Safety Evaluation) ;
  • Lim, Ho Soo (Food Additives and Packaging Division, National Institute of Food and Drug Safety Evaluation) ;
  • Kim, Yong-Suk (Department of Food Science & Technology, College of Agriculture and Life Sciences, Chonbuk National University)
  • Received : 2017.08.22
  • Accepted : 2017.09.15
  • Published : 2017.10.30
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Abstract

The analytical method of silicon dioxide ($SiO_2$) in health functional food products was developed employing inductively coupled plasma optical emission spectrometry (ICP-OES) method assisted by acid (hydrofluoric acid and boric acid) digestion in open system without alkali fusion. The limit of detection (LOD) and limit of quantification (LOQ) of this method were found to be 0.07 and 0.20 mg/L, respectively. Linearity ($r^2$) and linear range were 0.99 and 0.20~20.0 mg/L, respectively. The accuracy and precision of $SiO_2$ (0.4, 1.0, and 2.0%, w/w) in spiked glucosamine exhibited to be the range of 90.22~94.14% and 0.72~1.67%, respectively. The contents of $SiO_2$ in 11 health functional food products were detected in range of 0.02~1.80% (w/w). Every sample showed below content of the permitted use level (2%, w/w) of $SiO_2$. Therefore ICP-OES method with acid can analyze the content of $SiO_2$ in health functional food products easily and rapidly. Consequently, the application of specification analysis of $SiO_2$ in health functional food products could be a significant work.

건강기능식품에서 이산화규소 분석 방법을 확립하기 위하여 산(불산과 붕산)분해를 이용한 ICP-OES 방법을 수행하였다. 이 방법의 검출한계와 정량한계는 각각 0.07 mg/L, 0.20 mg/L 이었다. 검량선은 0.2~20.0 mg/L의 농도범위에서 우수한 직선성($r^2$ 0.99)을 보였다. 글루코사민 제품에 이산화규소 0.4, 1.0, 2.0% (w/w)를 첨가하여 시험한 결과 90.22~94.14%의 회수율과 0.72~1.67%의 정밀성을 나타내었다. 확립된 방법으로 시중에 유통되는 건강기능식품 11품목의 이산화규소 함량을 분석한 결과 0.02~1.80% (w/w)로 나타났다. 이 결과는 건강기능식품에 이산화규소의 사용기준 2% (w/w) 이하를 만족하는 결과로 시험한 제품들은 규격에 적합하였다. 따라서 본 연구에서 확립된 이 방법은 건강기능식품 중 이산화규소를 쉽고, 빠르게 분석할 수 있으며, 건강기능식품 중 이산화규소 함량 분석에 효율적으로 사용될 수 있다.

Keywords

References

  1. Joint FAO/WHO Expert Committee on Food Additives (JECFA, 2001). Silicon dioxide. Available from: http://www.fao.org/ag/agn/jecfaadditives/specs/Monograph1/Additive-385.pdf. Accessed Nov. 24, 2015.
  2. Joint FAO/WHO Expert Committee on Food Additives (JECFA, 2013). Silicon dioxide. Available from: http://www.fao.org/ag/agn/jecfaadditives/specs/monograph14/additive-385-m14.pdf. Accessed Nov. 24, 2015.
  3. Ministry of Food and Drug Safety (MFDS, 2015). Silicon dioxide. Available from: http://fa.kfda.go.kr/standard/egongjeon_standard_view.jsp?SerialNo=420&GoCa=1. Accessed Sep. 24, 2015.
  4. Ministry of Health, Labour and Welfare (MHLW, 2015). Available from: http://www.ffcr.or.jp/zaidan/FFCRHOME.nsf/7bd44c20b0dc562649256502001b65e9/8a4352b95978-b195492569990007fbaa/$FILE/Standards%20for%20Use%2015September%2018.pdf. Accessed Sep. 24, 2015.
  5. U.S. Food and Drug Administration (FDA) CFR-Code of Federal Regulation Title 21. Silicon dioxide. Available from: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.480&SearchTerm=silicon%20dioxide. Accessed Nov. 24, 2015.
  6. Food and Drug Administration (FDA). Generally recognized as safe determination for silicon dioxide when added directly and/or indirectly to human food. Available from: http://www.fda.gov/ucm/groups/fdagov-public/@fdagov-foods-gen/ documents/document/ucm269494.pdf. Accessed Nov. 24, 2015.
  7. Chesnokova S.M. and Lashuk E.P.: Determination of the concentration of silicon dioxide in crystal by potentiometic titration with a fluoride-selective electrode. Glass and Ceramics. 51, 3-4 (1994). https://doi.org/10.1007/BF00682528
  8. Myshkin S.N.: High-speed method of determining silicone dioxide in magnesite and dolomite. Refract. Ind. Ceram. 2, 191-192 (1961).
  9. Watanabe M, Otsuki S.: Highly precise determination of silica in silicate by alkali fusion/coagulation gravimetric method. Bunseki Kagaku. 57, 31-34 (2008). https://doi.org/10.2116/bunsekikagaku.57.31
  10. Mori. H.: Extraction of silicone dioxide from waste colored glasses by alkali fusion using potassium hydroxide. J. Mater Sci. 38, 3461-3468 (2003). https://doi.org/10.1023/A:1025100901693
  11. Mori. H.: Extraction of silicone dioxide from waste colored glasses by alkali fusion using sodium hydroxide. J. Ceram. Soc. Jpn. 111, 376-381 (2003). https://doi.org/10.2109/jcersj.111.376
  12. Akiyama K, Nakanishi T, Ohnishi R, Akagi T.: Dissolution method for the determination of silicon in plant samples with ICP-AES. Bunseki Kagaku. 53, 1229-1232 (2004). https://doi.org/10.2116/bunsekikagaku.53.1229
  13. Bernas B.: A new method for decomposition and comprehensive analysis of silicates by atomic absorption spectrometry. Anal. Chem. 40(11), 1682-1686 (1968). https://doi.org/10.1021/ac60267a017
  14. Motoh M, Kyoko S, Yoshichika H, Yoko K.: Analytical methods for $SiO_2$ and other inorganic oxides in titanium dioxide or certain silicate or certain silicates for food additive specifications. Food Addit. Contam. 28, 423-427 (2011). https://doi.org/10.1080/19440049.2010.551548