Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix

  • Maiorana, Carlo (Implant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan) ;
  • Poli, Pier Paolo (Implant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, IRCCS Ca Granda Ospedale Maggiore Policlinico Foundation, University of Milan) ;
  • Deflorian, Matteo (Section of Implant Dentistry and Oral Rehabilitation, Department of Biomedical, Surgical and Dental Sciences, Dental Clinic, IRCCS Galeazzi Orthopedic Institute, University of Milan) ;
  • Testori, Tiziano (Section of Implant Dentistry and Oral Rehabilitation, Department of Biomedical, Surgical and Dental Sciences, Dental Clinic, IRCCS Galeazzi Orthopedic Institute, University of Milan) ;
  • Mandelli, Federico (Dental School, Vita-Salute University and Department of Dentistry, IRCCS San Raffaele Hospital) ;
  • Nagursky, Heiner (Medical Center, University of Freiburg Institute for Clinical Chemistry and Laboratory Medicine) ;
  • Vinci, Raffaele (Dental School, Vita-Salute University and Department of Dentistry, IRCCS San Raffaele Hospital)
  • Received : 2017.05.16
  • Accepted : 2017.07.10
  • Published : 2017.08.30
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Abstract

Purpose: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. Methods: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure. Results: Clinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles ($31.97%{\pm}3.52%$) were surrounded by either newly formed bone ($16.02%{\pm}7.06%$) or connective tissue ($50.67%{\pm}8.42%$) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue. Conclusions: Socket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good reepithelialisation of the soft tissues during a 6-month healing period.

Keywords

References

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