References
- Kuang H, Cheng W. Studies on the capability of properties and flavors of Chinese Medicine to be split and combined-A new assumption on the theory of properties and flavors of Chinese Medicine and the research method. World Sci Technol/Moderniz Trad Chin Med Mater Med 2009;11:768-71.
- Park JY, Choi P, Lee D, Kim T, Jung EB, Hwang B-S, Kang KS, Ham J. Effect of amino acids on the generation of ginsenoside Rg3 epimers by heat processing and the anticancer activities of epimers in A2780 human ovarian cancer cells. Evid Based Compl Alt 2016;3:1-6.
- Sharma AM. Adipose tissue: a mediator of cardiovascular risk. Int J Obes Relat Metab Disord 2002;4:S5-7.
- Kong L, Wei Q, Fedail JS, Shi F, Nagaoka K, Watanabe G. Effects of thyroid hormones on the antioxidative status in the uterus of young adult rats. J Reprod Dev 2015;61:219-27. https://doi.org/10.1262/jrd.2014-129
- Choksi NY, Jahnke GD, St Hilaire C, Shelby M. Role of thyroid hormones in human and laboratory animal reproductive health. Birth Defects Res B Dev Reprod Toxicol 2003;68:479-91. https://doi.org/10.1002/bdrb.10045
- Jannini EA, Ulisse S, D'Armiento M. Thyroid hormone and male gonadal function. Endocr Rev 1995;16:443-9.
- Metz LD, Seidler FJ, McCook EC, Slotkin TA. Cardiac alpha-adrenergic receptor expression is regulated by thyroid hormone during a critical developmental period. J Mol Cell Cardiol 1996;28:1033-44. https://doi.org/10.1006/jmcc.1996.0096
- Krassas GE. Thyroid disease and female reproduction. Fertil Steril 2000;74:1063-70. https://doi.org/10.1016/S0015-0282(00)01589-2
- Chen H. Practical internal medicine. 11th ed. Beijing: People's Medical Publishing House (PMPH); 2001.
- Jia X. The study on the therapeutic mechanisms of the prescription warming the kidney and invigorating the spleen on rat's experimental hypothyroidism. Tianjin: Tianjin University of Traditional Chinese Medicine; 2007.
- Xu C, Xu D, Qu Z. Advances in research of the mechanism of hypothyroidism on the method of warmly invigorating kidney yang. Chin J Information on Trad Chin Med 2005;12:107-8.
- Chen Y. Combine traditional Chinese and western medicine treatment of 30 cases of primary hypothyroidism. Jilin J Trad Chin Med 2004;24:32-3.
- Chen W, Zhong M, Yang J. Treatment of hypothyroidism (type of yang-deficiency of spleen and kidney) by modified zhenwu tang: A clinical observation of 30 cases. New J Trad Chin Med 2006;38:41-2.
- Su J. 92 cases of Licorice root ginseng soup in the treatment of hypothyroidism disease. J Trad Chin Med 2002;43:448-9.
- Niu Y. TCM treatment progress of primary hypothyroidism. J Anhui Med Pharm 2010;14:352-5.
-
Xu X, Dou D. The ginseng's fireness is associated with the lowering activity of liver
$Na^+-K^+$ -ATPase. J Ethnopharmacol 2016;190:241-50. https://doi.org/10.1016/j.jep.2016.06.024 - Chinese Pharmacopoeia. Beijing: Chinese Medical Science and Technology Press (CMSTP); 2015.
- Xu SY, Bian RL, Chen X. Methodology of pharmacological experiment. 3rd ed. Beijing: People's Medical Publishing House (PMPH); 2002.
- Jing L, Yang Y, Yin C, Li R, Lin JJ. Experimental study on respiratory exchange ratio and heat production of rats with kidney-yang deficiency. J Shandong Univ TCM 2013;2:148-50.
- Wan S. Effects of levothyroxine and Vitamin E treatment on hippocampus oxidative stress level and apoptosis in hypothyroidism rats. Doctoral dissertation. Hefei: Anhui Medical University; 2013.
- Sawin CT, Geller A, Wolf PA, Belanger AJ, Baker E, Bacharach P, Wilson PWF, Benjamin EJ, D'Agostino RB. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med 1994;331:1249-52. https://doi.org/10.1056/NEJM199411103311901
- Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, Johnson TI, Gaude E, King A, Leach JDG, Edrada-Ebel R, et al. Fumarate induces redox-dependent senescence by modifying glutathione metabolism. Nat Commun 2015;23:1-12.
- Adam J, Yang M, Bauerschmidt C, Kitagawa M, O'Flaherty L, Maheswaran P, Ozkan G, Sahgal N, Baban D, Kato K, et al. A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia. Cell Rep 2013;3:1440-8. https://doi.org/10.1016/j.celrep.2013.04.006
- Oakhill JS, Steel R, Chen Z-P, Scott JW, Ling N, Tam S, Kemp BE. AMPK is a direct adenylate charge-regulated protein kinase. Science 2011;332:1433-5. https://doi.org/10.1126/science.1200094
-
Jaitovich A, Angulo M, Lecuona E, Dada LA, Welch LC, Cheng Y, Gusarova G, Ceco E, Liu C, Shigemura M, et al. High
$CO_2$ levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific ring finger protein 1 (MuRF1). J Biol Chem 2015;290:9183-94. https://doi.org/10.1074/jbc.M114.625715 - Xie X, Zhu Y. AMPK and metabolic syndrome. Basic Clin Med 2006;26:27-34.
- Winder WW, Hardie DG. AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am J Physiol 1999;277:1-10.
- Jenkins Y, Sun TQ, Markovtsov V, Foretz M, Li W, Nguyen H, Li Y, Pan A, Uy G, Gross L, et al. AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes. PLoS One 2013;8:1-19.
-
Einholm AP, Nielsen HN, Holm R, Toustrup-Jensen MS, Vilsen B. Importance of a potential protein kinase A phosphorylation site of
$Na^+$ ,$K^+$ -ATPase and its interaction network for$Na^+$ binding. J Biochem 2016;291:10934-47. - Goldberg ND. Advances in cyclic nucleotide research. New York: Raven Press; 1975.
- Zheng G, Zheng S. The theory of Yin and Yang with cyclic nucleotide. Chin J Nat 1979;2(4):208.
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