대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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청소년궤양성 대장염 환자의 사상체질요법에 대한 증례보고

Constitution Therapy of Adolescent Ulcerative Colitis: A Case Report

  • 박세기 (현등한의원) ;
  • 김근엽 (세명대학교 부속한방병원 내과학교실) ;
  • 신선미 (세명대학교 부속한방병원 내과학교실) ;
  • 고흥 (세명대학교 부속한방병원 내과학교실)
  • Park, Se-gi (Healing Light Korean Medicine) ;
  • Kim, Geun-yeob (Dept. of Korean Internal Medicine, Jaechon Oriental Hospital, Se-Myung University) ;
  • Shin, Seon-mi (Dept. of Korean Internal Medicine, Jaechon Oriental Hospital, Se-Myung University) ;
  • Ko, Heung (Dept. of Korean Internal Medicine, Jaechon Oriental Hospital, Se-Myung University)
  • 투고 : 2017.09.05
  • 심사 : 2017.09.20
  • 발행 : 2017.09.30
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초록

Objectives: This study discusses the effects of constitution therapy on adolescent ulcerative colitis. Methods: A 12-year-old male patient was treated with western medication for six months and herbal medicine for one year and six years; however, his abdominal pain, mucousy stool, bloody stool, and diarrhea persisted. He was diagnosed as having Taeumin according to Sasang constitution classification and treated with Sasang constitutional medicine (i.e., Yeuldahanso-tang and food restrictions based on constitutional medicine theory). Before the first treatment, his Pediatric Ulcerative Colitis Activity Index (PUCAI) score was 35, but this score decreased to 15 within six months and was maintained at 10 by 18 months of treatment. He took the herbal medication for 38 months, and his PUCAI score was 0 at the end of treatment. His liver functioned normally despite long-term drug use, and a follow-up colonoscopy showed no ulcerative colitis except melanosis, which was presumed to be caused by the herbal medicine. Ulcerative colitis in pediatric adolescents requires treatment with pharmacotherapy and dietary control based on constitutional medicine to maintain disease remission. Conclusions: Constitutional therapy is effective for treating adolescent ulcerative colitis. More clinical data are needed for patients with ulcerative colitis.

키워드

참고문헌

  1. Sato SS, Inoue TK. The pathophysiology of human body structure and function. 1st edition. Seoul: Gunja Publishing Co.; 2014, p. 51-8.
  2. Choi CH, Jung SA, Lee BI, Lee KM, Kim JS, Han DS, et al. Diagnostic Guideline of Ulcerative Colitis. Korean J Gastroenterol 2009;53(3):145-60.
  3. Bigyenaegwahagclassroom. Bigyenaegwahag. 1st edition. Seoul: Gunja Publishing Co.; 2008, p. 36-75.
  4. An JH, Choi EY, Lee SH, Park IS, Lim SW. Effect of of Hwangryunhaedoktang on DSS-induced colitis. J Korean Oriental Med 2006;27(2):182-95.
  5. Song YG, Ryu BH, Yun SW. The Effects of Soyumjungjang-tang on DSS-Induced Ulcerative Colitis in Mouse. Korean J Orient Int Med 2008;29(2):385-400.
  6. Heo G, Jang MW, Lim SW. The Effects of Coicis Semen Extract (CSE) on Dextran Sulfate Sodium. Korean J Orient Int Med 2012;33(4):520-32.
  7. Seo CH, Lee HH, Choi KS, Lim DS, Ryu HC, Lee YS, et al. Two Cases of Ulcerative Colitis Diagnosed as Damp-Heat Dysentery Treated with Jakyaktang-gamibang. Korean J Orient Int Med 2006;27(4):984-90.
  8. Yoon SW. A Case Report of a Patient with Active Ulcerative Colitis Treated with Do-Che Decoction-based Korean Medicine. J of Kor Traditional Oncology 2012;17(2):17-22.
  9. Lim DS, Kim NU, Lee HH, Hong S, Kim HC, Choi CW. One Case of Ulcerative Colitis Improved by Gagam-Sukhongjeon. The Korean J of Oriental medical prescription 2007;15(1):229-37.
  10. Park K, Cho DH, Kwak MA, Kim DJ, Byun JS. Case Report of Ulcerative Colitis Medicated by Danggwihwahyeolsan-gamibang and Gami- Jeonssibaekchulsan. The Korean J of Oriental medical prescription 2007;15(2):187-95.
  11. Kim J. Seongliimsanglon. 2nd edition. Seoul: Daeseongmunhwasa; 1998, p. 71.
  12. Alan L, David B, Nick B, Assad B, Sarah C, Balda F, at el. Ulcerative colitis: management. Manchester: NICE; 2013, p. 1-36.
  13. Porter SN, Howaeth GS, Butler RN. An orally administered growth factor extract derived from bovine whey suppresses breath ethane in colitic rats. Scand J of Gastroenterol 1998;33(9):967-74. https://doi.org/10.1080/003655298750027001
  14. Mosen U, Sorstad J, Hellers G, Johansson C. Extracolonic diagnoses in ulcerative colitis: an epidemiological study. Am J Gastroenterol 1990;85(6):711-6.
  15. Jeen YT, Kim JH. Advances in ulcerative colitis therapy. Korean J Med 2009;76(6):654-60.
  16. Ishiguro K, Ando T, Maeda O, Hasegawa M, Kadomatsu K, Ohmiya N, et al. Paeonol attenuates TNBS-induced colitis by inhibiting NF-B and STAT1 transactivation. Toxicol Appl Pharmacol. 2006;217(1):35-42. https://doi.org/10.1016/j.taap.2006.07.002
  17. Kim SY, Park JW, Ryu BH. Effects of Auklandialappa on dextran sulfate sodiuminduced murine colitis. Korean J Orient Int Med 2013;34(2):134-46.
  18. Ko BH, Koo DM, Kim KY, Kim DR, Kim IH, Kim JY, et al. Sasang Constitutional Medicine. 2nd edition. Seoul: Jipmoondang; 2004, p. 320-8.
  19. Lee KH, Yang J, Chang GT. A Psoriasis Case Report on Liver Damage Related to Scutellaria Radix. J Korean Oriental Med 2011;32(4):149-58.
  20. Yun YJ, Shin BC, Jang IS. Suggestion of Herbal Medicine-Induced Liver Injury investigation Forms for Improving the Research Quality of Herbal Safety. Korean J Orient Int Med 2009;30(1):181-90.
  21. Zhang Y, Du YP, Wang WY, Liu DP, Ma Q, Wang W. The Study on the Mechanism of Anthraquinone Herbs Caused by Melanosis Coli. Progress in Modern Biomedicine 2013;13(3):408-15.

피인용 문헌

  1. 한약치료를 통해 관해가 유도된 궤양성대장염 환자: 증례보고 vol.36, pp.3, 2017, https://doi.org/10.14406/acu.2019.014