Psychiatry investigation

Korean Neuropsychiatric Association (대한신경정신의학회)
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Clinical Validation of the Psychotic Depression Assessment Scale, Hamilton Depression Rating Scale-6, and Brief Psychiatric Rating Scale-5: Results from the Clinical Research Center for Depression Study

  • Park, Seon-Cheol (Department of Psychiatry, Inje University College of Medicine and Haeundae Paik Hospital) ;
  • Jang, Eun Young (Department of Counseling Psychology, Honam University College of Humanities and Social Sciences) ;
  • Kim, Jae-Min (Department of Psychiatry, Chonnam National University School of Medicine) ;
  • Jun, Tae-Youn (Department of Psychiatry, The Catholic University of Korea College of Medicine) ;
  • Lee, Min-Soo (Department of Psychiatry, Korea University College of Medicine) ;
  • Kim, Jung-Bum (Department of Psychiatry, Keimyung University School of Medicine) ;
  • Yim, Hyeon-Woo (Department of Preventive Medicine, The Catholic University of Korea College of Medicine) ;
  • Park, Yong Chon (Department of Psychiatry, Hanyang University, Guri Hospital)
  • Received : 2016.05.20
  • Accepted : 2016.08.15
  • Published : 2017.09.25
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Abstract

Objective The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the five-item psychosis subscale from the brief psychiatric rating scale (BPRS-5). Data from the Clinical Research Center for Depression (CRESCEND) study, which is a 52-week naturalistic trial, were analyzed. Methods Fifty-two patients with psychotic depression from the CRESCEND study met our inclusion criteria. The patients underwent the following psychometric assessments: the PDAS, including HAMD-6 and BPRS-5, the clinical global impression scales, the HAMD, the positive symptom subscale, and the negative symptom subscale. Assessments were performed at the baseline and then at weeks 1, 2, 4, 8, 12, 24, and 52. Spearman correlation analyses were used to assess the clinical validity and responsiveness of the PDAS. Results The clinical validity and responsiveness of the PDAS, including HAMD-6 and BPRS-5, were acceptable, with the exception of the clinical responsiveness of the PDAS for positive symptoms and the clinical responsiveness of BPRS-5 for negative symptoms. Conclusion The clinical relevance of the PDAS has been confirmed and this clinical validation will enhance its clinical utility and availability.

Keywords

Acknowledgement

Supported by : Korea Healthcare Technology

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