The Korean Journal of Vision Science (대한시과학회지)

The Korean Society of Vision Science (대한시과학회)
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Evaluation of Cellulose and Super-Absorbent-Polymer as an Absorbent of Tube-type Tear Test Kit

튜브형 눈물검사키트 흡수제로서 셀룰로오스와 고흡수성 폴리머의 유용성 평가

  • Park, Jung-Eun (Dept. of Optometry, Graduate School of Public Health, Eulji University) ;
  • Song, In-Chang (OccuTech, Co. LTD.) ;
  • Jeong, Myeong-Jin (Dept. of Environmental Health and Safety, Eulji University) ;
  • Lee, Koon-Ja (Dept. of Optometry, Graduate School of Public Health, Eulji University)
  • 박정은 (을지대학교 보건대학원 안경광학과) ;
  • 송인창 ((주)오큐텍) ;
  • 정명진 (을지대학교 보건환경안전학과) ;
  • 이군자 (을지대학교 보건대학원 안경광학과)
  • Received : 2017.11.02
  • Accepted : 2017.12.11
  • Published : 2017.12.31
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Abstract

Purpose: To evaluate the efficacy of cellulose (CEL) filter and super-absorbent-polymer (SAP) as an absorbent of tube type tear test kits. Methods: Tube type tear test kits (kit-CEL and kit-SAP) were made by inserting cellulose filter and super absorbent polymer respectively. To evaluate the repeatability of tear test kits made, the tip of the test kits were immersed for 1 to 5 seconds into solutions of 0.1, 0.5, 1.0, 1.5 and $2.0{\mu}{\ell}$. The experiment was repeated for 10 times, respectively. Correlation analysis and multiple regression analysis were performed for the effect of the amount of solution and absorption time on absorbed distance of the tear test kits. Results: The absorbed distances of the kit-CEL and kit-SAP were significantly increased with the volume of solution and absorption time, however kit-CEL showed lineality within $2{\mu}l$ and kit-SAP showed lineality within $1.5{\mu}l$ of solution. The absorption lengths of the kit-CEL and kit-SAP were correlated with the volume of solution and absorption time that correlation coefficients (r) were 0.683 and 0.705 with the volume of solution and 0.665 and 0.530 with the absorption time. The power of explanation ($R^2$) of the kit-CEL and kit-SAP were 0.840, 0.776 for the volume of solution and absorption time. The reliability of the kit-CEL and kit-SAP were measured as 0.998 and 0.987 respectively. Conclusion: The kit-CEL and kit-SAP showed good accuracy and high power of explanation for the volume of solution and absorption time that both kits could be evaluated as suitable tools for tear volume test, however, the kit-CEL could be more useful than kit-SAP.

목적: 흡수성이 좋은 셀룰로오스(cellulose, CEL) 필터와 고흡수성 폴리머(super absorbent polymer, SAP)를 삽입하여 제조한 튜브형 눈물검사키트의 유용성을 평가하고자 하였다. 방법: 흡수성이 좋은 재질 중 셀룰로오스 필터와 고흡수성 폴리머를 튜브에 삽입하여 튜브형 눈물검사키트(CEL-키트 와 SAP-키트)를 제작하고 제작한 눈물검사키트의 재현성을 평가하기 위하여 $0.1-2.0{\mu}{\ell}$의 용액의 양과 1-5초 검사시간에 따라 10회 반복 측정하여 평균값을 사용하여 평가하였다. 검사키트의 유용성을 평가하기 위하여 용액의 양과 흡수 시간에 따른 눈물검사키트 흡수 길이의 상관성을 분석하고, 다중회귀분석을 이용하여 용액의 양과 흡수 시간이 흡수 길이에 미치는 영향력을 분석하였다. 결과: CEL-키트와 SAP-키트 모두 용액의 양과 흡수 시간이 증가함에 따라 흡수된 길이가 유의하게 증가하였지만, CEL-키트는 $2.0{\mu}{\ell}$ 이내에서 상관성이 좋았고, SAP-키트는 $1.5{\mu}{\ell}$ 이내에서만 상관성을 보였다. CEL-키트와 SAP-키트의 흡수된 길이와 용액의 양에 대한 상관계수는 각각 r=0.683, r=0.705, 흡수시간에 대한 상관계수는 r=0.665, r=0.530로 나타났다. CEL-키트와 SAP-키트는 용액의 양과 흡수 시간에 대하여 0.840, 0.776의 설명력($R^2$)을 나타내었다. CEL-키트와 SAP-키트의 신뢰도는 각각 0.998, 0.987로 측정되었다. 결론: 개발한 CEL-키트와 SAP-키트는 용액의 양과 흡수 시간에 따라 정확도가 높고 용액의 양과 흡수시간에 대해서도 높은 설명력을 보여 눈물 양 검사에 좋은 방법으로 생각되며, CEL-키트가 더 유용한 검사키트로 생각된다.

Keywords

Acknowledgement

Supported by : Eulji University

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