Annals of Surgical Treatment and Research

The Korean Surgical Society (대한외과학회)
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Differences in the survival rates of older patients with colorectal cancers in 2003 and 2009

  • Shin, Je-Wook (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Park, Byung Kwan (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Kim, Min Jung (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Kim, Bun (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Kim, Byung Chang (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Park, Sung Chan (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Han, Kyung Su (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Sohn, Dae Kyung (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center) ;
  • Oh, Jae Hwan (Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center)
  • Received : 2016.07.19
  • Accepted : 2016.10.31
  • Published : 2017.04.01
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Abstract

Purpose: The aim of this study was to investigate survival in patients aged ${\geq}70years$ who underwent colorectal cancer surgery in 2003 and 2009. In addition, we aimed to identify the factors that could affect survival in these patients. Methods: In a cross-sectional study, a retrospective review of the data for 878 patients who underwent colorectal cancer surgery with curative intent in the years 2003 and 2009 was performed. The primary outcome was the 5-year overall survival rate (5-OSR), and the clinicopathologic factors that could affect overall survival were analyzed. Results: The 5-OSR was 77.8% and 84.9% in 2003 and 2009, respectively (P = 0.013). Age, American Society of Anesthesiologists physical status classification, stage, type of surgery, and length of hospital stay possibly affected survival per the univariate and multivariate analyses. In patients aged ${\geq}70years$, the 5-OSR in 2009 was 75.9%, which showed improvement compared to 53.7% in 2003 (P = 0.027). The stage, type of surgery, and hospital stay were the variables that possibly affected survival in patients aged ${\geq}70years$ per the univariate analysis, whereas the stage (III; hazard ratio [HR], 2.188; P = 0.005) and length of hospital stay (>12 days; HR, 2.307; P = 0.004), were the variables that showed statistical significance on the multivariate analysis. Conclusion: We found that early stage and shortening the length of hospital stay could affect survival in older patients with colorectal cancers. Because of limited evidence on the influence of shortening the length of hospital stay on survival in older patients, further investigations are warranted.

Keywords

Acknowledgement

Supported by : National Cancer Center

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