Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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High-Pitch Coronary CT Angiography at 70 kVp Adopting a Protocol of Low Injection Speed and Low Volume of Contrast Medium

  • Feng, Ruiqi (Department of Radiology, The First Affiliated Hospital of China Medical University) ;
  • Tong, Jiajie (Department of Radiology, Hebei General Hospital) ;
  • Liu, Xiaofei (Department of Radiology, The First Affiliated Hospital of China Medical University) ;
  • Zhao, Yu (Department of Radiology, The First Affiliated Hospital of China Medical University) ;
  • Zhang, Liang (Department of Radiology, The First Affiliated Hospital of China Medical University)
  • Received : 2016.09.18
  • Accepted : 2017.02.22
  • Published : 2017.10.01
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Abstract

Objective: To evaluate the feasibility and image quality (IQ) of prospectively high-pitch coronary CT angiography (CCTA) with low contrast medium injection rate at 70 kVp. Materials and Methods: One hundred and four patients with suspected coronary artery disease (body mass index < $26kg/m^2$, sinus rhythm and heart rate < 70 beats/min) were prospectively enrolled and randomly divided into two groups. In group A and group B, 28 mL and 40 mL of 370 mgI/mL iodinated contrast media was administrated at a flow rate of 3.5 and 5 mL/s, respectively. CT values, noise, signal-to-noise ratio, contrast-to-noise ratio (CNR) of the proximal segments of coronary arteries and subjective IQ were evaluated. Results: The CT values and noise in group A were significantly lower than those in group B (434-485 Hounsfield units [HU] vs. 772-851 HU, all p < 0.001; 17.8-22.3 vs. 23.3-26.4, all p < 0.005). The CNRs of the right coronary artery and left main artery showed no statistical difference between the two groups ($42.1{\pm}13.8$ vs. $36.8{\pm}16.0$, p = 0.074; $38.7{\pm}10.6$ vs. $38.1{\pm}17.0$, p = 0.819). No statistical difference was observed between the two groups in IQ scores ($3.04{\pm}0.75$ vs. $3.0{\pm}0.79$, p = 0.526) and diagnostic ratio (96.1% [50/52] vs. 94.2% [49/52], p = 0.647). Conclusion: Prospective high-pitch CCTA at 70 kVp with 28 mL of contrast media and injection rate of 3.5 mL/s could provide diagnostic IQ for normal-weight patients with heart rate of < 70 beats/min.

Keywords

References

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