Korean Journal of Radiology

  • 제18권4호
  • /
  • Pages.664-673
  • /
  • 2017
  • /
  • 1229-6929(pISSN)
  • /
  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지
DOI QR코드

DOI QR Code

Left Ventricular Functional Parameters and Geometric Patterns in Korean Adults on Coronary CT Angiography with a 320-Detector-Row CT Scanner

  • Kang, Eun-Ju (Department of Radiology, College of Medicine, Dong-A University) ;
  • Lee, Ki-Nam (Department of Radiology, College of Medicine, Dong-A University) ;
  • Choi, Won Jin (Department of Radiology, College of Medicine, Dong-A University) ;
  • Kim, Young-Dae (Department of Cardiology, College of Medicine, Dong-A University) ;
  • Shin, Kyung Min (Department of Radiology, Kyungpook National University) ;
  • Lim, Jae-Kwang (Department of Radiology, Kyungpook National University) ;
  • Lee, Jongmin (Department of Radiology, Kyungpook National University)
  • 투고 : 2016.09.14
  • 심사 : 2017.01.29
  • 발행 : 2017.08.01
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: To assess the normal reference values of left ventricle (LV) functional parameters in Korean adults on coronary CT angiography (CCTA) with a 320-detector-row CT scanner, and to analyze sex-related differences and correlations with various clinical characteristics. Materials and Methods: This study retrospectively enrolled 172 subjects (107 men and 65 women; age, $58{\pm}10.9years$; body surface area [BSA], $1.75{\pm}0.2m^2$) who underwent CCTA without any prior history of cardiac disease. The following parameters were measured by post-processing the CT data: LV volume, LV functional parameters (ejection fraction, stroke volume, cardiac output, etc.), LV myocardial mass, LV inner diameter, and LV myocardial thickness (including septal wall thickness [SWT], posterior wall thickness [PWT], and relative wall thickness [$RWT=2{\times}PWT/LV$ inner diameter]). All of the functional or volumetric parameters were normalized using the BSA. The general characteristics and co-morbidities for the enrolled subjects were recorded, and the correlations between these factors and the LV parameters were then evaluated. Results: The LV myocardial thickness (SWT, $1.08{\pm}0.18cm$ vs. $0.90{\pm}0.17cm$, p < 0.001; PWT, $0.91{\pm}0.15cm$ vs. $0.78{\pm}0.10cm$, p < 0.001; RWT, $0.38{\pm}0.08cm$ vs. $0.33{\pm}0.05cm$, p < 0.001), LV volume (LV end-diastolic volume, $112.9{\pm}26.1mL$ vs. $98.2{\pm}21.0mL$, p < 0.001; LV end-systolic volume, $41.7{\pm}14.7mL$ vs. $33.7{\pm}12.2mL$, p = 0.001) and mass ($145.0{\pm}29.1$ g vs. $107.9{\pm}20.0g$, p < 0.001) were significantly greater in men than in women. However, these differences were not significant after normalization using BSA, except for the LV mass (LV mass index, $79.6{\pm}14.0g/m^2$ vs. $66.2{\pm}11.0g/m^2$, p < 0.001). The cardiac output and ejection fraction were not significantly different between the men and women (cardiac output, $4.3{\pm}1.0L/min$ vs. $4.2{\pm}0.9L/min$, p = 0.452; ejection fraction, $63.4{\pm}7.7%$ vs. $66.4{\pm}7.6%$, p = 0.079). Most of the LV parameters were positively correlated with BSA, body weight, and total Agatston score. Conclusion: This study provides sex-related reference values and percentiles for LV on cardiac CT and should assist in interpreting results.

키워드

과제정보

연구 과제 주관 기관 : National Research Foundation of Korea (NRF), Guerbet

참고문헌

  1. Raff GL, Gallagher MJ, O'Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol 2005;46:552-557 https://doi.org/10.1016/j.jacc.2005.05.056
  2. Kim YJ, Yong HS, Kim SM, Kim JA, Yang DH, Hong YJ, et al. Korean guidelines for the appropriate use of cardiac CT. Korean J Radiol 2015;16:251-285 https://doi.org/10.3348/kjr.2015.16.2.251
  3. Lin FY, Min JK. Assessment of cardiac volumes by multidetector computed tomography. J Cardiovasc Comput Tomogr 2008;2:256-262 https://doi.org/10.1016/j.jcct.2008.05.144
  4. Mahnken AH, Bruners P, Schmidt B, Bornikoel C, Flohr T, Gunther RW. Left ventricular function can reliably be assessed from dual-source CT using ECG-gated tube current modulation. Invest Radiol 2009;44:384-389 https://doi.org/10.1097/RLI.0b013e3181a4d874
  5. Juergens KU, Grude M, Maintz D, Fallenberg EM, Wichter T, Heindel W, et al. Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience. Radiology 2004;230:403-410 https://doi.org/10.1148/radiol.2302030042
  6. Raman SV, Shah M, McCarthy B, Garcia A, Ferketich AK. Multi-detector row cardiac computed tomography accurately quantifies right and left ventricular size and function compared with cardiac magnetic resonance. Am Heart J 2006;151:736-744 https://doi.org/10.1016/j.ahj.2005.04.029
  7. Asferg C, Usinger L, Kristensen TS, Abdulla J. Accuracy of multi-slice computed tomography for measurement of left ventricular ejection fraction compared with cardiac magnetic resonance imaging and two-dimensional transthoracic echocardiography: a systematic review and meta-analysis. Eur J Radiol 2012;81:e757-e762 https://doi.org/10.1016/j.ejrad.2011.01.009
  8. Stolzmann P, Scheffel H, Leschka S, Schertler T, Frauenfelder T, Kaufmann PA, et al. Reference values for quantitative left ventricular and left atrial measurements in cardiac computed tomography. Eur Radiol 2008;18:1625-1634 https://doi.org/10.1007/s00330-008-0939-4
  9. Lin FY, Devereux RB, Roman MJ, Meng J, Jow VM, Jacobs A, et al. Cardiac chamber volumes, function, and mass as determined by 64-multidetector row computed tomography: mean values among healthy adults free of hypertension and obesity. JACC Cardiovasc Imaging 2008;1:782-786 https://doi.org/10.1016/j.jcmg.2008.04.015
  10. Gardin JM, Wagenknecht LE, Anton-Culver H, Flack J, Gidding S, Kurosaki T, et al. Relationship of cardiovascular risk factors to echocardiographic left ventricular mass in healthy young black and white adult men and women. The CARDIA study. Coronary Artery Risk Development in Young Adults. Circulation 1995;92:380-387 https://doi.org/10.1161/01.CIR.92.3.380
  11. Natori S, Lai S, Finn JP, Gomes AS, Hundley WG, Jerosch-Herold M, et al. Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol 2006;186(6 Suppl 2):S357-S365 https://doi.org/10.2214/AJR.04.1868
  12. Chen JJ, Manning MA, Frazier AA, Jeudy J, White CS. CT angiography of the cardiac valves: normal, diseased, and postoperative appearances. Radiographics 2009;29:1393-1412 https://doi.org/10.1148/rg.295095002
  13. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification. Eur J Echocardiogr 2006;7:79-108 https://doi.org/10.1016/j.euje.2005.12.014
  14. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2015;16:233-270 https://doi.org/10.1093/ehjci/jev014
  15. Christner JA, Kofler JM, McCollough CH. Estimating effective dose for CT using dose-length product compared with using organ doses: consequences of adopting International Commission on Radiological Protection publication 103 or dual-energy scanning. AJR Am J Roentgenol 2010;194:881-889 https://doi.org/10.2214/AJR.09.3462
  16. Evans JD. Straightforward statistics for the behavioral sciences. Pacific Grove: Brooks/Cole Publishing, 1996
  17. Nham E, Kim SM, Lee SC, Chang SA, Sung J, Cho SJ, et al. Association of cardiovascular disease risk factors with left ventricular mass, biventricular function, and the presence of silent myocardial infarction on cardiac MRI in an asymptomatic population. Int J Cardiovasc Imaging 2016;32 Suppl 1:173-181
  18. Bernard Y, Meneveau N, Boucher S, Magnin D, Anguenot T, Schiele F, et al. Lack of agreement between left ventricular volumes and ejection fraction determined by two-dimensional echocardiography and contrast cineangiography in postinfarction patients. Echocardiography 2001;18:113-122 https://doi.org/10.1046/j.1540-8175.2001.00113.x
  19. Picard MH, Popp RL, Weyman AE. Assessment of left ventricular function by echocardiography: a technique in evolution. J Am Soc Echocardiogr 2008;21:14-21 https://doi.org/10.1016/j.echo.2007.11.007
  20. Chang SA, Choe YH, Jang SY, Kim SM, Lee SC, Oh JK. Assessment of left and right ventricular parameters in healthy Korean volunteers using cardiac magnetic resonance imaging: change in ventricular volume and function based on age, gender and body surface area. Int J Cardiovasc Imaging 2012;28 Suppl 2:141-147 https://doi.org/10.1007/s10554-012-0150-1
  21. Sandstede J, Lipke C, Beer M, Hofmann S, Pabst T, Kenn W, et al. Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol 2000;10:438-442 https://doi.org/10.1007/s003300050072
  22. Tong W, Lima JA, Lai H, Celentano DD, Dai S, Lai S. Relation of coronary artery calcium to left ventricular mass in African-Americans. Am J Cardiol 2004;93:490-492 https://doi.org/10.1016/j.amjcard.2003.10.053
  23. Mo YH, Jaw FS, Wang YC, Jeng CM, Peng SF. Effects of propranolol on the left ventricular volume of normal subjects during CT coronary angiography. Korean J Radiol 2011;12:319-326 https://doi.org/10.3348/kjr.2011.12.3.319

피인용 문헌

  1. Age of Data in Contemporary Research Articles Published in Representative General Radiology Journals vol.19, pp.6, 2018, https://doi.org/10.3348/kjr.2018.19.6.1172
  2. Congenital absence of the right coronary artery : A case report and literature review vol.97, pp.12, 2017, https://doi.org/10.1097/md.0000000000010187
  3. Clinical Applications of Wide-Detector CT Scanners for Cardiothoracic Imaging: An Update vol.20, pp.12, 2019, https://doi.org/10.3348/kjr.2019.0327
  4. Assessment of Left Ventricular Myocardial Diseases with Cardiac Computed Tomography vol.20, pp.3, 2017, https://doi.org/10.3348/kjr.2018.0280
  5. Role of Cardiac Computed Tomography in the Diagnosis of Left Ventricular Myocardial Diseases vol.27, pp.2, 2017, https://doi.org/10.4250/jcvi.2019.27.e17
  6. Percutaneous coronary intervention for congenital absence of the right coronary artery with acute myocardial infarction : A case report and literature review vol.99, pp.5, 2020, https://doi.org/10.1097/md.0000000000018981
  7. Effects of epicardial adipose tissue volume and density on cardiac structure and function in patients free of coronary artery disease vol.38, pp.7, 2020, https://doi.org/10.1007/s11604-020-00951-3
  8. Congenital absence of the right coronary artery with acute myocardial infarction: report of two cases and review of the literature vol.48, pp.12, 2017, https://doi.org/10.1177/0300060520971508
  9. Posterior myocardial infarction caused by superdominant circumflex occlusion over an absent right coronary artery : Case report and review of literature vol.100, pp.27, 2017, https://doi.org/10.1097/md.0000000000026604