Korean Journal of Radiology

  • 제18권3호
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  • Pages.487-497
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  • 2017
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지
DOI QR코드

DOI QR Code

Characteristics Detected on Computed Tomography Angiography Predict Coronary Artery Plaque Progression in Non-Culprit Lesions

  • Tan, Yahang (Department of Cardiology, Chinese PLA General Hospital) ;
  • Zhou, Jia (Department of Cardiology, Chinese PLA General Hospital) ;
  • Zhou, Ying (Department of Cardiology, Chinese PLA General Hospital) ;
  • Yang, Xiaobo (Department of Cardiology, Chinese PLA General Hospital) ;
  • Yang, Junjie (Department of Cardiology, Chinese PLA General Hospital) ;
  • Chen, Yundai (Department of Cardiology, Chinese PLA General Hospital)
  • 투고 : 2016.06.25
  • 심사 : 2016.10.03
  • 발행 : 2017.06.01
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: This study sought to determine whether variables detected on coronary computed tomography angiography (CCTA) would predict plaque progression in non-culprit lesions (NCL). Materials and Methods: In this single-center trial, we analyzed 103 consecutive patients who were undergoing CCTA and percutaneous coronary intervention (PCI) for culprit lesions. Follow-up CCTA was scheduled 12 months after the PCI, and all patients were followed for 3 years after their second CCTA examination. High-risk plaque features and epicardial adipose tissue (EAT) volume were assessed by CCTA. Each NCL stenosis grade was compared visually between two CCTA scans to detect plaque progression, and patients were stratified into two groups based on this. Logistic regression analysis was used to evaluate the factors that were independently associated with plaque progression in NCLs. Time-to-event curves were compared using the log-rank statistic. Results: Overall, 34 of 103 patients exhibited NCL plaque progression (33%). Logistic regression analyses showed that the NCL progression was associated with a history of ST-elevated myocardial infarction (odds ratio [OR] = 5.855, 95% confidence interval [CI] = 1.391-24.635, p = 0.016), follow-up low-density lipoprotein cholesterol level (OR = 6.832, 95% CI = 2.103-22.200, p = 0.001), baseline low-attenuation plaque (OR = 7.311, 95% CI = 1.242-43.028, p = 0.028) and EAT (OR = 1.015, 95% CI = 1.000-1.029, p = 0.044). Following the second CCTA examination, major adverse cardiac events (MACEs) were observed in 12 patients, and NCL plaque progression was significantly associated with future MACEs (log rank p = 0.006). Conclusion: Noninvasive assessment of NCLs by CCTA has potential prognostic value.

키워드

참고문헌

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피인용 문헌

  1. Age of Data in Contemporary Research Articles Published in Representative General Radiology Journals vol.19, pp.6, 2018, https://doi.org/10.3348/kjr.2018.19.6.1172
  2. Plaque Assessment on Serial Coronary CTA vol.12, pp.3, 2019, https://doi.org/10.1007/s12410-019-9483-7