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Prevalence of and Risk factors for Latent Tuberculosis Infection among Employees at a Workers' Compensation Hospital

산재요양기관 종사자에서 잠복결핵감염 유병율 및 위험요인

  • Hwang, Joohwan (Occupational Lung Diseases Institute, Korea Workers' Compensation and Welfare Service) ;
  • Jeong, JiYoung (Occupational Lung Diseases Institute, Korea Workers' Compensation and Welfare Service) ;
  • Choi, Byung-soon (Occupational Lung Diseases Institute, Korea Workers' Compensation and Welfare Service)
  • 황주환 (근로복지공단 직업성폐질환연구소) ;
  • 정지영 (근로복지공단 직업성폐질환연구소) ;
  • 최병순 (근로복지공단 직업성폐질환연구소)
  • Received : 2017.08.17
  • Accepted : 2017.09.25
  • Published : 2017.09.30

Abstract

Objectives: The major objective of this study was to investigate the prevalence of and risk factors for latent tuberculosis infection (LTBI) among employees at a workers' compensation hospital. Methods: Among the 394 employees at Incheon Hospital, 362 were enrolled in the study. An interferon-gamma release assay(IGRA) for diagnosis of LTBI was performed using QuantiFERON$^{(R)}$ TB Gold In-Tube(QFT-IT). Risk factors for LTBI were analyzed using logistic regression analysis. Results: The overall prevalence of LTBI was 32.0%(116/362). The non-medical departments have a significantly high prevalence compared to medical departments(39.7% vs 23.2%). In multivariate logistic regression analysis, experience working in the pneumoconiosis hospital(OR, 3.6; 95% CI, 1.3-10.3) was associated with development of LTBI. Conclusions: Korean guidelines for the management of tuberculosis recommend annual regular health examinations for TB and LTBI for health care workers(HCWs). Considering the high prevalence of and risk factors for LTBI among non-HCWs, it suggests a need for annual regular health examinations for TB and LTBI for all employees at workers' compensation hospitals, including pneumoconiosis hospitals.

Keywords

References

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