Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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In vitro antioxidant property and α-glucosidase and pancreatic lipase inhibiting activities of Jeju camellia mistletoe (Korthalsella japonica (Thunb.) Engl.) extracts

제주 동백나무 겨우살이(Korthalsella japonica (Thunb.) Engl.)의 항산화 및 α-glucosidase와 pancreatic lipase 저해 활성

  • Park, Eun Mi (Toxicology Laboratory, Major in Biomaterials, SARI, Jeju National University) ;
  • Kim, Min Young (Toxicology Laboratory, Major in Biomaterials, SARI, Jeju National University)
  • Received : 2017.06.11
  • Accepted : 2017.08.08
  • Published : 2017.09.29
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Abstract

The antioxidant activity of various solvent extracts from Jeju camellia mistletoe (Korthalsella japonica (Thunb.) Engl.) was investigated using various in vitro assays as the 1,1-diphenyl-2-picrylhydrazyl radical scavenging, ferrous ion chelating and reducing power assays. Methanol and ethanol extracts showed the most potent antioxidant activity in all assays tested followed by water extract. The inhibitory effect of the Jeju camellia mistletoe extracts on pancreatic lipase and $\acute{a}$-glucosidase was also evaluated and the results showed that methanol and ethanol extracts markedly reduced both enzyme activities. Therefore, the methanol and ethanol extracts of Jeju camellia mistletoe is definitely worthy of further investigation for these beneficial effects on nutraceutical medicine.

제주 동백나무 겨우살이 추출물의 항산화 활성을 DPPH 라디컬 소거능, 철이온 킬레이팅과 환원력 시험을 통해 조사한 결과, 메탄올과 에탄올 추출물이 열수 추출물보다 뛰어난 항산화 효능을 보였다. ${\alpha}$-Glucosidase와 pancreatic lipase 저해능 또한 메탄올과 에탄올 추출물이 우수한 활성을 보였다. 따라서, 제주 동백 나무 겨우살이의 메탄올 및 에탄올 추출물을 건강기능 의약식품 소재로 개발하기 위한 추가 연구가 진행되어야 할 것이다.

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