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Design of a Pattern Classifier for Pain Awareness using Electrocardiogram

심전도를 이용한 통증자각 패턴분류기 설계

  • Lim, Hyunjun (Dept. of Medical Engineering, Yonsei University College of Medicine) ;
  • Yoo, Sun Kook (Dept. of Medical Engineering, Yonsei University College of Medicine)
  • Received : 2017.05.31
  • Accepted : 2017.08.22
  • Published : 2017.09.30

Abstract

Although several methods have been used to assess the pain levels, few practical methods for classifying presence or absence of the pain using pattern classifiers have been suggested. The aim of this study is to design an pattern classifier that classifies the presence or absence of the pain using electrocardiogram (ECG). We measured the ECG signal from 10 subjects with the painless state and the pain state(Induced by mechanical stimulation). The 10 features of heart rate variability (HRV) were extracted from ECG - MeanRRI, SDNN, rMSSD, NN50, pNN50 in the time domain; VLF, LF, HF, Total Power, LF/HF in the frequency domain; and we used the features as input vector of the pattern classifier's artificial neural network (ANN) / support vector machine (SVM) for classifying the presence or absence of the pain. The study results showed that the classifiers using ANN / SVM could classify the presence or absence of the pain with accuracies of 81.58% / 81.84%. The proposed classifiers can be applied to the objective assessment of pain level.

Keywords

References

  1. Raj, P. Prithvi., Taxonomy and Classification of Pain, The Handbook of Chronic Pain, Nova Science Publishers, New York, pp. 41-56, 2007.
  2. C.R. Chapman, R.P. Tuckett, and C.W. Song, "Pain and Stress in a Systems Perspective: Reciprocal Neural, Endocrine, and Immune Interactions," The Journal of Pain, Vol. 9, No. 2, pp. 122-145, 2008. https://doi.org/10.1016/j.jpain.2007.09.006
  3. H. Breivik, P.C. Borchgrevink, S.M. Allen, L.A. Rosseland, L. Romundstad, and E.K. Breivik Hals, et al., "Assessment of Pain," British Journal of Anaesthesia, Vol. 101, No. 1, pp. 17-24, 2008. https://doi.org/10.1093/bja/aen103
  4. C.T. Hartrick, J.P. Kovan, and S. Shapiro, "The Numeric Rating Scale for Clinical Pain Measurement: A Ratio Measure?," Pain Practice, Vol. 3, No. 4, pp. 310-316, 2003. https://doi.org/10.1111/j.1530-7085.2003.03034.x
  5. A. Williamson and B. Hoggart, "Pain: A Review of Three Commonly Used Pain Rating Scales," Journal of Clinical Nursing, Vol. 14, No. 7, pp. 798-804, 2005. https://doi.org/10.1111/j.1365-2702.2005.01121.x
  6. K. Hornik, M. Stinchcombe, and H. White, "Multilayer Feedforward Networks are Universal Approximators," Neural Networks, Vol. 2, No. 5, pp. 359-366, 1989. https://doi.org/10.1016/0893-6080(89)90020-8
  7. C. Cortes and V. Vapnik, "Support-vector Network," Machine Learning, Vol. 20, pp. 273-297, 1995.
  8. I. El-Naqa, Y. Yang, M.N. Wernick, N.P. Galatsanos, and R.M. Nishikawa, "A Support Vector Machine Approach for Detection of Microcalcifications," IEEE Transactions on Medical Imaging, Vol. 21, No. 12, pp. 1552-1563, 2002. https://doi.org/10.1109/TMI.2002.806569
  9. C.J.C. Burges, "A Tutorial on Support Vector Machines for Pattern Recognition," Data Mining and Knowledge Discovery, Vol. 2, No. 2, pp. 121-167, 1998. https://doi.org/10.1023/A:1009715923555
  10. M.H. Hyun and C.S. Kim, “Experimental Pain Induction and Subjective Pain Assessments,” Korean Journal of Stress Research, Vol. 10, No. 2, pp. 51-58, 2002.
  11. J.H. Kim, S.M. Lee and K.H. Park, "P-Waves and T-Wave Detection Algorithm in the ECG Signals Using Step-by-Step Baseline Alignment," Journal of Korea Multimedia Society, Vol. 19, No. 6, pp. 1034-1042, 2016. https://doi.org/10.9717/kmms.2016.19.6.1034
  12. J. Pan and W.J. Tompkins, "A Real-Time QRS Detection Algorithm," IEEE Transactions on Biomedical Engineering, Vol. 3, pp. 230-236, 1985.
  13. G.G. Berntson, J.T. Bigger, D.L. Eckberg, P. Grossman, P.G. Kaufmann, M. Malik, et al., "Heart Rate Variability: Origins, Methods, and Interpretive Caveats," Psychophysiology, Vol. 34, No. 6, pp. 623-648, 1997. https://doi.org/10.1111/j.1469-8986.1997.tb02140.x
  14. A.J. Camm, M. Malik, J.T. Bigger, G. Breithardt, S. Cerutti, R.J. Cohen, et al., "Heart Rate Variability: Standards of Measurement, Physiological Interpretation and Clinical Use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology," Circulation, Vol. 93, pp. 1043-1065, 1996. https://doi.org/10.1161/01.CIR.93.5.1043
  15. F. Keinosuke, Introduction to Statistical Pattern Recognition, Academic Press, San Diego. 2013.
  16. R.C. Gonzalez, R.E. Woods, and S.L. Eddins, Digital Image Processing Using MATLAB, McGraw Hill , New York. 2011.