Pediatric Gastroenterology, Hepatology & Nutrition

The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition (대한소아소화기영양학회)
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Eosinophilic Gastrointestinal Disorder Presenting as Intractable Vomiting and Ascites in a Young Girl

  • Kwon, Ji Yoon (Department of Pediatrics, Korea University College of Medicine) ;
  • Huh, Ji Sun (Department of Pediatrics, Korea University College of Medicine) ;
  • Je, Bo Kyung (Department of Radiology, Korea University College of Medicine) ;
  • Hong, Kwang Dae (Department of Colorectal Surgery, Korea University College of Medicine) ;
  • Lee, Jee Hyun (Department of Pediatrics, Korea University College of Medicine)
  • Received : 2016.07.26
  • Accepted : 2016.09.05
  • Published : 2017.09.30
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Abstract

Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after influenza virus infection. Peripheral eosinophilia was not present. The diagnosis was confirmed by biopsy of the bowel wall through laparotomy and endoscopy, and controlled by 2 courses of steroid therapy due to recurring symptoms. Influenza virus infection was assumed to play a role in the onset of EGID through a Th2 response that stimulated eosinophilic infiltration in the GI tract. We therefore report this case along with a literature review.

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References

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