한국방사선학회논문지 (Journal of the Korean Society of Radiology)

  • 제11권4호
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  • Pages.227-234
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  • 2017
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  • 1976-0620(pISSN)
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  • 2384-0633(eISSN)
한국방사선학회 (The Korean Society of Radiology)
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탄성초음파에서 갑상샘 결절의 감별진단을 위한 탄성도 점수와 변형비의 유용성 평가

Evaluation of the Usefulness of Differential Diagnosis of Thyroid Nodules using Elasticity Score and Strain Ratio in Elastogpraphy

  • 이진수 (인제대학교 해운대백병원 영상의학과) ;
  • 양성희 (일신기독병원 영상의학과) ;
  • 김창수 (부산가톨릭대학교 방사선학과) ;
  • 안현 (인제대학교 부산백병원 영상의학과)
  • Lee, Jin-Soo (Department of Radiology, Inje University Haeundae Paik Hospital) ;
  • Yang, Sung-Hee (Department of Radiology, Ilsin Christian Hospital) ;
  • Kim, changsoo (Department of Radiological Science, Pusan Catholic University) ;
  • An, Hyun (Department of Radiology, Inje University Busan Paik Hospital)
  • 투고 : 2017.06.30
  • 심사 : 2017.08.31
  • 발행 : 2017.08.31
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초록

본 연구는 갑상샘 탄성초음파에서 탄성도 점수와 변형비를 이용한 방법이 양성과 악성결절의 감별진단에 유용한지를 평가하였다. 탄성초음파를 시행한 597명을 대상으로 하였으며, 세침흡인세포검사 결과를 바탕으로 후향적인 분석을 하였다. 갑상샘 결절의 양성과 악성에 따른 5단계의 탄성도 점수와 변형비의 차이분석은 카이제곱검정과 Mann-Whitney U test를 실시하였다. ROC 곡선분석을 통해 악성결절의 예측을 위한 탄성도 점수와 변형비의 최적의 cut off 값을 결정하였다. 양성과 악성결절 군의 분류에 따른 탄성도 점수의 동질성 비교와 변형비의 차이검증 결과에서 각각 통계적으로 유의한 차이를 보였으며(p=0.000), ROC 곡선분석에서 양성과 악성결절의 예측을 위한 탄성도 점수와 변형비의 AUC 0.842, 0.700, cut-off 값 3, 2.49로 결정되었다(p=0.001). 따라서 탄성도 점수와 변형비는 갑상샘 결절의 감별진단에 도움을 줄 수 있을 것이다.

This study evaluated the usefulness of the elasticity score and strain ratio in the differential diagnosis of benign and malignant nodules in thyroid elastography. We performed a retrospective analysis based on the results of fine needle aspiration cytology. The Chi-square test and the Mann-Whitney U test were used to analyze the difference between the five degrees of elasticity score and strain ratio according to the benign and malignant thyroid nodules. ROC curve analysis was used to determine the elasticity score and the best cut-off value of the strain ratio for the prediction of malignant nodules. There was a statistically significant difference (p=0.000) between the homogeneity of the elasticity score and the difference of the strain ratio between the benign and malignant nodule groups. On the ROC curve analysis, the elasticity score and the srain ratio for predicting benign and malignant nodules were determined as AUC 0.842, 0.700, cut-off value 3, 2.49 (p=0.001). Therefore, the elasticity score and strain ratio may be useful in the differential diagnosis of thyroid nodules.

키워드

참고문헌

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