DOI QR코드

DOI QR Code

Association between Socioeconomic Status and Hepatitis C Prevalence among Community-Dwelling Adults

전라남도 일지역 거주 성인의 사회경제적 지위와 C형 간염과의 관계

  • Received : 2017.03.16
  • Accepted : 2017.05.01
  • Published : 2017.08.31

Abstract

Purpose: This study was conducted to evaluate the socioeconomic status as a risk factor for hepatitis C virus infection among community-dwelling adults in Korea. Methods: This study was a cross-sectional study including 2,617 adults. Data from hepatocellular carcinoma epidemiological investigation and information regarding three markers of socioeconomic status, education, employment, household income, were obtained. Multiple logistic regression was performed to calculate odds ratios (ORs) for hepatitis C virus infection for socioeconomic status markers, adjusting for the other soioeconomic status marker, behavioral and hepatitis-related factors. Results: Of the 2,617 study subjects, 104 subjects infected with hepatitis C virus and prevalence was 4%. When compared to subjects with a lowest education, ORs was 0.16 (95% confidence interval [CI]: 0.04-0.69) for highest education group. After adjusting behavioral and hepatitis-related factors, ORs was 0.20 (0.05-0.87) for highest education compared with lowest group. Conclusion: Low educational level was associated with an increased risk of hepatitis C virus infection.

Keywords

References

  1. Alter, M. J., Kruszon-Moran, D., Nainan, O. V., McQuillan, G. M., Gao, F., Moyer, L. A., et al. (1999). The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. The New England Journal of Medicine, 341(8), 556-562. https://doi.org/10.1056/NEJM199908193410802
  2. Armstrong, G. L., Wasley, A., Simard, E. P., McQuillan, G. M., Kuhnert, W. L., & Alter, M. J. (2006). The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Annals of Internal Medicine, 144(10), 705-714. https://doi.org/10.7326/0003-4819-144-10-200605160-00004
  3. Averhoff, F. M., Glass, N., & Holtzman, D. (2012). Global burden of hepatitis C: considerations for healthcare provider in the United States. Clinical Infectious Disease, 55(Suppl 1), S10-15. http://dx.doi.org/10.1093/cid/cis361
  4. Dalgard, O., Jeansson, S., Skaug, K., Raknerud, N., & Bell, H. (2003). Hepatitis C in the general adult population of Oslo; prevalence and clinical spectrum. Scandinavian Journal of Gastroenterology, 38(8), 864-870. https://doi.org/10.1080/00365520310004542
  5. Hastert, T. A., Beresford, S. A., Sheppard, L., & White, E. (2015). Disparities in cancer incidence and mortality by area-level socioeconomic status: a multilevel analysis. Journal of Epidemiology and Community Health, 69(2), 168-176. http://dx.doi.org/10.1136/jech-2014-204417
  6. Institute of Medicine. (2010). Hepatitis and liver cancer: a national strategy for prevention and control of hepatitis B and C, Washington, DC: The National Academies Press.
  7. Jeong, S. H. (2017). Current status of hepatitis C virus infection and countermeasures. Public Health Weekly Report, KCDC, 10(9), 212-219.
  8. Kim, C. Y., Lee, H. S., & Han, C. J. (1993). Relative Etiologic role of hepatitis B virus and hepatitis C virus in chronic liver diseases and hepatocellular carcinoma among age-specific groups in Korea: the possible presence of Non-B, Non-C agents. The Seoul Journal of Medicine, 34(1), 27-33.
  9. Kim, I. H., Jeong, S. H., Cho, Y. K., Lee, J. H., Jin, Y. J., Lee, D., et al. (2013). A nationwide seroepidemiology of hepatitis C virus infection in South Korea. Liver International, 33(4), 589-594. http://dx.doi.org/10.1111/liv.12108
  10. Korea Centers for Disease Control and Prevention. (2013). Survey on prevalence and risk factors in high risk area of hepatitis C(2013E2400100), Osong: Author.
  11. Kozakiewicz, K., Podolecka, E., Kwasniewska, M., Drygas, W., Pajak, A., & Tendera, M. (2016). Association between socioeconomic status and cardiovascular risk. Kardiologia Polska, 74(2), 179-184. http://dx.doi.org/10.5603/KP.a2015.0139
  12. Lavanchy, D. (2011). Evolving epidemiology of hepatitis C virus. Clinical Microbiology and Infection, 17(2), 107-115. http://dx.doi.org/10.1111/j.1469-0691.2010.03432.x
  13. Lee, K. I., Park, K. S., Seo, H. J., Kim, T. Y., Kim, E. S., Jang, B.K., et al. (2011). Shifting in seroprevalence of HBsAg and Anti-HCV during recent 10 years in adults resident in Daegu and Gyeongbuk province. The Korean Journal of Gastroenterology, 58(2), 82-87. https://doi.org/10.4166/kjg.2011.58.2.82
  14. Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., et al. (2012). Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010. Lancet, 380(9859), 2095-2128. http://dx.doi.org/10.1016/S0140-6736(12)61728-0
  15. Madhava, V., Burgess, C., & Drucker, E. (2002). Epidemiology of chronic hepaitis C virus infection in sub-Saharan Africa. The Lancet. Infectious Disease, 2(5), 293-302.
  16. Meffre, C., Le Strat, Y., Delarocque-Astagneau, E., Dubois, F., Antona, D., Lemasson, J. M., et al. (2010). Prevalence of hepatitis B and hepatitis C virus infections in France in 2004: social factors are important predictors after adjusting for known risk factors. Journal of Medical Virology, 82(4), 546-555. http://dx.doi.org/10.1002/jmv.21734
  17. Mohd Hanafiah, K., Groeger, J., Flaxman, A. D., & Wiersma, S. T. (2013). Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology, 57(4), 1333-1342. http://dx.doi.org/10.1002/hep.26141
  18. Omland, L. H., Osler, M., Jepsen, P., Krarup, H., Weis, N., Christensen, P. B., et al. (2013). Socioeconomic status in HCV infected patients-risk and prognosis. Clinical Epidemiology, 5, 163-172. http://dx.doi.org/10.214/CLEP.S43926
  19. Qureshi, H., Bile, K. M., Jooma, R., Alam, S. E., & Afridi, H. U. (2010). Prevalence of hepatitis B and C viral infections in Pakistan: findings of a national survey appealing for effective prevention and control measures. Eastern Mediterranean Health Journal, 16(Suppl), S15-23. https://doi.org/10.26719/2010.16.Supp.15
  20. Shepard, C. W., Finelli, L., & Alter, M. (2005). Global epidemiology of hepatitis C virus infection. The Lancet. Infectious Disease, 5(9), 558-567. http://dx.doi.org/10.1016/S1473-3099(05)70216-4
  21. Shin, A., Cho, E. R., Kim, J., Sung, J., Park, K. W., Lim, M. K., et al. (2009). Factors associated with awareness of infection status among chronic hepatitis B and C carriers in Korea. Cancer Epidemiology, Biomarkers & Prevention, 18(6), 1894-1898. http://dx.doi.org/10.1158/1055-9965
  22. Shin, H. R. (2006). Epidemiology of hepatitis C virus in Korea. Intervirology, 49(1-2), 18-22. http://dx.doi.org/10.1159/000087258
  23. Shin, H. R., Kim, J. Y., Song, J. B., Suh, B. S., Kim, J. M., Lee, B. O., et al. (1997). Seroepidemiologic study of hepatitis B virus(HBV) and hepatitis C(HCV) infection among Koreans in rural area, Korea. Journal of Preventive Medicine and Public Health, 30(1), 17-29.
  24. Stanaway, J. D., Flaxman, A. D., Naghavi, M., Fitzmaurice, C., Vos, T., Abubakar, I., et al. (2016). The global burden of viral hepatitis from 1990 to 2013; findings from the Gobal Burden of Disease Study 2013. Lancet, 388(10049), 1081-1088. http://dx.doi.org/10.1016/S0140-6736(16)30579-7
  25. Suh, D. H., & Jeong, S. H. (2006). Current status of hepatitis C virus infection in Korea. Intervirology, 49(1-2), 70-75. http://dx.doi. org/10.1159/000087266
  26. Torre, L. A., Bray, F., Siegel, R. L., Ferlay, J., Lortet-Tieulent, J., & Jemal, A. (2015). Global cancer statistics, 2012. A Cancer Journal for Clinicians, 65(2), 87-108. http://dx.doi.org/10.3322/caac.21262
  27. World Health Organization. (2004). Global burden of disease (GBD) for hepatitis C. Journal of Clinical Pharmacology, 44(1), 20-29. http://dx.doi.org/10.1177/0091270003258669
  28. World Health Organization. (2016). Media Centre: Fact sheets. Retrieved July 28, 2016, from http://www.who.int/mediacentre/factsheets/fs164/en/