The Journal of the Korea Contents Association (한국콘텐츠학회논문지)

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Effect of Gd-EOB-DTPA on Hepatic Fat Quantification using Two-point Dixon Technique

Two-point Dixon기법을 이용한 간의 지방정량화에 Gd-EOB-DTPA가 미치는 영향

  • 구노현 (서울아산병원 영상의학과) ;
  • 최관우 (서울아산병원 영상의학과) ;
  • 유병규 (원광보건대학교 방사선과)
  • Received : 2017.04.04
  • Accepted : 2017.05.04
  • Published : 2017.07.28
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Abstract

The purpose of present study was to assess whether Gd-EOB-DTPA with gadolinium-based contrast agent administration affects fat quantification using the two-point Dixon technique. Between April 2016 and September, 60 patients who underwent hepatic fat quantification using the two-point Dixon technique were divided into two group (normal liver donors=30, abnormal hepatic steatosis=30) and we compared the variability of mean fat fraction before and after administration Gd-EOB-DTPA. As a results, in both group, fat fraction after injection Gd-EOB-DTPA was significantly decreased (normal liver donors -33.8%, hepatic steatosis -47.2%) compared to before injection Gd-EOB-DTPA, suggesting that Gd-EOB-DTPA affects fat quatification using two-point Dixon technique. In conclusion, hepatic fat quantification using the two-point Dixon technique could maintain diagnostic value by acquiring images before administration Gd-EOB-DTPA.

본 연구는 two-point Dixon기법을 이용한 간의 지방정량화 검사 시 가돌리늄 조영제인 Gd-EOB-DTPA가 지방정량화에 어떠한 영향을 미치는지 알아보고자 하였다. 연구방법은 2016년 4월부터 동년 9월까지 two-point Dixon 기법을 이용해 간의 지방정량화 검사를 시행한 60명을, 두 그룹(정상의 간기증자 30명, 비정상의 간 지방증 환자 30명)으로 분류한 후 조영제 주입에 따른 지방분율의 변화를 비교 평가하였다. 연구 결과, 두 그룹 모두 조영제 주입 전 보다 후의 지방분율이 크게 감소(간 기증자 -33.8%, 간 지방증 환자 -47.2%)하는 것으로 나타나 Gd-EOB-DPTA가 지방정량화에 영향을 미친다는 것을 알 수 있었다. 결론적으로 two-point Dixon기법을 이용해 간 지방정량화 검사를 시행할 경우, Gd-EOB-DTPA 주입 전에 영상을 획득해야 지방분율의 변화를 최소화 할 수 있어 정확한 진단을 할 수 있다.

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References

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