Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지
DOI QR코드

DOI QR Code

Primary intestinal mast cell tumor in a Russian Blue cat: ultrasonographic and histopathological findings

  • Received : 2016.11.03
  • Accepted : 2017.04.04
  • Published : 2017.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

A 11-year-old, female Russian Blue cat was presented with anorexia, vomiting, and diarrhea lasting for 3 days. Abdominal ultrasonography revealed a hypoechoic, non-circumferential, and eccentrically formed intestinal loop with altered wall layering and thickening of the tunica muscularis. After surgical resection, histopathologic examination confirmed an infiltrative, round-cell neoplasm composed of sheets and cords of neoplastic mast cells within a fibrotic, edematous stroma. The cat was alive and healthy 6 months after surgery. To the best of our knowledge, this is the first reported case of an intestinal mast cell tumor in a Russian Blue cat in South Korea.

Keywords

References

  1. Batlle M, Perez-Villa F, Lazaro A, Garcia-Pras E, Ramirez J, Ortiz J, Orus J, Roque M, Heras M, Roig E. Correlation between mast cell density and myocardial fibrosis in congestive heart failure patients. Transplant Proc 2007, 39, 2347-2349. https://doi.org/10.1016/j.transproceed.2007.06.047
  2. Craig LE, Hardam EE, Hertzke DM, Flatland B, Rohrbach BW, Moore RR. Feline gastrointestinal eosinophilic sclerosing fibroplasia. Vet Pathol 2009, 46, 63-70. https://doi.org/10.1354/vp.46-1-63
  3. Gomes I, Mathur SK, Espenshade BM, Mori Y, Varga J, Ackerman SJ. Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: implications in fibrogenesis. J Allergy Clin Immunol 2005, 116, 796-804. https://doi.org/10.1016/j.jaci.2005.06.031
  4. Halsey CHC, Powers BE, Kamstock DA. Feline intestinal sclerosing mast cell tumour: 50 cases (1997-2008). Vet Comp Oncol 2010, 8, 72-79. https://doi.org/10.1111/j.1476-5829.2009.00206.x
  5. Henry C, Herrera C. Mast cell tumors in cats: clinical update and possible new treatment avenues. J Feline Med Surg 2013, 15, 41-47. https://doi.org/10.1177/1098612X12470343
  6. Laurenson MP, Skorupski KA, Moore PF, Zwingenberger AL. Ultrasonography of intestinal mast cell tumors in the cat. Vet Radiol Ultrasound 2011, 52, 330-334. https://doi.org/10.1111/j.1740-8261.2010.01792.x
  7. Litster AL, Sorenmo KU. Characterisation of the signalment, clinical and survival characteristics of 41 cats with mast cell neoplasia. J Feline Med Surg 2006, 8, 177-183. https://doi.org/10.1016/j.jfms.2005.12.005
  8. London CA, Thamm DH. Mast cell tumors. In: Withrow SJ, Vail DM, Page RL (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 5th ed. pp. 335-355, Elsevier Saunders, St. Louis, 2013.
  9. Patnaik AK, Ehler WJ, MacEwen EG. Canine cutaneous mast cell tumor: morphologic grading and survival time in 83 dogs. Vet Pathol 1984, 21, 469-474. https://doi.org/10.1177/030098588402100503
  10. Rissetto K, Villamil JA, Selting KA, Tyler J, Henry CJ. Recent trends in feline intestinal neoplasia: an epidemiologic study of 1,129 cases in the veterinary medical database from 1964 to 2004. J Am Anim Hosp Assoc 2011, 47, 28-36. https://doi.org/10.5326/JAAHA-MS-5554
  11. Seibold JR, Giorno RC, Claman HN. Dermal mast cell degranulation in systemic sclerosis. Arthritis Rheum 1990, 33, 1702-1709. https://doi.org/10.1002/art.1780331114
  12. Shakoory B, Fitzgerald SM, Lee SA, Chi DS, Krishnaswamy G. The role of human mast cell-derived cytokines in eosinophil biology. J Interferon Cytokine Res 2004, 24, 271-281. https://doi.org/10.1089/107999004323065057