성인간호학회지 (Korean Journal of Adult Nursing)

  • 제29권2호
  • /
  • Pages.177-189
  • /
  • 2017
  • /
  • 1225-4886(pISSN)
  • /
  • 2288-338X(eISSN)
한국성인간호학회 (Korean Society of Adult Nursing)
권호 표지
DOI QR코드

DOI QR Code

한국 경도인지장애 노인을 위한 인지기능 향상 프로그램의 효과: 메타분석

Effect of Cognitive Improvement Programs for Mild Cognitive Impairment in Korean Elderly: A Meta-Analysis

  • 김경윤 (경북대학교 간호대학) ;
  • 이은주 (경북대학교 간호대학.간호과학연구소)
  • Kim, Kyoungyun (College of Nursing, Kyungpook National University) ;
  • Lee, Eunjoo (College of Nursing, Reserch Institute of Nursing Science, Kyungpook National University)
  • 투고 : 2017.02.21
  • 심사 : 2017.04.25
  • 발행 : 2017.04.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Purpose: A meta-analysis was conducted to identify the effect of cognitive improvement programs for the elderly with mild cognitive impairment (MCI) in Korea. Methods: Five databases, as well as relevant reference lists, of studies published from 2000 to 2016, were searched. Fourteen studies were identified. Quality assessments of included studies were conducted using the Scottish Intercollegiate Guidelines Network checklist. An R program was used to analyze effect sizes and to identify possible sources of heterogeneity among studies. The potential for publication bias was investigated using a funnel plot, Egger's regression test and sensitivity analysis. Results: The total effect size was large (Standardized Mean Difference [SMD]=1.44, 95% CI: 1.11~1.77), with cognition based intervention (SMD= 1.77, 95% CI: 1.26~2.29) and exercise intervention (SMD=1.13, 95% CI: 0.82~1.44). Statistically significant moderators were identified intervention type by meta-ANOVA analyses. Finally, no significant evidence of publication bias was found. Conclusion: There is clear evidence that cognitive improvement programs can greatly enhance cognition in elderly with MCI. Future research should examine the effects of non-pharmacological interventions targeting elderly populations with mild-to-severe cognitive impairment in order to develop and enhance the effectiveness of cognitive improvement programs in Korea.

키워드

참고문헌

  1. Statistics Korea. 2015 elderly statistics [Intenet]. Seoul: Statistics Korea; 2015 [cited 2015 september 24]. Available from: http://kostat.go.kr/portal/korea/kor_nw/2/1/index.board?bm ode=read&aSeq=348565
  2. Ministry of Health & Welfare. National dementia strategy 2013-2015 [Internet]. Seoul: Ministry of Health & Welfare; 2012 [cited 2012 July 27]. Available from: http://www.silverweb.or.kr/_data/board_list_file/1/2012/1207301339541.pdf
  3. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR, Kawas CH, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2011;7(3):263-9. https://doi.org/10.1016/j.jalz.2011.03.005
  4. Hahn SJ, Paik NJ. Pharmacological treatment of dementia. Brain & Neurorehabilitation. 2015;8(1):19-23. https://doi.org/10.12786/bn.2015.8.1.19
  5. Jorm AF, Dear KB, Burgess NM. Projections of future numbers of dementia cases in Australia with and without prevention. The Australian and New Zealand Journal of Psychiatry. 2005;39(11-12):959-63. https://doi.org/10.1111/j.1440-1614.2005.01713.x
  6. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, et al. Current concepts in mild cognitive impairment. Archives of Neurology. 2001;58(12):1985-92. https://doi.org/10.1001/archneur.58.12.1985
  7. Kim WY, Han CH, Heo EJ, Kang HW, Jeon WK. A review of non-pharmacological intervention efficacy in patients with mild cognitive impairment. Journal of Oriental Neuropsychiatry. 2011;22(3):1-11. https://doi.org/10.7231/JON.2011.22.3.001
  8. Rozzini L, Costardi D, Chilovi BV, Franzoni S, Trabucchi M, Padovani A. Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors. International Journal of Geriatric Psychiatry. 2007;22(4):356-60. https://doi.org/10.1002/gps.1681
  9. Li H, Li J, Li N, Li B, Wang P, Zhou T. Cognitive intervention for persons with mild cognitive impairment: a meta-analysis. Ageing Research Reviews. 2011;10(2):285-96. https://doi.org/10.1016/j.arr.2010.11.003
  10. Wang C, Yu JT, Wang HF, Tan CC, Meng XF, Tan L. Non-pharmacological interventions for patients with mild cognitive impairment: a meta-analysis of randomized controlled trials of cognition-based and exercise interventions. Journal of Alzheimer's Disease: JAD. 2014;42(2):663-78. https://doi.org/10.3233/jad-140660
  11. Han JW, Seo JY, So YS, Kim KY, Ryu SH, Jeong HG, et al. Physical activity in individuals with dementia or mild cognitive impairment: a meta-analysis study. Alzheimer's & Dementia. 2014;10(4):457.
  12. Jeong PY, Sung JE, Sim HS. Meta-analysis of cognition-focused intervention for people with mild cognitive impairment and dementia. Communication Sciences & Disorders. 2014;19(2):199-212. https://doi.org/10.12963/csd.14122
  13. Lee DY, Lee SJ, Kim YH, Kim JH, Kim HJ, Lee HJ. 2014 literature review for dementia prevention program development. Seoul: Seoul Dementia Center; 2014. p. 1-51.
  14. Ministry of Health & Welfare. Clinical practice guideline for dementia part I: diagnosis & evaluation. Seoul: Clinical Research Center for Dementia; 2009. p. 1-126.
  15. Organisation for Economic Co-operation and Development (OECD). OECD skills outlook 2013: First results from the survey of adult skills. Paris: OECD Publishing; 2013. https://doi.org/10.1787/9789264204256-en
  16. Higgins JPT, Green S. editors. Cochrane handbook for systematic reviews of interventions version 5.1.0 [Internet]. London, UK: The cochrane collaboration; 2011 [cited 2011 March 20]. Available from: http://handbook.cochrane.org/
  17. Larzelere RE, Kuhn BR, Johnson B. The intervention selection bias: an underrecognized confound in intervention research. Psychological Bulletin. 2004;130(2):289-303. https://doi.org/10.1037/0033-2909.130.2.289
  18. Littell JH, Corcoran J, Pillai V. Systematic reviews and metaanalysis. First ed. Jung IS, Jun SS, Hwang SK, Kim DH, Ha JY, translator. Seoul: Soomoonsa; 2011.
  19. Scottish Intercollegiate Guidelines Network. SIGN 50: a guideline developer's handbook [Internet]. Edinburgh, UK: Author; 2015 [cited 2015 November]. Available from: http://www.sign.ac.uk
  20. R package version 3.3.2 [Internet]. The comprehensive R archive network; 2016 [cited 2016 october 31]. Available from: https://www.r-project.org/
  21. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Introduction to meta-analysis. West Sussex, UK: John Wiley & Sons, Ltd.; 2009.
  22. Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ: British Medical Journal. 1997;315(7109):629-34. https://doi.org/10.1136/bmj.315.7109.629
  23. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale, New Jersy: Lawrece Erlbaum Associates; 1998.
  24. Hwang SD. Meta-analysis using R. Hakjisa Seoul: Kim JH; 2015.
  25. Kim HJ, Im HJ. Assessment of dementia. Brain & Neurorehabilitation. 2015;8(1):11-8. https://doi.org/10.12786/bn.2015.8.1.11
  26. Herbison P, Hay-Smith J, Gillespie WJ. Adjustment of metaanalysis on the basis of quality score should be abandoned. Journal of Clinical Epidemiology. 2006;59(12):1249-56.
  27. Juni P, Altman DG, Egger M. Assessing the quality of controlled clinical trials. British Medical Journal. 2001;323(7303):42-6. https://doi.org/10.1136/bmj.323.7303.42
  28. Scher LS, Maynard RA, Stagner M. Interventions intended to reduce pregnancy related outcomes among teenagers. Campbell Systematic Reviews. 2006;12.

피인용 문헌

  1. Effects of Exercise and Cognitive Intervention Program on Cognitive Function, Sedentary Behavior and Health-Related Quality of Life in Elderly Women with Mild Cognitive Impairment vol.28, pp.2, 2017, https://doi.org/10.15857/ksep.2019.28.2.198