Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Efficient Microwave-assisted Deoxydehydration (DODH) Reactions: Synthesis of Adipic Acid from Galactose

마이크로웨이브를 이용한 효율적인 탈산소탈수(DODH) 반응: 갈락토스 유래 아디픽산의 합성

  • Shin, Nara (Department of Chemical and Biological Engineering, Seoul National University,) ;
  • Kwon, Sohyun (Department of Chemical and Biological Engineering, Seoul National University,) ;
  • Kim, Young Gyu (Department of Chemical and Biological Engineering, Seoul National University,)
  • 신나라 (서울대학교 공과대학 화학생물공학부) ;
  • 권소현 (서울대학교 공과대학 화학생물공학부) ;
  • 김영규 (서울대학교 공과대학 화학생물공학부)
  • Received : 2016.12.13
  • Accepted : 2017.02.05
  • Published : 2017.04.10
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Abstract

An efficient synthetic process for bio-based adipic acid, a monomer for nylon 66, was developed from galactose. Galactaric acid, prepared from a mild oxidation of galactose using a Pt catalyst, was successfully converted to muconate, a key intermediate for adipic acid, by an efficient microwave-assisted DODH (deoxydehydration) reaction. The high efficiency of the microwave-assisted reaction greatly reduced the overall reaction time to 30 min. and resulted in an excellent yield of 97% of muconate. The catalytic hydrogenation of muconate followed by the acidic hydrolysis successfully produced the desired adipic acid in high purity after recrystallization.

나일론의 단량체인 아디픽산을 바이오매스인 갈락토스로부터 얻기 위한 효율적인 합성법을 개발하였다. 백금촉매를 이용한 갈락토스의 산화반응을 통해 얻어진 갈락타릭산으로부터 마이크로웨이브를 이용한 탈산소탈수(DODH)반응을 통하여 30 min의 매우 짧은 반응 시간 안에 97%의 높은 수율로 아디픽산의 주요 중간체인 뮤코네이트를 합성하였다. 생성된 뮤코네이트는 팔라듐 촉매를 이용한 수소화 반응 및 가수분해 반응을 통하여 성공적으로 나일론의 단량체인 고순도의 아디픽산으로 전환되었다.

Keywords

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