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Methanol-Induced Encephalopathy: a Case Report

  • Kim, Hyun Jin (Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Sunwoo, Moon Kyung (Department of Neurology, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Lee, Jang Han (Department of Internal Medicine, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Choi, Yong Sun (Department of Internal Medicine, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Kim, Dae Yoon (Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital)
  • Received : 2017.02.26
  • Accepted : 2017.03.15
  • Published : 2017.03.30

Abstract

A characteristic imaging finding in cases of methanol intoxication is putaminal necrosis, but its presence is usually not suspected due to its rarity. Methanol intoxication generally produces serious neurological symptoms that include visual disturbances and diminished consciousness, characteristically with metabolic acidosis. We reported the case of a 59-year-old man who was admitted to the hospital with diminished consciousness. Acute methanol intoxication was determined as the cause. Laboratory tests revealed high anion gap metabolic acidosis. Diffusion-weighted MRI indicated diffuse symmetric diffusion restriction lesions in the subcortical white matter of both cerebral hemispheres.

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References

  1. Sefidbakht S, Rasekhi AR, Kamali K, et al. Methanol poisoning: acute MR and CT findings in nine patients. Neuroradiology 2007;49:427-435 https://doi.org/10.1007/s00234-007-0210-8
  2. Azeemuddin M, Naqi R. MRI findings in methanol intoxication: a report of three cases. J Pak Med Assoc 2012;62:1099-1101
  3. Blanco M, Casado R, Vazquez F, Pumar JM. CT and MR imaging findings in methanol intoxication. AJNR Am J Neuroradiol 2006;27:452-454
  4. Halavaara J, Valanne L, Setala K. Neuroimaging supports the clinical diagnosis of methanol poisoning. Neuroradiology 2002;44:924-928 https://doi.org/10.1007/s00234-002-0855-2
  5. Sharma P, Eesa M, Scott JN. Toxic and acquired metabolic encephalopathies: MRI appearance. AJR Am J Roentgenol 2009;193:879-886 https://doi.org/10.2214/AJR.08.2257
  6. Kraut JA, Kurtz I. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol 2008;3:208-225 https://doi.org/10.2215/CJN.03220807
  7. Osborn AG. Osborn's brain: imaging, pathology, and anatomy. 1st ed. Salt Lake City, Utah: Amirsys Pub., 2013:809-845
  8. Longo DL, Harrison TR. Harrison's principles of internal medicine. New York, N.Y.: McGraw-Hill Medical, Cop., 2012
  9. Gaul HP, Wallace CJ, Auer RN, Fong TC. MR findings in methanol intoxication. AJNR Am J Neuroradiol 1995;16:1783-1786
  10. Ryu J, Lim KH, Ryu DR, et al. Two cases of methyl alcohol intoxication by sub-chronic inhalation and dermal exposure during aluminum CNC cutting in a small-sized subcontracted factory. Ann Occup Environ Med 2016;28:65 https://doi.org/10.1186/s40557-016-0153-9