Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Primary Intracranial Malignant Melanoma with Extracranial Metastasis

  • Hirota, Kengo (Department of Neurosurgery, Tokyo Women's Medical University Medical Center East) ;
  • Yoshimura, Chika (Department of Neurosurgery, Tokyo Women's Medical University Medical Center East) ;
  • Kubo, Osami (Department of Neurosurgery, Tokyo Women's Medical University Medical Center East) ;
  • Kasuya, Hidetoshi (Department of Neurosurgery, Tokyo Women's Medical University Medical Center East)
  • Received : 2015.06.03
  • Accepted : 2015.09.23
  • Published : 2017.01.01
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Abstract

We report a case of primary intracranial malignant melanoma (PIMM) with extracranial metastases. The patient was an 82-year-old woman diagnosed with PIMM under the left cerebellar tentorium. We performed a tumor resection followed by gamma knife surgery. An magnetic resonance imaging at 11 months after surgery showed a local intracranial recurrence. At 12 months, vertebral metastasis was suspected, and 2-[fluorine-18]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) showed multiple extracranial metastases. She died at 13 months after surgery. Although extracranial metastases of PIMM are extremely rare, we should carefully follow up extracranial metastases together with intracranial ones, especially by FDG-PET/CT, even at an early asymptomatic stage.

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