Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Studies on NO, nNOS, eNOS, iNOS and NE Expression by Acupuncture at SP4, KI4 and LR5

족삼음경의 락혈에 시술된 침 자극에 의한 NO, NOS, NE 발현 연구

  • Lee, Yumi (Deparment of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Shin, Wook (Deparment of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Choi, Donghee (Deparment of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Kim, Mirae (Deparment of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Na, Changsu (Deparment of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Youn, Daehwan (Deparment of Acupoint & Meridian, College of Korean Medicine, Dongshin University)
  • 이유미 (동신대학교 한의과대학 경락경혈학교실) ;
  • 신욱 (동신대학교 한의과대학 경락경혈학교실) ;
  • 최동희 (동신대학교 한의과대학 경락경혈학교실) ;
  • 김미래 (동신대학교 한의과대학 경락경혈학교실) ;
  • 나창수 (동신대학교 한의과대학 경락경혈학교실) ;
  • 윤대환 (동신대학교 한의과대학 경락경혈학교실)
  • Received : 2017.03.13
  • Accepted : 2017.03.21
  • Published : 2017.03.27
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Abstract

Objectives : The acupuncture about acupoint affects the production of NO, NOS, and NE.Local action of acupuncture is important for acupuncture treatment. To prove this, the revelation degree of NO, NOS, and NE was observed by stimulating the acupuncture at the connecting point of SP4, KI4, and LR5 in the depths of Superficial layer, Middle layer and Deep layer. Methods : Needles were inserted into rats, on each right and left sides of the connecting point, SP4, KI4 and LR5 acupoints which are the stream points of the foot meridian. After insertion, needles were retained for three minutes. After the retention, rat was sacrificed via cardiac puncture, and tissues of each SP4, KI4 and LR5 point near meridian vessel was extracted to examine the changes in the expression of NO, NOS and NE. Results : In terms of the effect in NO production, there was significant increase in the Superficial layer, Middle layer and Deep layer at KI4. In terms of the effect in NE production, there was significant decrease in the Superficial layer at SP4 and increase in the Superficial layer, Middle layer and Deep layer at LR5. In terms of the effect in nNOS production, there was significant increase in the Superficial layer, Middle layer and Deep layer at SP4 also in the Superficial layer at KI4. In terms of the effect in eNOS production, there was a significant increase in the Superficial layer, Middle layer and Deep layer at SP4, KI4 and LR5. In terms of the effect in iNOS production, there was significant increase in the Superficial layer, Middle layer and Deep layer at SP4, KI4 and LR5. Conclusions : The effect of acupuncture applied at the connecting point of six meridians of the foot on the activities of NO, NOS and NE could be observed, and it can be induced from the effect of needle stimulation on disrupted local and systemic nervous responses.

Keywords

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