Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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The Effects of Whole Body Vibration in the Aspect of Reducing Abdominal Adipose Tissue in High-Fat Diet Mice Model

고지방 식이 섭취 소동물 모델을 활용한 전신진동 자극의 복부 지방 감소 효능 평가

  • Hwang, Donghyun (Department of Biomedical Engineering, Yonsei University) ;
  • Kim, Seohyun (Department of Biomedical Engineering, Yonsei University) ;
  • Lee, Hana (Department of Biomedical Engineering, Yonsei University) ;
  • lee, Sangyeob (Department of Biomedical Engineering, Yonsei University) ;
  • Seo, Donghyun (Department of Biomedical Engineering, Yonsei University) ;
  • Cho, Seungkwan (Yonsei-Fraunhofer Medical Device Laboratory) ;
  • Chen, Seulgi (Department of Biomedical Engineering, Yonsei University) ;
  • Han, Taeyoung (Fraunhofer Institute IKTS-MD) ;
  • Kim, Han Sung (Department of Biomedical Engineering, Yonsei University)
  • Received : 2016.08.11
  • Accepted : 2017.02.06
  • Published : 2017.02.28
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Abstract

The prevalence of obesity has noticeably increased worldwide over several decades with various complication. Even though anti-obesity drug treatments have been spotlighted by resulting in effective mean weight losses, its adverse effects cannot be overlooked. Thus, this study aimed to evaluate the effects of multi-frequency whole body vibration, one of the mechanical stimulus, as a countermeasure against obesity. Thirty-two-6-week-old C57BL/6J male mice were equally assigned to four groups: the Control group (CON, n = 8), the Sham group (Sham, n = 8), the sham with single frequency whole body vibration (S+V, n = 8), and the sham with multi frequency whole body vibration (S+MV, n = 8). After 4 weeks, morphologic changes in the adipose tissue were evaluated from three-dimensional images using in vivo micro-computed tomography. At 4 weeks, the volume of the abdominal adipose tissue, which had the highest value in Sham group, noticeably reduced in S+MV group compared to it in S+V group. These results implied that the accumulation of abdominal adipose tissue can be effectively reduced through applying multi-frequency whole body vibration.

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References

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