Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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A randomized controlled clinical study of periodontal tissue regeneration using an extracellular matrix-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects

  • Kim, Sulhee (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Chang, Hyeyoon (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Hwang, Jin wook (ESTeam Paris Sud, INSERM UMR-S 935, Paris-Sud University, Paris-Saclay University) ;
  • Kim, Sungtae (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Koo, Ki-Tae (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Kim, Tae-Il (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Seol, Yang-Jo (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Lee, Yong-Moo (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Ku, Young (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Lee, Jong-Ho (Department of Oral and Maxillofacial Surgery, Seoul National University School of Dentistry) ;
  • Rhyu, In-Chul (Department of Periodontology, Seoul National University School of Dentistry)
  • Received : 2017.11.01
  • Accepted : 2017.12.19
  • Published : 2017.12.31
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Abstract

Purpose: The purpose of this study was to investigate the feasibility of regenerative therapy with a collagenated bone graft and resorbable membrane in intrabony defects, and to evaluate the effects of the novel extracellular matrix (ECM)-based membrane clinically and radiologically. Methods: Periodontal tissue regeneration procedure was performed using an ECM-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects around the teeth and implants. A novel extracellular matrix membrane (NEM) and a widely-used membrane (WEM) were randomly applied to the test group and the control group, respectively. Cone-beam computed tomography images were obtained on the day of surgery and 6 months after the procedure. Alginate impressions were taken and plaster models were made 1 week and 6 months postoperatively. Results: The quantity of bone tissue, the dimensional changes of the surgically treated intrabony defects, and the changes in width and height below the grafted bone substitutes showed no significant difference between the test and control groups at the 6-month examination. Conclusions: The use of NEM for periodontal regeneration with a collagenated bovine bone graft showed similar clinical and radiologic results to those obtained using WEM.

Keywords

References

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