미생물학회지 (Korean Journal of Microbiology)

  • 제53권4호
  • /
  • Pages.334-336
  • /
  • 2017
  • /
  • 0440-2413(pISSN)
  • /
  • 2383-9902(eISSN)
한국미생물학회 (The Microbiological Society of Korea)
권호 표지
DOI QR코드

DOI QR Code

사람 치주질환 병소에서 분리된 Porphyromonas gingivalis KCOM 2797의 유전체 염기서열 해독

Draft genome sequence of Porphyromonas gingivalis KCOM 2797 isolated from a human periodontitis lesion

  • 박순낭 (조선대학교 치과대학 구강생화학교실 및 한국구강미생물자원은행) ;
  • 임윤경 (조선대학교 치과대학 구강생화학교실 및 한국구강미생물자원은행) ;
  • 신자영 (마크로젠) ;
  • 노한성 (마크로젠) ;
  • 국중기 (조선대학교 치과대학 구강생화학교실 및 한국구강미생물자원은행)
  • Park, Soon-Nang (Korean Collection for Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University) ;
  • Lim, Yun Kyong (Korean Collection for Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University) ;
  • Shin, Ja Young (Macrogen Inc.) ;
  • Roh, Hanseong (Macrogen Inc.) ;
  • Kook, Joong-Ki (Korean Collection for Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University)
  • 투고 : 2017.08.08
  • 심사 : 2017.10.27
  • 발행 : 2017.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Porphyromonas gingivalis는 그람 음성이면서, 절대 혐기성 및 비운동성 간균이다. P. gingivalis는 치주염 및 치근관 감염의 원인균일 뿐만 아니라, 동맥경화증, 조산 및 알츠하이머 질환과 같은 전신질환과도 연관성이 있다. P. gingivalis KCOM 2797 (= JS2) 균주가 사람 치주염 병소에서 분리되었다. P. gingivalis KCOM 2797 균주의 유전체 염기서열을 해독하여 보고한다.

Porphyromonas gingivalis is a Gram-negative, obligately anaerobic, and nonmotile rod. P. gingivalis is a pathogen of periodontitis and endodontic infection as well as is associated with systemic diseases including atherosclerosis, preterm, and Alzheimer's diseases. P. gingivalis KCOM 2797 (= JS2) was isolated from a human periodontitis lesion. Here, we present the draft genome sequence of P. gingivalis KCOM 2797.

키워드

참고문헌

  1. Bankevich, A., Nurk, S., Antipov, D., Gurevich, A.A., Dvorkin, M., Kulikov, A.S., Lesin, V.M., Nikolenko, S.I., Pham, S., Prjibelski, A.D., et al. 2012. SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing. J. Comput. Biol. 19, 455-477. https://doi.org/10.1089/cmb.2012.0021
  2. Bao, E., Jiang, T., and Girke, T. 2014. AlignGraph: algorithm for secondary de novo genome assembly guided by closely related references. Bioinformatics 30, i319-i328. https://doi.org/10.1093/bioinformatics/btu291
  3. Cho, E., Park, S.N., Lim, Y.K., Shin, Y., Paek, J., Hwang, C.H., Chang, Y.H., and Kook, J.K. 2015. Fusobacterium hwasookii sp. nov., isolated from a human periodontitis lesion. Curr. Microbiol. 70, 169-175. https://doi.org/10.1007/s00284-014-0692-7
  4. Hajishengallis, G., Darveau, R.P., and Curtis, M.A. 2012. The keystone pathogen hypothesis. Nat. Rev. Microbiol. 10, 717-725. https://doi.org/10.1038/nrmicro2873
  5. Hasegawa-Nakamura, K., Tateishi, F., Nakamura, T., Nakajima, Y., Kawamata, K., Douchi, T., Hatae, M., and Noguchi, K. 2011. The possible mechanism of preterm birth associated with periodontopathic Porphyromonas gingivalis. J. Periodontal. Res. 46, 497-504. https://doi.org/10.1111/j.1600-0765.2011.01366.x
  6. Luo, R., Liu, B., Xie, Y., Li, Z., Huang, W., Yuan, J., He, G., Chen, Y., Pan, Q., Liu, Y., et al. 2012. SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience 1, 18. Erratum in: Gigascience 2015. 4, 30. https://doi.org/10.1186/2047-217X-1-18
  7. Olsen, I., Taubman, M.A., and Singhrao, S.K. 2016. Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's disease. J. Oral Microbiol. 8, 33029. https://doi.org/10.3402/jom.v8.33029
  8. Otto, T.D., Sanders, M., Berriman, M., and Newbold, C. 2010. Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology. Bioinformatics 26, 1704-1707. https://doi.org/10.1093/bioinformatics/btq269
  9. Park, S.N., Lim, Y.K., and Kook, J.K. 2013. Development of quantitative real-time PCR primers for detecting 42 oral bacterial species. Arch. Microbiol. 195, 473-482. https://doi.org/10.1007/s00203-013-0896-4
  10. Rajaram, A., Kotrashetti, V.S., Somannavar, P.D., Ingalagi, P., and Bhat, K. 2016. Culture-based identification of pigmented Porphyromonas and Prevotella species in primary endodontic infections. J. Dent. Res. Dent. Clin. Dent. Prospects 10, 136-141. https://doi.org/10.15171/joddd.2016.022
  11. Shah, H.N. and Collins, M.D. 1988. Proposal for reclassification of Bacteroides asaccharolyticus, Bacteroides gingivalis, and Bacteroides endodontalis in a new genus, Porphyromonas. Int. J. Syst. Bacteriol. 38, 128-131. https://doi.org/10.1099/00207713-38-1-128