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Isolation and Identification of Tyrosinase Inhibitors from Loranthus tanakae

  • Hwang, Woonsang (Department of Bio-Health Technology, Kangwon National University) ;
  • Park, Cheolson (Department of Bio-Health Technology, Kangwon National University) ;
  • Kim, Jaehyun (Department of Bio-Health Technology, Kangwon National University) ;
  • Ko, In-Young (Department of Medical Biotechnology, Kangwon National University) ;
  • Lee, Kooyeon (Department of Bio-Health Technology, Kangwon National University)
  • Received : 2017.05.04
  • Accepted : 2017.07.26
  • Published : 2017.12.31

Abstract

Various bioactive substances are found in Loranthus tanakae, including quercetin 3-rhamnoside (1), kaempferol 3-rhamnoside (2), rhamnetin 3-rhamnoside (3), and rhamnocitrin 3-rhamnoside (4), which inhibit tyrosinase. These compounds are mainly found in the EtOAc fraction of L. tanakae extract and demonstrate higher rates of tyrosinase inhibition than ascorbic acid, which was used as a control. Our results suggest that L. tanakae extracts can be utilized in skin whitening cosmetics.

Keywords

References

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