Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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A Case of Malignant Transformation of Layngeal Mucosa after Inhalation Injury 25 Years Ago

흡인성 화상을 입은 환자에서 관찰된 후두점막의 악성변화 1례

  • Lee, Jae Young (Department of Otorhinolaryngology-Head and Neck Surgery, Kyungpook National University School of Medicine, Kyungpook National University Chilgok Hospital) ;
  • Lee, GilJoon (Department of Otorhinolaryngology-Head and Neck Surgery, Kyungpook National University School of Medicine, Kyungpook National University Chilgok Hospital) ;
  • Ahn, Dongbin (Department of Otorhinolaryngology-Head and Neck Surgery, Kyungpook National University School of Medicine, Kyungpook National University Chilgok Hospital) ;
  • Sohn, Jin Ho (Department of Otorhinolaryngology-Head and Neck Surgery, Kyungpook National University School of Medicine, Kyungpook National University Chilgok Hospital)
  • 이재영 (경북대학교 의학전문대학원 칠곡경북대학교병원 이비인후과-두경부외과학교실) ;
  • 이길준 (경북대학교 의학전문대학원 칠곡경북대학교병원 이비인후과-두경부외과학교실) ;
  • 안동빈 (경북대학교 의학전문대학원 칠곡경북대학교병원 이비인후과-두경부외과학교실) ;
  • 손진호 (경북대학교 의학전문대학원 칠곡경북대학교병원 이비인후과-두경부외과학교실)
  • Received : 2017.10.25
  • Accepted : 2017.11.25
  • Published : 2017.12.30
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Abstract

Laryngeal neoplasm is the second most common malignancy of the upper aerodigestive tract. About 85% to 95% of laryngeal malignancies are squamous cell carcinoma that arises from the epithelial lining of the larynx. The exact cause of laryngeal neoplasm is unknown, but certain risk factors can affect the chances of developing it. Chronic inflammation is a mutagen factor confirmed in the carcinogenesis of various tumor. Inhalation injuries cause histopathologic damage to laryngeal mucosa and inflammation change. This long term inflammation may leads to the development of dysplasia and malignant transformation. Recently, we experienced a case of malignant transformation of laryngeal mucosa after inhalation injury patient 25 years ago. Herein, we reported this rare case and review the relevant literature.

Keywords

References

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