Maxillofacial Plastic and Reconstructive Surgery

  • 제38권
  • /
  • Pages.2.1-2.9
  • /
  • 2016
  • /
  • 2288-8101(pISSN)
  • /
  • 2288-8586(eISSN)
대한악안면성형재건외과학회 (Korean Association of Maxillofacial Plastic and Reconstructive Surgeons)
권호 표지
DOI QR코드

DOI QR Code

Computer-aided design/computer-aided manufacturing of hydroxyapatite scaffolds for bone reconstruction in jawbone atrophy: a systematic review and case report

  • Garagiola, Umberto (Biomedical Surgical and Dental Sciences Department, Maxillo-Facial and Odontostomatology Unit, Fondazione Ca Granda IRCCS Ospedale Maggiore Policlinico, University of Milan) ;
  • Grigolato, Roberto (Biomedical Surgical and Dental Sciences Department, Maxillo-Facial and Odontostomatology Unit, Fondazione Ca Granda IRCCS Ospedale Maggiore Policlinico, University of Milan) ;
  • Soldo, Rossano (Biomedical Surgical and Dental Sciences Department, Maxillo-Facial and Odontostomatology Unit, Fondazione Ca Granda IRCCS Ospedale Maggiore Policlinico, University of Milan) ;
  • Bacchini, Marco (Private Practice) ;
  • Bassi, Gianluca (Biomedical Surgical and Dental Sciences Department, Maxillo-Facial and Odontostomatology Unit, Fondazione Ca Granda IRCCS Ospedale Maggiore Policlinico, University of Milan) ;
  • Roncucci, Rachele (Biomedical Surgical and Dental Sciences Department, Maxillo-Facial and Odontostomatology Unit, Fondazione Ca Granda IRCCS Ospedale Maggiore Policlinico, University of Milan) ;
  • De Nardi, Sandro (Private Practice)
  • 투고 : 2015.11.26
  • 심사 : 2015.12.21
  • 발행 : 2016.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Background: We reviewed the biological and mechanical properties of porous hydroxyapatite (HA) compared to other synthetic materials. Computer-aided design/computer-aided manufacturing (CAD/CAM) was also evaluated to estimate its efficacy with clinical and radiological assessments. Method: A systematic search of the electronic literature database of the National Library of Medicine (PubMed-MEDLINE) was performed for articles published in English between January 1985 and September 2013. The inclusion criteria were (1) histological evaluation of the biocompatibility and osteoconductivity of porous HA in vivo and in vitro, (2) evaluation of the mechanical properties of HA in relation to its porosity, (3) comparison of the biological and mechanical properties between several biomaterials, and (4) clinical and radiological evaluation of the precision of CAD/CAM techniques. Results: HA had excellent osteoconductivity and biocompatibility in vitro and in vivo compared to other biomaterials. HA grafts are suitable for milling and finishing, depending on the design. In computed tomography, porous HA is a more resorbable and more osteoconductive material than dense HA; however, its strength decreases exponentially with an increase in porosity. Conclusions: Mechanical tests showed that HA scaffolds with pore diameters ranging from 400 to $1200{\mu}m$ had compressive moduli and strength within the range of the human craniofacial trabecular bone. In conclusion, using CAD/CAM techniques for preparing HA scaffolds may increase graft stability and reduce surgical operating time.

키워드

참고문헌

  1. Lee SW, Kim SG (2014) Membranes for the guided bone regeneration. J Korean Assoc Maxillofac Plast Reconstr Surg 36:239-46 https://doi.org/10.14402/jkamprs.2014.36.6.239
  2. Kim MK, Park YT, Kim SG, Park YW, Lee SK, Choi WS (2012) The effect of a hydroxyapatite and 4-hexylresorcinol combination graft on bone regeneration in the rabbit calvarial defect model. J Korean Assoc Maxillofac Plast Reconstr Surg 34:377-83
  3. Maiorana C, Beretta M, Salina S, Santoro F (2005) Reduction of autogenous bone graft resorption by means of bio-oss coverage: a prospective study. Int J Periodontics Restorative Dent 25:19-25
  4. Szabo G, Huys L, Coulthard P, Maiorana C, Garagiola U, Barabas J et al (2005) A prospective multicenter randomized clinical trial of autogenous bone versus beta-tricalcium phosphate graft alone for bilateral sinus elevation: histologic and histomorphometric evaluation. Int J Oral Maxillofac Implants 20:371-81
  5. Suba Z, Hrabak K, Coulthard P, Maiorana C, Garagiola U, Szabo G et al (2004) Histologic and histomorphometric study of bone regeneration induced by beta-tricalcium phosphate (multicenter study). Orv Hetil 145:1431-7
  6. Velich N, Kadar B, Kiss G, Szigeti K, Garagiola U, Szabo G et al (2006) Effect of human organism on the oxide layer formed on titanium osteosynthesis plates: a surface analytical study. J Craniofac Surg 17:1144-9 https://doi.org/10.1097/01.scs.0000236441.20592.f7
  7. Simunek A, Kopecka D, Somanathan RV, Pilathadka S, Brazda T (2008) Deproteinized bovine bone versus beta-tricalcium phosphate in sinus augmentation surgery: a comparative histologic and histomorphometric study. Int J Oral Maxillofac Implants 23:935-42
  8. Jensen SS, Yeo A, Dard M, Hunziker E, Schenk R, Buser D (2007) Evaluation of a novel biphasic calcium phosphate in standardized bone defects: a histologic and histomorphometric study in mandibles of minipigs. Clin Oral Implants Res 18:752-60 https://doi.org/10.1111/j.1600-0501.2007.01417.x
  9. Buser D, Hoffmann B, Bernard JP, Lussi A, Mettler D, Schenk RK (1998) Evaluation of filling materials in membrane-protected bone defects. A comparative histomorphometric study in the mandibles of miniature pigs. Clin Oral Implants Res 9:137-50 https://doi.org/10.1034/j.1600-0501.1998.090301.x
  10. Garagiola U, Maiorana C, Ghiglione V, Marzo G, Santoro F, Szabo G (2007) Osseointegration and guided bone regeneration in ectodermal dysplasia patients. J Craniofac Surg 18(6):1296-304, Erratum in J Craniofac Surg. 19:871
  11. Jensen SS, Broggini N, Hjorting-Hansen E, Schenk R, Buser D (2006) Bone healing and graft resorption of autograft, anorganic bovine bone and ${\beta}$-tricalcium phosphate. A histologic study in the mandible of minipigs. Clin Oral Implants Res 17:237-43 https://doi.org/10.1111/j.1600-0501.2005.01257.x
  12. Von Arx T, Cochran DL, Hermann JS, Schenk RK, Higginbottom FL, Buser D (2001) Lateral ridge augmentation and implant placement: an experimental study evaluating implant osseointegration in different augmentation materials in the canine mandible. Int J Oral Maxillofac Implants 16:343-54
  13. Le Geros RZ, Lin S, Rohanizadeh R, Mijares D, Le Geros JP (2003) Biphasic calcium phosphate bioceramics: preparation, properties and applications. J Mater Sci Mater Med 14:471-78 https://doi.org/10.1023/A:1023912615421
  14. Boyne PJ (1991) Advances in preprosthetic surgery and implantation. Curr Opinion Dent 1:277-81
  15. Meffert RM, Thomas JR, Hamilton KM, Brownstein CN (1985) Hydroxylapatite as an alloplastic graft for the treatment of human periodontal osseous defects. J Periodontol 56:63-73
  16. Misch CE, Dietsh F (1993) Bone-grafting materials in implant dentistry. Implant Dent 2:158-67 https://doi.org/10.1097/00008505-199309000-00003
  17. Gross JS (1997) Bone grafting materials for dental applications: a practical guide. Compend Contin Educ Dent 18:1013-8, 1020-21,1024
  18. Lane JM (1995) Bone graft substitutes. West J Med 163(6):565-6
  19. Burchardt H (1987) Biology of bone transplantation. Orthop Clin North Am 18:187-96
  20. Del Fabbro M, Testori T, Francetti L, Weinstein R (2004) Systematic review of survival rates for implants placed in the grafted maxillary sinus. Int J Periodontics Restorative Dent 24:565-77
  21. Piattelli A, Piattelli M, Romasco N, Trisi P (1994) Histochemical and laser scanning microscopy characterization of the hydroxyapatite-bone interface: an experimental study in rabbit. Int J Oral Maxillofac Implants 9:163-8
  22. Hollister SJ, Lin CY, Saito E, Schek RD, Taboas JM, Williams JM et al (2005) Engineering craniofacial scaffolds. Orthod Craniofac Res 8:162-73 https://doi.org/10.1111/j.1601-6343.2005.00329.x
  23. Malmstrom J, Adolfsson E, Emanuelsson L, Thomsen P (2008) Bone ingrowth in zirconia and hydroxyapatite scaffolds with identical macroporosity. J Mater Sci Mater Med 19:2983-92 https://doi.org/10.1007/s10856-007-3045-2
  24. Malmstrom J, Slotte C, Adolfsson E, Norderyd O, Thomsen P (2009) Bone response to free form-fabricated hydroxyapatite and zirconia scaffolds: a histological study in the human maxilla. Clin Oral Implants Res 20:379-85 https://doi.org/10.1111/j.1600-0501.2008.01595.x
  25. Park JW, Jang JH, Bae SR, An CH, Suh JY (2009) Bone formation with various bone graft substitutes in critical-sized rat calvarial defect. Clin Oral Implants Res 20:372-8 https://doi.org/10.1111/j.1600-0501.2008.01602.x
  26. Warnke PH, Seitz H, Warnke F, Becker ST, Sivananthan S, Sherry E et al (2010) Ceramic scaffolds produced by computer-assisted 3D printing and sintering: characterization and biocompatibility investigations. J Biomed Mater Res B Appl Biomater 93:212-7
  27. Kwon BJ, Kim J, Kim YH, Lee MH, Baek HS (2013) Biological advantages of porous hydroxyapatite scaffold made by solid freeform fabrication for bone tissue regeneration. Artif Organs 37:663-70 https://doi.org/10.1111/aor.12047
  28. Mangano F, Zecca P, Pozzi-Taubert S, Macchi A, Ricci M, Luongo G et al (2013) Maxillary sinus augmentation using computer-aided design/computer-aided manufacturing (CAD/CAM) technology. Int J Med Robot 9:331-8 https://doi.org/10.1002/rcs.1460
  29. Figliuzzi M, Mangano FG, Fortunato L, De Fazio R, Macchi A, Iezzi G et al (2013) Vertical ridge augmentation of the atrophic posterior mandible with custom-made, computer-aided design/computer-aided manufacturing porous hydroxyapatite scaffolds. J Craniofac Surg 24:856-9 https://doi.org/10.1097/SCS.0b013e31827ca3a7
  30. Mangano F, Macchi A, Shibli JA, Luongo G, Iezzi G (2014) Maxillary ridge augmentation with custom-made CAD/CAM scaffolds. A 1-year prospective study on 10 patients. J Oral Implantol 40:561-9 https://doi.org/10.1563/AAID-JOI-D-12-00122
  31. Farronato G, Garagiola U, Dominici A, Periti G, de Nardi S, Carletti V et al (2010) "Ten-point" 3D cephalometric analysis using low-dosage cone beam computed tomography. Prog Orthod 11:2-12 https://doi.org/10.1016/j.pio.2010.04.007
  32. Mortellaro C, Rimondini L, Farronato G, Garagiola U, Varcellino V, Berrone M (2006) Temporomandibular disorders due to improper surgical treatment of mandibular fracture: clinical report. J Craniofac Surg 17:373-82 https://doi.org/10.1097/00001665-200603000-00032

피인용 문헌

  1. Custom-Made Synthetic Scaffolds for Bone Reconstruction: A Retrospective, Multicenter Clinical Study on 15 Patients vol.2016, pp.None, 2016, https://doi.org/10.1155/2016/5862586
  2. Calcium Phosphate as a Key Material for Socially Responsible Tissue Engineering vol.9, pp.6, 2016, https://doi.org/10.3390/ma9060434
  3. Maxillary resection for cancer, zygomatic implants insertion, and palatal repair as single-stage procedure: report of three cases vol.39, pp.None, 2016, https://doi.org/10.1186/s40902-017-0112-6
  4. Rabbit Calvarial Defect Model for Customized 3D-Printed Bone Grafts vol.24, pp.5, 2016, https://doi.org/10.1089/ten.tec.2017.0474
  5. Mandibular Reconstruction Using a Customized Three-Dimensional Titanium Implant Applied on the Lingual Surface of the Mandible vol.29, pp.2, 2018, https://doi.org/10.1097/scs.0000000000004119
  6. Silk Protein-Based Membrane for Guided Bone Regeneration vol.8, pp.8, 2018, https://doi.org/10.3390/app8081214
  7. Nanofibrous yarn reinforced HA-gelatin composite scaffolds promote bone formation in critical sized alveolar defects in rabbit model vol.13, pp.6, 2018, https://doi.org/10.1088/1748-605x/aadf99
  8. Xeno-Hybrid Composite Scaffold Manufactured with CAD/CAM Technology for Horizontal Bone-Augmentation in Edentulous Atrophic Maxilla: A Short Communication vol.10, pp.8, 2016, https://doi.org/10.3390/app10082659
  9. 3D-Printed Ceramic Bone Scaffolds with Variable Pore Architectures vol.21, pp.18, 2016, https://doi.org/10.3390/ijms21186942
  10. Computer-guided implant surgery for immediate implanting and loading: The STIL technique vol.126, pp.2, 2021, https://doi.org/10.1016/j.prosdent.2020.05.006
  11. Bone Regeneration of a 3D-Printed Alloplastic and Particulate Xenogenic Graft with rhBMP-2 vol.22, pp.22, 2016, https://doi.org/10.3390/ijms222212518