Journal of the Korean Society of Radiology (한국방사선학회논문지)

The Korean Society of Radiology (한국방사선학회)
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Study on the Radiation Dose about Skin Thickness of Rat (For Radiation Damage Tissue Engineering)

쥐의 피부두께에 따른 선량연구

  • Jung, Hongmoon (Department of Radiological Science, Daegu Health College) ;
  • Won, Doyeon (Department of Radiological Science, Daegu Health College) ;
  • Kim, Hyeongyun (Department of Radiological Science, Far East University) ;
  • Jung, Jaeeun (Department of Radiological Science, Daegu Health College) ;
  • Choi, hyeun-woo (Kyungpook National University Hospital Biomedical engineering)
  • 정홍문 (대구보건대학교 방사선과) ;
  • 원도연 (대구보건대학교 방사선과) ;
  • 김형균 (극동대학교 방사선학과) ;
  • 정재은 (대구보건대학교 방사선과) ;
  • 최현우 (경북대학교병원 의공학과)
  • Received : 2016.06.15
  • Accepted : 2016.10.30
  • Published : 2016.10.31
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Abstract

A rat is the most common experimental animal used for the realization of the radiation injury model. The certain thickness of rat skin was prepared by peeling off a rat skin. Radiation level was measured by using this rat skin. Also, The schematic of the formula was made that can predict the radiation absorbed dose (RAD) as a function of the thickness of the rat skin. Consequently, we will provide the RAD information in the realization of in-vitro experimental model regarding the rat's skin thickness by applying the formulas. Moreover, the results from this study can be effectively used for the in-vitro experiment of the rat subcutaneous tissue which was exposed to radiation.

방사선장해 극복을 위한 조직공학실험에서는 다양한 실험방법이 존재한다. 그중에서도 방사선 장해모델을 구현함에 있어서 쥐는 가장 많이 사용되는 실험동물이다. 이번 실험에서는 쥐 피부를 벗긴 후 일정한 두께로 만든 후에 피부 두께에 따른 방사선량을 측정하였다. 또한 쥐의 피부 두께에 따른 방사선 흡수선량을 유추해 날수 있는 수식을 도식화 하였다. 결론적으로 이러한 수식을 적용한다면 방사선장해극복을 위한 조직공학 연구에서 사용하는 다양한 지지체삽입시에 지지체가 받을 수 있는 방사선량의 정도를 유추해 낼 수 있으며 이것을 통하여 쥐 피부두께 피하에 관한 체내 (in-vitro)실험모델 구현 시 방사선량의 정보를 제공하고자 한다. 따라서 이번 연구의 결과를 기반으로 사용한다면 방사선이 노출된 쥐의 피하조직 체내 (in-vitro) 조직공학 실험에서 효과적으로 사용 될 수 있을 것이다.

Keywords

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